The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers

Oncogene

Volumn 27, Issue 30, 2008, Pages 4255-4260

  Karam, R ^a,b,c   Carvalho, J ^a   Bruno, I ^b   Graziadio, C ^d   Senz, J ^e   Huntsman, D ^e   Carneiro, F ^a,c   Seruca, R ^a,c   Wilkinson, M F ^b   Oliveira, C ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF TEXAS   (United States)

^c University of Porto   (Portugal)

^d UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

CDH1; E cadherin; Gastric cancer; HDGC; KATO III; NMD

Indexed keywords

INITIATION FACTOR 4A; MESSENGER RNA; PROTEIN SYNTHESIS INHIBITOR; UVOMORULIN;

ALLELE; ARTICLE; CANCER CELL CULTURE; CDH1 GENE; CODON; DOWN REGULATION; FAMILIAL CANCER; GENE; GENE LOCUS; GENE MUTATION; GENETIC TRANSCRIPTION; HEREDITARY DIFFUSE GASTRIC CANCER; HETEROZYGOTE; ONSET AGE; PREMATURE STOP CODON; PRIORITY JOURNAL; STOMACH CANCER; TRANSCRIPTION TERMINATION; UPREGULATION;

ADULT; AGE OF ONSET; AGED; BASE SEQUENCE; CADHERINS; CODON, NONSENSE; DOWN-REGULATION; EUKARYOTIC INITIATION FACTOR-4A; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; MIDDLE AGED; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 47049115051     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.62     Document Type: Article

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