Cholesterol seco-sterol-induced aggregation of methylated amyloid-β peptides - Insights into aldehyde-initiated fibrillization of amyloid-β

Angewandte Chemie - International Edition

Volumn 47, Issue 21, 2008, Pages 3919-3922

  Scheinost, Johanna C ^a   Wang, Hong ^b   Boldt, Grant E ^a   Offer, John ^a   Wentworth Jr , Paul ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Alzheimer's disease; Amyloids; Lipid peroxidation; Methylation; Protein misfolding

Indexed keywords

ALDEHYDES; AMINES; CHEMICAL REACTIONS; CHOLESTEROL; ORGANIC COMPOUNDS;

ALZHEIMER'S DISEASE; AMYLOIDS; LIPID PEROXIDATION; METHYLATION; PROTEIN MISFOLDING;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; ATHERONAL B; ATHERONAL-B; CHOLESTEROL; DRUG DERIVATIVE; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMISTRY; CONFORMATION; KINETICS; METHYLATION; MOLECULAR GENETICS; PARTICLE SIZE; PROTEIN FOLDING; SYNTHESIS; TIME;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; BINDING SITES; CHOLESTEROL; KINETICS; METHYLATION; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PARTICLE SIZE; PEPTIDE FRAGMENTS; PROTEIN FOLDING; TIME FACTORS;

EID: 47049101855     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200705922     Document Type: Article

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