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Volumn 359, Issue 2, 2008, Pages 166-176

Initial management of epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; DEPAKOTE ER; ETIRACETAM; GABAPENTIN; KEPPRA IV; LAMICTAL XR; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTEK; PHENYTOIN; PREGABALIN; TIAGABINE; TOPIRAMATE; VALPROATE SEMISODIUM; VALPROIC ACID; ZONISAMIDE;

EID: 46949111707     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcp0801738     Document Type: Article
Times cited : (97)

References (57)
  • 1
    • 0027152087 scopus 로고
    • Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984
    • Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 1993;34:453-68.
    • (1993) Epilepsia , vol.34 , pp. 453-468
    • Hauser, W.A.1    Annegers, J.F.2    Kurland, L.T.3
  • 3
    • 0032913565 scopus 로고    scopus 로고
    • The incidence of epilepsy and unprovoked seizures in multiethnic, urban health maintenance organizations
    • Annegers JF, Dubinsky S, Coan SP, Newmark ME, Roht L. The incidence of epilepsy and unprovoked seizures in multiethnic, urban health maintenance organizations. Epilepsia 1999;40:502-6.
    • (1999) Epilepsia , vol.40 , pp. 502-506
    • Annegers, J.F.1    Dubinsky, S.2    Coan, S.P.3    Newmark, M.E.4    Roht, L.5
  • 4
    • 43149094816 scopus 로고    scopus 로고
    • Incidence and prevalence
    • Engel J Jr, Pedley TA, eds, 2nd ed. Baltimore: Wolters Kluwer/Lippincott Williams & Wilkins
    • Banerjee PN, Hauser WA. Incidence and prevalence. In: Engel J Jr, Pedley TA, eds. Epilepsy: a comprehensive textbook. 2nd ed. Baltimore: Wolters Kluwer/Lippincott Williams & Wilkins, 2008:45-56.
    • (2008) Epilepsy: A comprehensive textbook , pp. 45-56
    • Banerjee, P.N.1    Hauser, W.A.2
  • 5
    • 31344432875 scopus 로고    scopus 로고
    • Epidemiological and medical aspects of epilepsy in the elderly
    • Cloyd J, Hauser W, Towne A, et al. Epidemiological and medical aspects of epilepsy in the elderly. Epilepsy Res 2006; 68:Suppl 1:S39-S48.
    • (2006) Epilepsy Res , vol.68 , Issue.SUPPL. 1
    • Cloyd, J.1    Hauser, W.2    Towne, A.3
  • 6
    • 0028915209 scopus 로고
    • Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984
    • Annegers JF, Hauser WA, Lee JR, Rocca WA. Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984. Epilepsia 1995;36:327-33.
    • (1995) Epilepsia , vol.36 , pp. 327-333
    • Annegers, J.F.1    Hauser, W.A.2    Lee, J.R.3    Rocca, W.A.4
  • 7
    • 36349008161 scopus 로고    scopus 로고
    • Evaluating an apparent unprovoked first seizure in adults (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • Krumholz A, Wiebe S, Gronseth G, et al. Evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2007;69:1996-2007.
    • (2007) Neurology , vol.69 , pp. 1996-2007
    • Krumholz, A.1    Wiebe, S.2    Gronseth, G.3
  • 8
    • 3142561373 scopus 로고    scopus 로고
    • Activation methods
    • Ebersole JS, Pedley TA, eds, 3rd ed. Philadelphia: Lippincott Williams & Wilkins
    • Fisch B, So E. Activation methods. In: Ebersole JS, Pedley TA, eds. Current practice of clinical electroencephalography. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2003:262-4.
    • (2003) Current practice of clinical electroencephalography , pp. 262-264
    • Fisch, B.1    So, E.2
  • 9
    • 0029836208 scopus 로고    scopus 로고
    • Bronen RA, Fulbright RK, Spencer DD, et al. Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients. Radiology 1996;201:97-105.
    • Bronen RA, Fulbright RK, Spencer DD, et al. Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients. Radiology 1996;201:97-105.
  • 10
    • 35848950205 scopus 로고    scopus 로고
    • Reassessment: Neuroimaging in the emergency patient presenting with seizure (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    • Harden CL, Huff JS, Schwartz TH, et al. Reassessment: neuroimaging in the emergency patient presenting with seizure (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2007;69:1772-80.
    • (2007) Neurology , vol.69 , pp. 1772-1780
    • Harden, C.L.1    Huff, J.S.2    Schwartz, T.H.3
  • 11
    • 85031375223 scopus 로고    scopus 로고
    • Epilepsy Foundation, Accessed June 12, 2008, at
    • Epilepsy Foundation. Driver information by state. (Accessed June 12, 2008, at http://www.epilepsyfoundation.org/living/ wellness/transportation/ drivinglaws.cfm.)
    • Driver information by state
  • 12
    • 0022474698 scopus 로고
    • Depression in epilepsy: Significance and phenomenology
    • Mendez MF, Cummings JL, Benson DF. Depression in epilepsy: significance and phenomenology. Arch Neurol 1986; 43:766-70.
    • (1986) Arch Neurol , vol.43 , pp. 766-770
    • Mendez, M.F.1    Cummings, J.L.2    Benson, D.F.3
  • 15
    • 0033595436 scopus 로고    scopus 로고
    • Kanner AM, Nieto JC. Depressive disorders in epilepsy. Neurology 1999;53:5 Suppl 2:S26-S32.
    • Kanner AM, Nieto JC. Depressive disorders in epilepsy. Neurology 1999;53:5 Suppl 2:S26-S32.
  • 16
    • 46949097162 scopus 로고    scopus 로고
    • Gilliam F, Kanner AM, Sheline Y, eds. Depression and brain dysfunction. New York: Taylor & Francis
    • Gilliam F. Depression and epilepsy. In: Gilliam F, Kanner AM, Sheline Y, eds. Depression and brain dysfunction. New York: Taylor & Francis, 2006:173-88.
    • (2006) Depression and epilepsy , pp. 173-188
    • Gilliam, F.1
  • 18
    • 85031389031 scopus 로고    scopus 로고
    • Epilepsy Foundation. Mood disorders and epilepsy: Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) screeningtool. (Accessed June 12, 2008, at http://www.epilepsyfoundation.org/about/ related/mood/nddietool.cfm.)
    • Epilepsy Foundation. Mood disorders and epilepsy: Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) screeningtool. (Accessed June 12, 2008, at http://www.epilepsyfoundation.org/about/ related/mood/nddietool.cfm.)
  • 19
    • 85031370401 scopus 로고    scopus 로고
    • Food and Drug Administration. Information for healthcare professionals: suicidality and antiepileptic drugs. January 31, 2008. (Accessed May 30, 2008, at http://www.fda.gov/Cder/Drug/InfoSheets/ HCP/antiepilepticsHCP.htm.)
    • Food and Drug Administration. Information for healthcare professionals: suicidality and antiepileptic drugs. January 31, 2008. (Accessed May 30, 2008, at http://www.fda.gov/Cder/Drug/InfoSheets/ HCP/antiepilepticsHCP.htm.)
  • 20
    • 37749033436 scopus 로고    scopus 로고
    • Risk of recurrence after a first unprovoked seizure
    • Berg AT. Risk of recurrence after a first unprovoked seizure. Epilepsia 2008; 49:Suppl 1:13-8.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 1 , pp. 13-18
    • Berg, A.T.1
  • 21
    • 20444401893 scopus 로고    scopus 로고
    • Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: A randomised controlled trial
    • Marson A, Jacoby A, Johnson A, Kim L, Gamble C, Chadwick D. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial. Lancet 2005; 365:2007-13.
    • (2005) Lancet , vol.365 , pp. 2007-2013
    • Marson, A.1    Jacoby, A.2    Johnson, A.3    Kim, L.4    Gamble, C.5    Chadwick, D.6
  • 22
    • 11144356543 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs. I. Treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs. I. Treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004;62:1252-60.
    • (2004) Neurology , vol.62 , pp. 1252-1260
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 23
    • 0031883148 scopus 로고    scopus 로고
    • Antiepileptic drugs as a cause of worsening seizures
    • Perucca E, Gram L, Avanzini G, Dulac O. Antiepileptic drugs as a cause of worsening seizures. Epilepsia 1998;39:5-17.
    • (1998) Epilepsia , vol.39 , pp. 5-17
    • Perucca, E.1    Gram, L.2    Avanzini, G.3    Dulac, O.4
  • 24
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314-9.
    • (2000) N Engl J Med , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 25
    • 33947228816 scopus 로고    scopus 로고
    • The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: An unblinded randomised controlled trial
    • Marson AG, Al-Kharusi AM, Alwaidh M, et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet 2007;369:1016-26.
    • (2007) Lancet , vol.369 , pp. 1016-1026
    • Marson, A.G.1    Al-Kharusi, A.M.2    Alwaidh, M.3
  • 26
    • 1842784823 scopus 로고    scopus 로고
    • Medical genetics: A marker for Stevens-Johnson syndrome
    • Chung WH, Hung SI, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature 2004;428:486.
    • (2004) Nature , vol.428 , pp. 486
    • Chung, W.H.1    Hung, S.I.2    Hong, H.S.3
  • 27
    • 0030694614 scopus 로고    scopus 로고
    • Monotherapy trials of new antiepileptic drugs
    • Beydoun A. Monotherapy trials of new antiepileptic drugs. Epilepsia 1997; 38:Suppl 9:S21-S31.
    • (1997) Epilepsia , vol.38 , Issue.SUPPL. 9
    • Beydoun, A.1
  • 28
    • 13144282677 scopus 로고    scopus 로고
    • Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy
    • Pack AM, Morrell MJ, Marcus R, et al. Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy. Ann Neurol 2005;57:252-7.
    • (2005) Ann Neurol , vol.57 , pp. 252-257
    • Pack, A.M.1    Morrell, M.J.2    Marcus, R.3
  • 29
    • 1642566070 scopus 로고    scopus 로고
    • Treatment of anticonvulsant drug-induced bone disease
    • Drezner MK. Treatment of anticonvulsant drug-induced bone disease. Epilepsy Behav 2004;5:Suppl 2:S41-S47.
    • (2004) Epilepsy Behav , vol.5 , Issue.SUPPL. 2
    • Drezner, M.K.1
  • 30
    • 0023755272 scopus 로고
    • Reproductive endocrine disorders in women with primary generalized epilepsy
    • Bilo L, Meo R, Nappi C, et al. Reproductive endocrine disorders in women with primary generalized epilepsy. Epilepsia 1988;29:612-9.
    • (1988) Epilepsia , vol.29 , pp. 612-619
    • Bilo, L.1    Meo, R.2    Nappi, C.3
  • 31
    • 0035058979 scopus 로고    scopus 로고
    • Valproate and the polycystic ovarian syndrome: Final thoughts
    • Herzog AG, Schachter SC. Valproate and the polycystic ovarian syndrome: final thoughts. Epilepsia 2001;42:311-5.
    • (2001) Epilepsia , vol.42 , pp. 311-315
    • Herzog, A.G.1    Schachter, S.C.2
  • 32
    • 0242353074 scopus 로고    scopus 로고
    • Interictal EEG discharges, reproductive hormones, and menstrual disorders in epilepsy
    • Herzog AG, Coleman AE, Jacobs AR, et al. Interictal EEG discharges, reproductive hormones, and menstrual disorders in epilepsy. Ann Neurol 2003;54:625-37.
    • (2003) Ann Neurol , vol.54 , pp. 625-637
    • Herzog, A.G.1    Coleman, A.E.2    Jacobs, A.R.3
  • 33
    • 0346057978 scopus 로고    scopus 로고
    • [Erratum, Ann Neurol 2004;55:148.]
    • [Erratum, Ann Neurol 2004;55:148.]
  • 34
    • 16444374659 scopus 로고    scopus 로고
    • Sexual hormones and epilepsy: Threat and opportunities
    • Herzog AG, Fowler KM. Sexual hormones and epilepsy: threat and opportunities. Curr Opin Neurol 2005;18:167-72.
    • (2005) Curr Opin Neurol , vol.18 , pp. 167-172
    • Herzog, A.G.1    Fowler, K.M.2
  • 35
    • 0031749077 scopus 로고    scopus 로고
    • Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy
    • Isojärvi JI, Rättyä J, Myllylä VV, et al. Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy. Ann Neurol 1998;43:446-51.
    • (1998) Ann Neurol , vol.43 , pp. 446-451
    • Isojärvi, J.I.1    Rättyä, J.2    Myllylä, V.V.3
  • 37
    • 0042856678 scopus 로고    scopus 로고
    • A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy
    • Betts T, Yarrow H, Dutton N, Greenhill L, Rolfe T. A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy. Seizure 2003;12:323-9.
    • (2003) Seizure , vol.12 , pp. 323-329
    • Betts, T.1    Yarrow, H.2    Dutton, N.3    Greenhill, L.4    Rolfe, T.5
  • 38
    • 34548037777 scopus 로고    scopus 로고
    • Polycystic ovaries and polycystic ovary syndrome in epilepsy: Evidence for neurogonadal disease
    • Harden CL. Polycystic ovaries and polycystic ovary syndrome in epilepsy: evidence for neurogonadal disease. Epilepsy Curr 2005;5:142-6.
    • (2005) Epilepsy Curr , vol.5 , pp. 142-146
    • Harden, C.L.1
  • 40
    • 0037236359 scopus 로고    scopus 로고
    • Epilepsy and pregnancy: Report of an Epilepsy Research Foundation workshop
    • Barrett C, Richens A. Epilepsy and pregnancy: report of an Epilepsy Research Foundation workshop. Epilepsy Res 2003; 52:14 7-87.
    • (2003) Epilepsy Res , vol.52 , Issue.14 , pp. 7-87
    • Barrett, C.1    Richens, A.2
  • 41
    • 33947170324 scopus 로고    scopus 로고
    • Teratogenesis of sodium valproate
    • Duncan S. Teratogenesis of sodium valproate. Curr Opin Neurol 2007;20:175-80.
    • (2007) Curr Opin Neurol , vol.20 , pp. 175-180
    • Duncan, S.1
  • 42
    • 7244257375 scopus 로고    scopus 로고
    • The longer term outcome of children born to mothers with epilepsy
    • Adab N, Kini U, Vinten J, et al. The longer term outcome of children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry 2004;75:1575-83.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 1575-1583
    • Adab, N.1    Kini, U.2    Vinten, J.3
  • 43
    • 15244345581 scopus 로고    scopus 로고
    • Neuropsychological effects of exposure to anticonvulsant medication in utero
    • Vinten J, Adab N, Kini U, Gorry J, Gregg J, Baker GA. Neuropsychological effects of exposure to anticonvulsant medication in utero. Neurology 2005;64:949-54.
    • (2005) Neurology , vol.64 , pp. 949-954
    • Vinten, J.1    Adab, N.2    Kini, U.3    Gorry, J.4    Gregg, J.5    Baker, G.A.6
  • 44
    • 0027869735 scopus 로고
    • Plasma activities of hepatic enzymes in patients on anticonvulsant therapy
    • Mendis GP, Gibberd FB, Hunt HA. Plasma activities of hepatic enzymes in patients on anticonvulsant therapy. Seizure 1993;2:319-23.
    • (1993) Seizure , vol.2 , pp. 319-323
    • Mendis, G.P.1    Gibberd, F.B.2    Hunt, H.A.3
  • 45
    • 8844264414 scopus 로고    scopus 로고
    • Met abolic concerns associated with antiepileptic medications
    • Sheth RD. Met abolic concerns associated with antiepileptic medications. Neurology 2004;63:Suppl 4:S24-S29.
    • (2004) Neurology , vol.63 , Issue.SUPPL. 4
    • Sheth, R.D.1
  • 46
    • 33748712021 scopus 로고    scopus 로고
    • Use of antiepileptic drugs in patients with kidney disease
    • Israni RK, Kasbekar N, Haynes K, Berns JS. Use of antiepileptic drugs in patients with kidney disease. Semin Dial 2006;19:408-16.
    • (2006) Semin Dial , vol.19 , pp. 408-416
    • Israni, R.K.1    Kasbekar, N.2    Haynes, K.3    Berns, J.S.4
  • 47
    • 0038714895 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs
    • Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs. Lancet Neurol 2003;2:473-81.
    • (2003) Lancet Neurol , vol.2 , pp. 473-481
    • Patsalos, P.N.1    Perucca, E.2
  • 48
    • 0018147663 scopus 로고
    • Carbamazepine and bradycardia
    • Herzberg L. Carbamazepine and bradycardia. Lancet 1978;1:1097-8.
    • (1978) Lancet , vol.1 , pp. 1097-1098
    • Herzberg, L.1
  • 49
    • 39749201007 scopus 로고    scopus 로고
    • Valproateinduced thrombocytopenia: A prospective monotherapy study
    • Nasreddine W, Beydoun A. Valproateinduced thrombocytopenia: a prospective monotherapy study. Epilepsia 2008;49: 438-45.
    • (2008) Epilepsia , vol.49 , pp. 438-445
    • Nasreddine, W.1    Beydoun, A.2
  • 50
    • 0028017895 scopus 로고
    • Valproate-mediated disturbances of hemostasis: Relationship to dose and plasma concentration
    • Gidal B, Spencer N, Maly M, et al. Valproate-mediated disturbances of hemostasis: relationship to dose and plasma concentration. Neurology 1994;44:1418-22.
    • (1994) Neurology , vol.44 , pp. 1418-1422
    • Gidal, B.1    Spencer, N.2    Maly, M.3
  • 51
    • 36649019378 scopus 로고    scopus 로고
    • Weight issues for people with epilepsy - a review
    • Ben-Menachem E. Weight issues for people with epilepsy - a review. Epilepsia 2007;48:Suppl 9:42-5.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL. 9 , pp. 42-45
    • Ben-Menachem, E.1
  • 52
    • 33646800201 scopus 로고    scopus 로고
    • Weight change and antiepileptic drugs: Health issues and criteria for appropriate selection of an antiepileptic agent
    • Biton V. Weight change and antiepileptic drugs: health issues and criteria for appropriate selection of an antiepileptic agent. Neurologist 2006;12:163-7.
    • (2006) Neurologist , vol.12 , pp. 163-167
    • Biton, V.1
  • 53
    • 0028221118 scopus 로고
    • Relapse following discontinuation of antiepileptic drugs: A meta-analysis
    • Berg AT, Shinnar S. Relapse following discontinuation of antiepileptic drugs: a meta-analysis. Neurology 1994;44:601-8.
    • (1994) Neurology , vol.44 , pp. 601-608
    • Berg, A.T.1    Shinnar, S.2
  • 54
    • 85031391234 scopus 로고    scopus 로고
    • Antiepileptic drugs-best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies
    • in press
    • Patsalos PN, Berry DJ, Bourgeois BF, et al. Antiepileptic drugs-best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies. Epilepsia (in press).
    • Epilepsia
    • Patsalos, P.N.1    Berry, D.J.2    Bourgeois, B.F.3
  • 55
    • 35148836175 scopus 로고    scopus 로고
    • Generic products of antiepileptic drugs (AEDs): Is it an issue?
    • Bialer M. Generic products of antiepileptic drugs (AEDs): is it an issue? Epilepsia 2007;48:1825-32.
    • (2007) Epilepsia , vol.48 , pp. 1825-1832
    • Bialer, M.1
  • 56
    • 1642367801 scopus 로고    scopus 로고
    • Should antiepileptic drugs be withdrawn in seizure-free patients?
    • Specchio LM, Beghi E. Should antiepileptic drugs be withdrawn in seizure-free patients? CNS Drugs 2004;18:201-12.
    • (2004) CNS Drugs , vol.18 , pp. 201-212
    • Specchio, L.M.1    Beghi, E.2
  • 57
    • 33746124186 scopus 로고    scopus 로고
    • ILAE treatment guidelines: Evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes
    • Glauser T, Ben-Menachem E, Bourgeois B, et al. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 2006;47:1094-120.
    • (2006) Epilepsia , vol.47 , pp. 1094-1120
    • Glauser, T.1    Ben-Menachem, E.2    Bourgeois, B.3


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