Significance of bronchiectasis in patients with α1- antitrypsin deficiency

American Journal of Respiratory and Critical Care Medicine

Volumn 178, Issue 2, 2008, Pages 208-

  Chan, Edward D ^a   Iseman, Michael D ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ALPHA 1 ANTITRYPSIN DEFICIENCY; BRONCHIECTASIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; EMPHYSEMA; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; LETTER; LUNG LOBE; MYCOBACTERIUM; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR;

EID: 46849116620     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/ajrccm.178.2.208     Document Type: Letter

References (6)

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4. Shapiro L, Pott GB, Ralston AH. Alpha-1-antitrypsin inhibits human immunodeficiency virus type-1. FASEB J 2001;15:115-122.
5. Cantin AM, Woods DE. Aerosolized prolastin suppresses bacterial proliferation in a murine model of chronic Pseudomonas aeruginosa lung infection. Am J Respir Crit Care Med 1999;160:1130-1135.
6. Chan ED, Kaminska AM, Gill W, Chmura K, Feldman NE, Bai X, Floyd CM, Fulton KE, Huitt GA, Strand MJ, et al. Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages. Scand J Infect Dis 2007;39:690-696.