Corticosteroids in herpes simplex virus encephalitis

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 76, Issue 11, 2005, Pages 1469-

  Openshaw, Harry ^a   Cantin, E M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CHEMOKINE; CORTICOSTEROID; MESSENGER RNA; METHYLPREDNISOLONE; PLACEBO; VALACICLOVIR;

BRAIN EDEMA; CELL INFILTRATION; CLINICAL TRIAL; DRUG EFFICACY; EDITORIAL; ENCEPHALITIS; HERPES SIMPLEX VIRUS; HUMAN; IMMUNOSTIMULATION; INFLAMMATORY CELL; MEDICAL DECISION MAKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; VIRUS LATENCY;

ACYCLOVIR; ANTI-INFLAMMATORY AGENTS; ANTIVIRAL AGENTS; BRAIN; DRUG THERAPY, COMBINATION; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; GLASGOW COMA SCALE; HUMANS; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 27444436549     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2005.071837     Document Type: Editorial

References (4)

1. Cantin EM, Hinton DR, Chen J, et al. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J Virol 1995;69:4898-905.
2. Kurt-Jones EA, Chan M, Shenghua Z, et al. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A 2004;101:1315-20.
3. Meyding-Lamade UK, Oberlinner C, Rau PR, et al. Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities. J Neurovirol 2003;9:118-25.
4. Sellner J, Dvorak F, Zhou Y, et al. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci Lett 2005;374:197-202.