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Volumn 10, Issue 5, 2008, Pages 229-235

Objective post-mortem diagnosis of chronic alcohol abuse - A review of studies on new markers

Author keywords

5 Hydroxytryptophol; Autopsy; Carbohydrate deficient transferrin; Chronic alcohol abuse; Ethylglucuronide; Fatty acid ethyl esters

Indexed keywords

5 HYDROXYTRYPTOPHOL; ALCOHOL DERIVATIVE; BIOCHEMICAL MARKER; CARBOHYDRATE DEFICIENT TRANSFERRIN; ETHYLGLUCURONIDE; FATTY ACID ESTER; GLUCURONIDE; PHOSPHATIDYLETHANOL;

EID: 47049122004     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2008.01.006     Document Type: Review
Times cited : (16)

References (39)
  • 2
    • 0042334591 scopus 로고    scopus 로고
    • Alcohol consumption and liver cirrhosis mortality with and without mention of alcohol - the case of Canada
    • Ramstedt M. Alcohol consumption and liver cirrhosis mortality with and without mention of alcohol - the case of Canada. Addiction 98 (2003) 1267-1276
    • (2003) Addiction , vol.98 , pp. 1267-1276
    • Ramstedt, M.1
  • 3
    • 0010563783 scopus 로고    scopus 로고
    • Biochemical tests for acute and chronic alcohol ingestion
    • Karch S.B. (Ed), CRC Press, Boca Raton, Boston, London, New York, Washington DC
    • Helander A., and Jones A.W. Biochemical tests for acute and chronic alcohol ingestion. In: Karch S.B. (Ed). Drug abuse handbook (1998), CRC Press, Boca Raton, Boston, London, New York, Washington DC 374-394
    • (1998) Drug abuse handbook , pp. 374-394
    • Helander, A.1    Jones, A.W.2
  • 4
    • 34548574946 scopus 로고    scopus 로고
    • Surrogate alcohol: what do we know and where do we go?
    • Lachenmeier D.W., Rehm J., and Gmel G. Surrogate alcohol: what do we know and where do we go?. Alcohol Clin Exp Res 31 (2007) 1613-1624
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1613-1624
    • Lachenmeier, D.W.1    Rehm, J.2    Gmel, G.3
  • 5
    • 0000352975 scopus 로고    scopus 로고
    • Objective diagnosis of chronic alcohol abuse - determination of carbohydrate-deficient transferrin (CDT) with capillary electrophoresis
    • Tagliaro F., Bortolotti F., Crivellente F., and Cittadini F. Objective diagnosis of chronic alcohol abuse - determination of carbohydrate-deficient transferrin (CDT) with capillary electrophoresis. Forensic Sci Rev 12 (2000) 133-148
    • (2000) Forensic Sci Rev , vol.12 , pp. 133-148
    • Tagliaro, F.1    Bortolotti, F.2    Crivellente, F.3    Cittadini, F.4
  • 6
    • 0026331891 scopus 로고
    • Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed
    • Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin Chem 37 (1991) 2029-2037
    • (1991) Clin Chem , vol.37 , pp. 2029-2037
    • Stibler, H.1
  • 7
    • 0035152278 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation
    • Arndt T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation. Clin Chem 47 (2001) 13-27
    • (2001) Clin Chem , vol.47 , pp. 13-27
    • Arndt, T.1
  • 8
    • 33747783591 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin (CDT) as a marker of alcohol abuse: a critical review of the literature 2001-2005
    • Bortolotti F., De Paoli G., and Tagliaro F. Carbohydrate-deficient transferrin (CDT) as a marker of alcohol abuse: a critical review of the literature 2001-2005. J Chromatogr B 841 (2006) 96-109
    • (2006) J Chromatogr B , vol.841 , pp. 96-109
    • Bortolotti, F.1    De Paoli, G.2    Tagliaro, F.3
  • 9
    • 0030741525 scopus 로고    scopus 로고
    • Concentrations of transferrin and carbohydrate-deficient transferrin in post-mortem human brain from alcoholics
    • Dodd P.R., and Eckert A.L. Concentrations of transferrin and carbohydrate-deficient transferrin in post-mortem human brain from alcoholics. Addict Biol 2 (1997) 337-348
    • (1997) Addict Biol , vol.2 , pp. 337-348
    • Dodd, P.R.1    Eckert, A.L.2
  • 10
    • 0032911659 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin and alcohol use in medical examiner cases
    • Malcolm R., Anton R.F., Conradi S.E., and Sutherland S. Carbohydrate-deficient transferrin and alcohol use in medical examiner cases. Alcohol 17 (1999) 7-11
    • (1999) Alcohol , vol.17 , pp. 7-11
    • Malcolm, R.1    Anton, R.F.2    Conradi, S.E.3    Sutherland, S.4
  • 11
    • 0033462131 scopus 로고    scopus 로고
    • Review of factors susceptible of influencing post-mortem carbohydrate-deficient transferrin
    • Simonnet C., Dumestre-Toulet V., Kintz P., and Cromb S. Review of factors susceptible of influencing post-mortem carbohydrate-deficient transferrin. Forensic Sci Int 106 (1999) 7-17
    • (1999) Forensic Sci Int , vol.106 , pp. 7-17
    • Simonnet, C.1    Dumestre-Toulet, V.2    Kintz, P.3    Cromb, S.4
  • 12
    • 0342615084 scopus 로고    scopus 로고
    • Vitreous humor carbohydrate-deficient transferring concentrations in the postmortem diagnosis of alcoholism
    • Osuna E., Pérez-Cárceles M.D., Moreno M., Bedate A., Conejero, Abenza J.M., et al. Vitreous humor carbohydrate-deficient transferring concentrations in the postmortem diagnosis of alcoholism. Forensic Sci Int 108 (2000) 205-213
    • (2000) Forensic Sci Int , vol.108 , pp. 205-213
    • Osuna, E.1    Pérez-Cárceles, M.D.2    Moreno, M.3    Bedate, A.4    Conejero5    Abenza, J.M.6
  • 13
    • 0034986597 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin in vitreous humour: a marker of possible withdrawal-related death in alcoholics
    • Berkowicz A., Wallerstedt S., Wall K., and Denison H. Carbohydrate-deficient transferrin in vitreous humour: a marker of possible withdrawal-related death in alcoholics. Alcohol Alcoholism 36 (2001) 231-234
    • (2001) Alcohol Alcoholism , vol.36 , pp. 231-234
    • Berkowicz, A.1    Wallerstedt, S.2    Wall, K.3    Denison, H.4
  • 14
    • 0242594579 scopus 로고    scopus 로고
    • Analysis of carbohydrate-deficient transferrin (CDT) in vitreous humour as a forensic tool for detection of alcohol misuse
    • Berkowicz A., Wallerstedt S., Wall K., and Denison H. Analysis of carbohydrate-deficient transferrin (CDT) in vitreous humour as a forensic tool for detection of alcohol misuse. Forensic Sci Int 137 (2003) 119-124
    • (2003) Forensic Sci Int , vol.137 , pp. 119-124
    • Berkowicz, A.1    Wallerstedt, S.2    Wall, K.3    Denison, H.4
  • 16
    • 0023176794 scopus 로고
    • Metabolism of ethanol by human brain to fatty acid ethyl esters
    • Laposata E.A., Scherrer D.E., Mazow C., and Lange L.G. Metabolism of ethanol by human brain to fatty acid ethyl esters. J Biol Chem 262 (1987) 4653-4657
    • (1987) J Biol Chem , vol.262 , pp. 4653-4657
    • Laposata, E.A.1    Scherrer, D.E.2    Mazow, C.3    Lange, L.G.4
  • 17
    • 0035060506 scopus 로고    scopus 로고
    • Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake
    • Salem R.O., Refaai M.A., Cluette-Brown J.E., Russo J.W., and Laposata M. Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake. Clin Chem 47 (2001) 722-725
    • (2001) Clin Chem , vol.47 , pp. 722-725
    • Salem, R.O.1    Refaai, M.A.2    Cluette-Brown, J.E.3    Russo, J.W.4    Laposata, M.5
  • 18
    • 0036138867 scopus 로고    scopus 로고
    • Liver and adipose tissue fatty acid ethyl esters obtained at autopsy are postmortem markers for premortem ethanol intake
    • Refaai M.A., Nguyen P.N., Steffensen T.S., Evans R.J., Cluette-Brown J.E., and Laposata M. Liver and adipose tissue fatty acid ethyl esters obtained at autopsy are postmortem markers for premortem ethanol intake. Clin Chem 48 (2002) 77-83
    • (2002) Clin Chem , vol.48 , pp. 77-83
    • Refaai, M.A.1    Nguyen, P.N.2    Steffensen, T.S.3    Evans, R.J.4    Cluette-Brown, J.E.5    Laposata, M.6
  • 20
    • 0035202020 scopus 로고    scopus 로고
    • Fatty acid ethyl esters in hair as markers of alcohol consumption. Segmental hair analysis of alcoholics, social drinkers, and teetotallers
    • Auwärter V., Sporkert F., Hartwig S., Pragst F., Vater H., and Diefenbacher A. Fatty acid ethyl esters in hair as markers of alcohol consumption. Segmental hair analysis of alcoholics, social drinkers, and teetotallers. Clin Chem 47 (2001) 2114-2123
    • (2001) Clin Chem , vol.47 , pp. 2114-2123
    • Auwärter, V.1    Sporkert, F.2    Hartwig, S.3    Pragst, F.4    Vater, H.5    Diefenbacher, A.6
  • 21
    • 0037469329 scopus 로고    scopus 로고
    • Effect of hair care and hair cosmetics on the concentrations of fatty acid ethyl esters in hair as markers of chronically elevated alcohol consumption
    • Hartwig S., Auwärter V., and Pragst F. Effect of hair care and hair cosmetics on the concentrations of fatty acid ethyl esters in hair as markers of chronically elevated alcohol consumption. Forensic Sci Int 131 (2003) 90-97
    • (2003) Forensic Sci Int , vol.131 , pp. 90-97
    • Hartwig, S.1    Auwärter, V.2    Pragst, F.3
  • 22
    • 0031024778 scopus 로고    scopus 로고
    • Identification of fatty acid methyl esters (FAMEs) in post-mortem tissue. A new marker of alcohol abuse?
    • Emrich J., Sprung R., Sammler J., and Remberg G. Identification of fatty acid methyl esters (FAMEs) in post-mortem tissue. A new marker of alcohol abuse?. Forensic Sci Int 85 (1997) 41-49
    • (1997) Forensic Sci Int , vol.85 , pp. 41-49
    • Emrich, J.1    Sprung, R.2    Sammler, J.3    Remberg, G.4
  • 23
    • 0033949285 scopus 로고    scopus 로고
    • Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics
    • Varga A., Hansson P., Johnson G., and Alling C. Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics. Clin Chem Acta 299 (2000) 141-150
    • (2000) Clin Chem Acta , vol.299 , pp. 141-150
    • Varga, A.1    Hansson, P.2    Johnson, G.3    Alling, C.4
  • 24
    • 0027966076 scopus 로고
    • Phosphatidylethanol formation and degradation in brains of acutely and repeatedly ethanol-treated rats
    • Lundqvist C., Aradottir S., Alling C., Boyano-Adanez M.C., and Gustavsson L. Phosphatidylethanol formation and degradation in brains of acutely and repeatedly ethanol-treated rats. Neurosci Lett 179 (1994) 127-131
    • (1994) Neurosci Lett , vol.179 , pp. 127-131
    • Lundqvist, C.1    Aradottir, S.2    Alling, C.3    Boyano-Adanez, M.C.4    Gustavsson, L.5
  • 25
    • 0031017802 scopus 로고    scopus 로고
    • Blood phosphatidylethanol as a marker of alcohol abuse: levels in alcoholic males during withdrawal
    • Hansson P., Caron M., Johnson G., Gustavsson L., and Alling C. Blood phosphatidylethanol as a marker of alcohol abuse: levels in alcoholic males during withdrawal. Alcohol Clin Exp Res 21 (1997) 108-110
    • (1997) Alcohol Clin Exp Res , vol.21 , pp. 108-110
    • Hansson, P.1    Caron, M.2    Johnson, G.3    Gustavsson, L.4    Alling, C.5
  • 26
    • 0035199464 scopus 로고    scopus 로고
    • Phosphatidylethanol in post-mortem blood as a marker of previous heavy drinking
    • Hansson P., Varga A., Krantz P., and Alling C. Phosphatidylethanol in post-mortem blood as a marker of previous heavy drinking. Int J Legal Med 115 (2001) 158-161
    • (2001) Int J Legal Med , vol.115 , pp. 158-161
    • Hansson, P.1    Varga, A.2    Krantz, P.3    Alling, C.4
  • 27
    • 0034005909 scopus 로고    scopus 로고
    • Ethyl glucuronide: a marker of recent alcohol consumption with clinical and forensic implications
    • Wurst F.M., Kempter C., Metzger J., Seidl S., and Alt A. Ethyl glucuronide: a marker of recent alcohol consumption with clinical and forensic implications. Alcohol 20 (2000) 111-116
    • (2000) Alcohol , vol.20 , pp. 111-116
    • Wurst, F.M.1    Kempter, C.2    Metzger, J.3    Seidl, S.4    Alt, A.5
  • 28
    • 0037027836 scopus 로고    scopus 로고
    • Chromatographic methods for the determination of markers of chronic and acute alcohol consumption
    • Musshoff F. Chromatographic methods for the determination of markers of chronic and acute alcohol consumption. J Chromatogr B 781 (2002) 457-480
    • (2002) J Chromatogr B , vol.781 , pp. 457-480
    • Musshoff, F.1
  • 29
    • 0033936481 scopus 로고    scopus 로고
    • Determination of ethyl glucuronide in hair samples
    • Alt A., Janda I., Seidl S., and Wurst F.M. Determination of ethyl glucuronide in hair samples. Alcohol Alcoholism 35 (2000) 313-314
    • (2000) Alcohol Alcoholism , vol.35 , pp. 313-314
    • Alt, A.1    Janda, I.2    Seidl, S.3    Wurst, F.M.4
  • 30
    • 4644221788 scopus 로고    scopus 로고
    • Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers
    • Yegles M., Labarthe A., Auwärter V., Hartwig S., Vater H., Wennig R., et al. Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers. Forensic Sci Int 145 (2004) 167-173
    • (2004) Forensic Sci Int , vol.145 , pp. 167-173
    • Yegles, M.1    Labarthe, A.2    Auwärter, V.3    Hartwig, S.4    Vater, H.5    Wennig, R.6
  • 32
    • 30344449758 scopus 로고    scopus 로고
    • Distribution of ethyl glucuronide in rib bone marrow, other tissues and body liquids as proof of alcohol consumption before death
    • Schloegl H., Rost T., Schmidt W., Wurst F.M., and Weinmann W. Distribution of ethyl glucuronide in rib bone marrow, other tissues and body liquids as proof of alcohol consumption before death. Forensic Sci Int 156 (2006) 213-218
    • (2006) Forensic Sci Int , vol.156 , pp. 213-218
    • Schloegl, H.1    Rost, T.2    Schmidt, W.3    Wurst, F.M.4    Weinmann, W.5
  • 34
    • 0027201102 scopus 로고
    • Time course of ethanol-induced changes in serotonin metabolism
    • Helander A., Beck O., acobsson G., Löwenmo C., and Wikström T. Time course of ethanol-induced changes in serotonin metabolism. Life Sci 53 (1993) 847-855
    • (1993) Life Sci , vol.53 , pp. 847-855
    • Helander, A.1    Beck, O.2    acobsson, G.3    Löwenmo, C.4    Wikström, T.5
  • 35
    • 18844384624 scopus 로고    scopus 로고
    • Detection of recent ethanol intake with new markers: comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine
    • Borucki K., Schreiner R., Dierkes J., Jachau K., Krause D., Westphal S., et al. Detection of recent ethanol intake with new markers: comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine. Alcohol Clin Exp Res 29 (2005) 781-787
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 781-787
    • Borucki, K.1    Schreiner, R.2    Dierkes, J.3    Jachau, K.4    Krause, D.5    Westphal, S.6
  • 36
    • 18144391921 scopus 로고    scopus 로고
    • Comparison of serum fatty acid ethyl esters and urinary 5-hydroxytryptophol as biochemical markers of recent ethanol consumption
    • Bisaga A., Laposata M., Xie S., and Evans S.M. Comparison of serum fatty acid ethyl esters and urinary 5-hydroxytryptophol as biochemical markers of recent ethanol consumption. Alcohol Alcoholism 40 (2005) 214-218
    • (2005) Alcohol Alcoholism , vol.40 , pp. 214-218
    • Bisaga, A.1    Laposata, M.2    Xie, S.3    Evans, S.M.4
  • 37
    • 0029064544 scopus 로고
    • Distinguishing ingested ethanol from microbial formation by analysis of urinary 5-hydroxytryptophol and 5-hydroxyindoleacetic acid
    • Helander A., Beck O., and Jones A.W. Distinguishing ingested ethanol from microbial formation by analysis of urinary 5-hydroxytryptophol and 5-hydroxyindoleacetic acid. J Forensic Sci 40 (1995) 95-98
    • (1995) J Forensic Sci , vol.40 , pp. 95-98
    • Helander, A.1    Beck, O.2    Jones, A.W.3
  • 38
    • 2342456429 scopus 로고    scopus 로고
    • Accurate assignment of ethanol origin in postmortem urine: liquid-chromatographic-mass spectrometric determination of serotonin metabolites
    • Johnson R.D., Lewis R.J., Canfield D.V., and Blank C.L. Accurate assignment of ethanol origin in postmortem urine: liquid-chromatographic-mass spectrometric determination of serotonin metabolites. J Chromatogr B 805 (2004) 223-234
    • (2004) J Chromatogr B , vol.805 , pp. 223-234
    • Johnson, R.D.1    Lewis, R.J.2    Canfield, D.V.3    Blank, C.L.4
  • 39
    • 18244409092 scopus 로고    scopus 로고
    • Utilizing the urine 5-HTOL/5-HIAA ratio to determine ethanol origin in civil aviation accident victims
    • Johnson R.D., Lewis R.J., Canfield D.V., Dubowski K.M., and Blank C.L. Utilizing the urine 5-HTOL/5-HIAA ratio to determine ethanol origin in civil aviation accident victims. J Forensic Sci 50 (2005) 670-675
    • (2005) J Forensic Sci , vol.50 , pp. 670-675
    • Johnson, R.D.1    Lewis, R.J.2    Canfield, D.V.3    Dubowski, K.M.4    Blank, C.L.5


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