-
2
-
-
0042525899
-
Denaturing high performance liquid chromatography analysis of the DPYD gene in patients with lethal 5-fluorouracil toxicity
-
Ezzeldin H, Johnson MR, Okamoto Y, Diasio R. Denaturing high performance liquid chromatography analysis of the DPYD gene in patients with lethal 5-fluorouracil toxicity. Clin Cancer Res 2003; 9: 3021-3028
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3021-3028
-
-
Ezzeldin, H.1
Johnson, M.R.2
Okamoto, Y.3
Diasio, R.4
-
3
-
-
10844253317
-
Detailed analysis of five mutations in dihydropyrimidine dehydrogenase detected in cancer patients with 5-fluorouracil-related side effects
-
Gross E, Ullrich T, Seck K, Mueller V, de Wit M, von Schilling C, Meindl A, Schmitt M, Kiechle M. Detailed analysis of five mutations in dihydropyrimidine dehydrogenase detected in cancer patients with 5-fluorouracil-related side effects. Hum Mutat 2003; 22: 498
-
(2003)
Hum Mutat
, vol.22
, pp. 498
-
-
Gross, E.1
Ullrich, T.2
Seck, K.3
Mueller, V.4
de Wit, M.5
von Schilling, C.6
Meindl, A.7
Schmitt, M.8
Kiechle, M.9
-
4
-
-
0036303541
-
Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype
-
Johnson MR, Wang K, Diasio RB. Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype. Clin Cancer Res 2002; 8: 768-774
-
(2002)
Clin Cancer Res
, vol.8
, pp. 768-774
-
-
Johnson, M.R.1
Wang, K.2
Diasio, R.B.3
-
5
-
-
0032422075
-
Identification of novel mutations in the dihydropyrimidine dehydrogenase gene in a Japanese patient with 5-fluorouracil toxicity
-
Kouwaki M, Hamajima N, Sumi S, Nonaka M, Sasaki M, Dobashi K, Kidouchi K, Togari H, Wada Y. Identification of novel mutations in the dihydropyrimidine dehydrogenase gene in a Japanese patient with 5-fluorouracil toxicity. Clin Cancer Res 1998; 4: 2999-3004
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2999-3004
-
-
Kouwaki, M.1
Hamajima, N.2
Sumi, S.3
Nonaka, M.4
Sasaki, M.5
Dobashi, K.6
Kidouchi, K.7
Togari, H.8
Wada, Y.9
-
6
-
-
13744251436
-
Systemic therapy for colorectal cancer
-
Meyerhardt JA, Mayer RJ. Systemic therapy for colorectal cancer. N Engl J Med 2005; 352: 476-487
-
(2005)
N Engl J Med
, vol.352
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
7
-
-
33845219798
-
Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance
-
Morel A, Boisdron-Celle M, Fey L, Soulie P, Craipeau MC, Traore S, Gamelin E. Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance. Mol Cancer Ther 2006; 5: 2895-2904
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2895-2904
-
-
Morel, A.1
Boisdron-Celle, M.2
Fey, L.3
Soulie, P.4
Craipeau, M.C.5
Traore, S.6
Gamelin, E.7
-
8
-
-
33845804384
-
Identification of a novel mutation in the dihydropyrimidine dehydrogenase gene in a patient with a lethal outcome following 5-fluorouracil administration and the determination of its frequency in a population of 500 patients with colorectal carcinoma
-
Morel A, Boisdron-Celle M, Fey L, Laine-Cessac P, Gamelin E. Identification of a novel mutation in the dihydropyrimidine dehydrogenase gene in a patient with a lethal outcome following 5-fluorouracil administration and the determination of its frequency in a population of 500 patients with colorectal carcinoma. Clin Biochem 2007; 40: 11-17
-
(2007)
Clin Biochem
, vol.40
, pp. 11-17
-
-
Morel, A.1
Boisdron-Celle, M.2
Fey, L.3
Laine-Cessac, P.4
Gamelin, E.5
-
9
-
-
49249125598
-
-
National Cancer Institute Common Toxicity Criteria
-
National Cancer Institute. National Cancer Institute Common Toxicity Criteria. http://www.fda.gov/cder/cancer/toxicityframe.htm
-
-
-
-
10
-
-
33745927137
-
How may anticancer chemotherapy with fluorouracil be individualised?
-
Ploylearmsaeng SA, Fuhr U, Jetter A. How may anticancer chemotherapy with fluorouracil be individualised? Clin Pharmacokinet 2006; 45: 567-592
-
(2006)
Clin Pharmacokinet
, vol.45
, pp. 567-592
-
-
Ploylearmsaeng, S.A.1
Fuhr, U.2
Jetter, A.3
-
11
-
-
0034808681
-
Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls
-
Raida M, Schwabe W, Häusler P, van Kuilenburg AB, van Gennip AH, Behnke D, Höffken K. Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls. Clin Cancer Res 2001; 7: 2832-2839
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2832-2839
-
-
Raida, M.1
Schwabe, W.2
Häusler, P.3
van Kuilenburg, A.B.4
van Gennip, A.H.5
Behnke, D.6
Höffken, K.7
-
12
-
-
2942648695
-
Four decades of continuing innovation with fluorouracil: Current and future approaches to fluorouracil chemoradiation therapy
-
Rich TA, Shepard RC, Mosley ST. Four decades of continuing innovation with fluorouracil: current and future approaches to fluorouracil chemoradiation therapy. J Clin Oncol 2004; 22: 2214-2232
-
(2004)
J Clin Oncol
, vol.22
, pp. 2214-2232
-
-
Rich, T.A.1
Shepard, R.C.2
Mosley, S.T.3
-
13
-
-
0031016021
-
Mutations at codon 974 of the DPYD gene are a rare event
-
Ridge SA, Brown O, McMurrough J, Fernandez-Salguero P, Evans WE, Gonzalez FJ, McLeod HL. Mutations at codon 974 of the DPYD gene are a rare event. Br J Cancer 1997; 75: 178-179
-
(1997)
Br J Cancer
, vol.75
, pp. 178-179
-
-
Ridge, S.A.1
Brown, O.2
McMurrough, J.3
Fernandez-Salguero, P.4
Evans, W.E.5
Gonzalez, F.J.6
McLeod, H.L.7
-
14
-
-
23844456590
-
Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in a cohort of Caucasian individuals
-
Seck K, Riemer S, Kates R, Ullrich T, Lutz V, Harbeck N, Schmitt M, Kiechle M, Diasio R, Gross E. Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in a cohort of Caucasian individuals. Clin Cancer Res 2005; 11: 5886-5892
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5886-5892
-
-
Seck, K.1
Riemer, S.2
Kates, R.3
Ullrich, T.4
Lutz, V.5
Harbeck, N.6
Schmitt, M.7
Kiechle, M.8
Diasio, R.9
Gross, E.10
-
15
-
-
0034488052
-
Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: Identification of new mutations in the DPD gene
-
van Kuilenburg AB, Haasjes J, Richel DJ, Zoetekouw L, van Lenthe H, De Abreu RA, Maring JG, Vreken P, van Gennip AH. Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene. Clin Cancer Res 2000; 6: 4705-4712
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4705-4712
-
-
van Kuilenburg, A.B.1
Haasjes, J.2
Richel, D.J.3
Zoetekouw, L.4
van Lenthe, H.5
De Abreu, R.A.6
Maring, J.G.7
Vreken, P.8
van Gennip, A.H.9
-
16
-
-
0036798968
-
High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity
-
van Kuilenburg AB, Meinsma R, Zoetekouw L, van Gennip AH. High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity. Pharmacogenetics 2002; 12: 555-558
-
(2002)
Pharmacogenetics
, vol.12
, pp. 555-558
-
-
van Kuilenburg, A.B.1
Meinsma, R.2
Zoetekouw, L.3
van Gennip, A.H.4
-
17
-
-
0345700864
-
Lethal 5-fluorouracil toxicity associated with a novel mutation in the dihydropyrimidine dehydrogenase gene
-
van Kuilenburg AB, Baars JW, Meinsma R, van Gennip AH. Lethal 5-fluorouracil toxicity associated with a novel mutation in the dihydropyrimidine dehydrogenase gene. Ann Oncol 2003; 14: 341-342
-
(2003)
Ann Oncol
, vol.14
, pp. 341-342
-
-
van Kuilenburg, A.B.1
Baars, J.W.2
Meinsma, R.3
van Gennip, A.H.4
-
18
-
-
43749114271
-
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: A prospective clinical trial by the German 5-Fu toxicity study group
-
Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J, Kerb R, Blievernicht J, Fischer J, Hofmann U, Bokemeyer C, Eichelbaum M. Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-Fu toxicity study group. J Clin Oncol 2008; 26: 2131-2138
-
(2008)
J Clin Oncol
, vol.26
, pp. 2131-2138
-
-
Schwab, M.1
Zanger, U.M.2
Marx, C.3
Schaeffeler, E.4
Klein, K.5
Dippon, J.6
Kerb, R.7
Blievernicht, J.8
Fischer, J.9
Hofmann, U.10
Bokemeyer, C.11
Eichelbaum, M.12
|