A Functional Polymorphism in the Tyrosine Hydroxylase Gene Indicates a Role of Noradrenalinergic Signaling in Sudden Infant Death Syndrome

Journal of Pediatrics

Volumn 153, Issue 2, 2008, Pages 190-193

  Klintschar, Michael ^a,b   Reichenpfader, Barbara ^c   Saternus, Klaus Steffen ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

TYROSINE 3 MONOOXYGENASE;

ARTICLE; BODY POSTURE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GESTATIONAL AGE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL SMOKING; PRIORITY JOURNAL; SLEEP; SUDDEN INFANT DEATH SYNDROME; WINTER;

AUTOPSY; CASE-CONTROL STUDIES; CATECHOLAMINES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; MALE; POLYMORPHISM, GENETIC; SIGNAL TRANSDUCTION; SUDDEN INFANT DEATH; TYROSINE 3-MONOOXYGENASE;

EID: 47049126164     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2008.02.032     Document Type: Article

References (28)

1. Krous H.F., Beckwith J.B., Byard R.W., Rognum T.O., Bajanowski T., Corey T., et al. Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics 114 (2004) 234-238
2. In: Byard R.W., and Krous H.F. (Eds). Sudden infant death syndrome (2001), Arnold, London
3. Saternus K.S. Sudden infant death-focus subject of medico-legal research. Forensic Sci Int 144 (2004) 247-253
4. Opdal S.H., and Rognum T.O. The sudden infant death syndrome gene: does it exist?. Pediatrics 114 (2004) 506-512
5. Schwartz P.J., Priori S.G., Bloise R., Napolitano C., Ronchetti E., Piccinini A., et al. Molecular diagnosis in a child with sudden infant death syndrome. Lancet 358 (2001) 1342-1343
6. Schneider P.M., Wendler C., Riepert T., Braun L., Schacker U., Horn M., et al. Possible association of sudden infant death with partial complement C4 deficiency revealed by post-mortem DNA typing of HLA class II and III genes. Eur J Pediatr 149 (1989) 170-174
7. Opdal S.H., Opstad A., Vege A., and Rognum T.O. IL-10 gene polymorphisms are associated with infectious cause of sudden infant death. Hum Immunol 64 (2003) 1183-1189
8. Weese-Mayer D.E., Berry-Kravis E.M., Maher B.S., Silvestri J.M., Curran M.E., and Marazita M.L. Sudden infant death syndrome: association with a promoter polymorphism of the serotonin transporter gene. Am J Med Genet A 117 (2003) 268-274
9. Pharoah P.O., and Platt M.J. Sudden infant death syndrome in twins and singletons. Twin Res Hum Genet 10 (2007) 644-648
10. Mueller R.A., Lundber D.B., Hedner T., and Jonason J. The neuropharmacology of respiratory control. Pharmacol Rev 34 (1982) 255-262
11. Paterson D.S., Trachtenberg F.L., Thompson E.G., Belliveau R.A., Beggs A.H., Darnall R., et al. Multiple serotonergic brainstem abnormalities in sudden infant death syndrome. JAMA 296 (2006) 2124-2132
12. Hilaire G. Endogenous noradrenaline affects the maturation and function of the respiratory network: possible implication for SIDS. Auton Neurosci 126-127 (2006) 320-323
13. Ozawa Y., Obonai T., Itoh M., Aoki Y., Funayama M., and Takashima S. Catecholaminergic neurons in the diencephalon and basal ganglia of SIDS. Pediatr Neurol 21 (1999) 471-475
14. Parish A.R. Sudden infant death syndrome: a proposed discovery. Med Hypotheses 49 (1997) 177-179
15. Brinkmann B., Klintschar M., Neuhuber F., Huhne J., and Rolf B. Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat. Am J Hum Genet 62 (1998) 1408-1415
16. Albanese V., Biguet N.F., Kiefer H., Bayard E., Mallet J., and Meloni R. Quantitative effects on gene silencing by allelic variation at a tetranucleotide microsatellite. Hum Mol Genet 10 (2001) 1785-1792
17. Zhang L., Rao F., Wessel J., Kennedy B.P., Rana B.K., Taupenot L., et al. Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiol Genomics 19 (2004) 277-291
18. Klintschar M., Immel U.D., Kehlen A., Schwaiger P., Mustafa T., Mannweiler S., Regauer S., Kleiber M., and Hoang-Vu C. Fetal microchimerism in Hashimoto's thyroiditis: a quantitative approach. Eur J Endocrinol 154 (2006) 237-241
19. Klintschar M., and Kubat M. A study of the short tandem repeat systems HUMVWA and HUMTH01 in an Austrian population sample. Int J Legal Med 107 (1995) 329-330
20. Reichenpfader B., Immel U., and Klintschar M. Population data on the AmpFLSTR plus PCR amplification kit in Germans and Austrians. Forensic Sci Int 132 (2003) 84-86
21. De Benedictis G., Carotenuto L., Carrieri G., De Luca M., Falcone E., Rose G., et al. Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2). Eur J Hum Genet 6 (1998) 534-541
22. Herlenius E., and Lagercrantz H. Development of neurotransmitter systems during critical periods. Exp Neurol 190 (2004) S8-S21
23. Goridis C., and Rohrer H. Specification of catecholaminergic and serotonergic neurons. Nat Rev 3 (2002) 531-541
24. Narita N., Narita M., Takashima S., Nakayama M., Nagai T., and Okado N. Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese population. Pediatrics 107 (2001) 690-692
25. Opdal S.H., Vege A., Stave A.K., and Rognum T.O. The complement component C4 in sudden infant death. Eur J Pediatr 158 (1999) 210-212
26. Hirschhorn J.N., Lohmueller K., Byrne E., and Hirschhorn K. A comprehensive review of genetic association studies. Genet Med 2 (2002) 45-61
27. Ioannidis J.P., Ntzani E.E., Trikalinos T.A., and Contopoulos-Ioannidis D.G. Replication validity of genetic association studies. Nat Genet 29 (2001) 306-309
28. Lins A.M., Micka K.A., Sprecher C.J., Taylor J.A., Bacher J.W., Rabbach D.R., et al. Development and population study of an eight-locus short tandem repeat (STR) multiplex system. J Forensic Sci 43 (1998) 1168-1180