Diagnostic accuracy of cytology and immunocytology in carcinomatous effusions

Cytopathology

Volumn 19, Issue 4, 2008, Pages 205-211

  Metzgeroth, G ^a   Kuhn, C ^a   Schultheis, B ^a   Hehlmann, R ^a   Hastka, J ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Carcinoma; Cytodiagnosis; Cytological techniques; Cytology; Diagnosis; Effusion; Immunocytology; Laboratory diagnosis; Metastases

Indexed keywords

ANTIBODY; CALRETININ; EPITHELIAL MEMBRANE ANTIGEN; KERATIN;

ARTICLE; CANCER CYTODIAGNOSIS; CARCINOMA; COST EFFECTIVENESS ANALYSIS; CYTOLOGY; DIAGNOSTIC ACCURACY; EFFUSION; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; HUMAN; HUMAN CELL; IMMUNOCYTOLOGY; INTERMETHOD COMPARISON; LYMPHOMA; MAJOR CLINICAL STUDY; MESOTHELIOMA; PRIORITY JOURNAL; TUMOR CELL;

EID: 47049086316     PISSN: 09565507     EISSN: 13652303     Source Type: Journal    
DOI: 10.1111/j.1365-2303.2007.00468.x     Document Type: Article

References (39)

1. Bedrossian CW. Diagnostic problems in serous effusions. Diagn Cytopathol 1998 19 : 131 7.
2. Fetsch PA, Abati A. Immunocytochemistry in effusion cytology: a contemporary review. Cancer 2001 93 : 293 308.
3. Monte SA, Ehya H, Lang WR. Positive effusion cytology as the initial presentation of malignancy. Acta Cytol 1987 31 : 448 52.
4. Osterheld MC, Liette C, Anca M. Image cytometry: an aid for cytological diagnosis of pleural effusions. Diagn Cytopathol 2005 32 : 173 6.
5. Motherby H, Pomjanski N, Kube M et al. Diagnostic DNA-flow- vs -image-cytometry in effusion cytology. Anal Cell Pathol 2002 24 : 5 15.
6. Croonen AM, vand V, Herman CJ, Lindeman J. Cytology, immunopathology and flow cytometry in the diagnosis of pleural and peritoneal effusions. Lab Invest 1988 58 : 725 32.
7. Sahni K, Tribukait B, Einhorn N. Flow cytometric measurement of ploidy and proliferation in effusions of ovarian carcinoma and their possible prognostic significance. Gynecol Oncol 1989 35 : 240 5.
8. Davidson B, Dong HP, Berner A et al. Detection of malignant epithelial cells in effusions using flow cytometric immunophenotyping: an analysis of 92 cases. Am J Clin Pathol 2002 118 : 85 92.
9. L WY. Limitations of detection of malignancy in pleural effusions using ELISA-based TRAP assay: comparison with cytological examination. Cytopathology 2005 16 : 227 32.
10. Abutaily AS, Addis BJ, Roche WR. Immunohistochemistry in the distinction between malignant mesothelioma and pulmonary adenocarcinoma: a critical evaluation of new antibodies. J Clin Pathol 2002 55 : 662 8.
11. Bedrossian CW. Special stains, the old and the new: the impact of immunocytochemistry in effusion cytology. Diagn Cytopathol 1998 18 : 141 9.
12. Marel M, Stastny B, Melinova L. Diagnosis of pleural effusions Experience with clinical studies 1986-1990. Chest 1995 107 : 1598 603.
13. Motherby H, Nadjari B, Friegel P. Diagnostic accuracy of effusion cytology. Diagn Cytopathol 1999 20 : 350 7.
14. Moldenhauer G, Momburg F, Moller P, Schwartz R, Hammerling GJ. Epithelium-specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. Br J Cancer 1987 56 : 714 21.
15. Momburg F, Moldenhauer G, Hammerling GJ, Moller P. Immunohistochemical study of the expression of a Mr 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues. Cancer Res 1987 47 : 2883 91.
16. Edwards PAW. Heterogenous expression of cell-surface antigens in normal epithelia and their tumors, revealed by monoclonal antibodies. Cancer 1985 51 : 149.
17. Brezicka T. Expression of epithelial-cell adhesion molecule (Ep-CAM) in small cell lung cancer as defined by monoclonal antibodies 17-1A and BerEP4. Acta Oncol 2005 44 : 723 7.
18. Latza Z, Niedobitek G, Schwartin R, Nekarda H, Stein H. BerEp4: new monoclonal antibody which distinguishes epithelia from mesothelia. Am J Clin Pathol 1990 43 : 21 9.
19. Morgan RL, De Young BR, McGaughy VR, Niemann TH. MOC-31 aids in the differentiation between adenocarcinoma and reactive mesothelial cells. Cancer 1999 87 : 390 4.
20. Okamoto S, Ito K, Sasano H et al. Ber-EP4 and anti-calretinin antibodies: a useful combination for differential diagnosis of various histological types of ovarian cancer cells and mesothelial cells. Tohoku J Exp Med 2005 206 : 31 40.
21. Pan CC, Chen PC, Ho DM. The diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases. Histopathology 2004 45 : 452 9.
22. Kortsik CS, Werner P, Freudenberg N et al. Immunocytochemical characterization of malignant mesothelioma and carcinoma metastatic to the pleura: IOB3-a new tumor marker. Lung 1995 173 : 79 87 Ref Type: Abstract.
23. Ordonez NG. The diagnostic utility of immunohistochemistry in distinguishing between mesothelioma and renal cell carcinoma: a comparative study. Hum Pathol 2004 35 : 697 710.
24. Ordonez NG. Value of immunohistochemistry in distinguishing peritoneal mesothelioma from serous carcinoma of the ovary and peritoneum: a review and update. Adv Anat Pathol 2006 13 : 16 25.
25. Yaziji H, Battifora H, Barry TS et al. Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. Mod Pathol 2006 19 : 514 23.
26. Ordonez NG. Immunohistochemical diagnosis of epithelioid mesothelioma: an update. Arch Pathol Lab Med 2005 129 : 1407 14.
27. Comin CE, Novelli L, Boddi V, Paglierani M, Dini S. Calretinin, thrombomodulin, CEA, and CD15: a useful combination of immunohistochemical markers for differentiating pleural epithelial mesothelioma from peripheral pulmonary adenocarcinoma. Hum Pathol 2001 32 : 529 36.
28. Carella R, Deleonardi G, D'Errico A et al. Immunohistochemical panels for differentiating epithelial malignant mesothelioma from lung adenocarcinoma: a study with logistic regression analysis. Am J Surg Pathol 2001 25 : 43 50.
29. Ordonez NG. The diagnostic utility of immunohistochemistry and electron microscopy in distinguishing between peritoneal mesotheliomas and serous carcinomas: a comparative study. Mod Pathol 2006 19 : 34 48.
30. Wick MR, Mills SE, Swanson PE. Expression of "myelomonocytic" antigens in mesotheliomas and adenocarcinomas involving the serosal surfaces. Am J Clin Pathol 1990 94 : 18 26.
31. Politi E, Kandaraki C, Apostolopoulou C, Kyritsi T, Koutselini H. Immunocytochemical panel for distinguishing between carcinoma and reactive mesothelial cells in body cavity fluids. Diagn Cytopathol 2005 32 : 151 5.
32. Barberis MC, Faleri M, Veronese S, Casadio C, Viale G. Calretinin A selective marker of normal and neoplastic mesothelial cells in serous effusions. Acta Cytol 1997 41 : 1757 61.
33. Cury PM, Butcher DN, Fisher C, Corrin B, Nicholson AG. Value of the mesothelium-associated antibodies thrombomodulin, cytokeratin 5/6, calretinin, and CD44H in distinguishing epithelioid pleural mesothelioma from adenocarcinoma metastatic to the pleura. Mod Pathol 2000 13 : 107 12.
34. Davidson B, Nielsen S, Christensen J et al. The role of desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells. Am J Surg Pathol 2001 25 : 1405 12.
35. Doglioni C, Tos AP, Laurino L et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol 1996 20 : 1037 46.
36. Leers MP, Aarts MM, Theunissen PH. E-cadherin and calretinin: a useful combination of immunochemical markers for differentiation between mesothelioma and metastatic adenocarcinoma. Histopathology 1998 32 : 209 16.
37. Ordonez NG. Value of calretinin immunostaining in differentiating epithelial mesothelioma from lung adenocarcinoma. Mod Pathol 1998 11 : 929 33.
38. Venrick MG, Sidawy MK. Cytologic evaluation of serous effusions Processing techniques and optimal number of smears for routine preparation. Am J Clin Pathol 1993 99 : 182 6.
39. Jan Hastka. Immunzytologie. Stuttgart : Schattauer 1997.