VEGF inhibition and renal thrombotic microangiopathy [13]

New England Journal of Medicine

Volumn 359, Issue 2, 2008, Pages 206-

  Nochy, Dominique ^a   Lefaucheur, Carmen ^b   Hill, Gary ^a  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PODOCALYXIN; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; ANGIOGENESIS INHIBITOR; VASCULOTROPIN A; VASCULOTROPIN INHIBITOR;

DRUG WITHDRAWAL; FIBRIN CLOT; GLOMERULOPATHY; GLOMERULUS; HUMAN; KIDNEY CARCINOMA; LETTER; MORPHOLOGY; NONHUMAN; PODOCYTE; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN SYNTHESIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MICROCIRCULATION; MOUSE; NOTE; THROMBOSIS; VASCULARIZATION; DIFFUSION; DISEASE COURSE; ENDOTHELIUM CELL; FLOW RATE; GLOMERULUS BASEMENT MEMBRANE; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; KINETICS; PARTITION COEFFICIENT; PROTEINURIA; VELOCITY;

ANGIOGENESIS INHIBITORS; ANIMALS; HUMANS; KIDNEY GLOMERULUS; MICE; MICROCIRCULATION; PODOCYTES; THROMBOSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 46949103254     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: None     Document Type: Letter

References (4)

1. Eremina V, Sood M, Haigh J, et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003;111:707-16.
2. Eremina V, Cui S, Gerber H, et al. Vascular endothelial growth A signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol 2006;17:724-35.
3. Frangié C, Lefaucheur C, Medioni J, Jacquot C, Hill GS, Nochy D. Renal thrombotic microangiopathy caused by anti-VEGF-antibody treatment for metastatic renal-cell carcinoma. Lancet Oncol 2007;8:177-8.
4. Nochy D, Heudes D, Glotz D, et al. Preeclampsia associated with focal and segmental glomerulosclerosis and glomerular hypertrophy: a morphometric analysis. Clin Nephrol 1994;42: 9-17.