The dysmorphic pulmonary circulation in bronchopulmonary dysplasia: A growing story

American Journal of Respiratory and Critical Care Medicine

Volumn 178, Issue 2, 2008, Pages 114-115

  Abman, Steven H ^a  

^a Children's Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; ENDOGLIN; VASCULOTROPIN;

ARTIFICIAL VENTILATION; EDITORIAL; GESTATIONAL AGE; HISTOLOGY; HUMAN; HYPEROXIA; INFLAMMATION; LUNG DYSPLASIA; LUNG INFECTION; NONHUMAN; PATHOGENESIS; PREMATURITY; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

ANTIGENS, CD; BRONCHOPULMONARY DYSPLASIA; ENDOTHELIUM, VASCULAR; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; LUNG; RECEPTORS, CELL SURFACE; RESPIRATION, ARTIFICIAL; SIGNAL TRANSDUCTION;

EID: 46849111996     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200804-629ED     Document Type: Editorial

References (16)

1. Northway WH, Rosan RC, Porter DY. Pulmonary disease following respiratory therapy of hyaline membrane disease: bronchopumonary dysplasia. N Engl J Med 1967;276:357-368.
2. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001;163:1723-1729.
3. Baraldi E, Filippone M. Chronic lung disease after premature birth. N Engl J Med 2007;357:1946-1955.
4. Coalson JJ. Pathology of chronic lung disease in early infancy. In: Bland RD, Coalson JJ, editors. Chronic lung disease in early infancy. New York: Marcel Dekker; 2000. pp. 85-124.
5. Jakkula M, Le Cras TD, Gebb S, Hirth KP, Tuder RM, Voelkel NF, Abman SH. Inhibition of angiogenesis decrases alveolarization in the developing rat lung. Am J Physiol Lung Cell Mol Physiol 2000;279: L600-L607.
6. Abman SH. BPD: a vascular hypothesis. Am J Respir Crit Care Med 2001;164:1755-1756.
7. Maniscalco WM, Watkins RH, Chess PR, Sinkin RA, Horowitz S, Toia L. Hyperoxic injury decreases alveolar epithelial cell expression of VEGF in neonatal rabbit lung. Am J Respir Cell Mol Biol 1997;16: 557-567.
8. Klekamp JG, Jarzecka K, Perkett EA. Exposure to hyperoxia decreases the expression of VEGF and its receptors in adult rat lungs. Am J Pathol 1999;154:823-831.
9. Gerber HP, Hillan KJ, Ryan AM, Kowalski J, Keller GA, Rangell L, Wright BD, Radtke F, Aguet M, Ferrara N.VEGF isrequiredfor growth and survival in neonatal mice. Development 1999;126:1149-1159.
10. Galambos C, Ng YS, Ali A, Noguchi A, Lovejoy S, D'Amore PA, DeMello DE. Defective pulmonary development in the absence of heparin-binding VEGF isoforms. Am J Respir Cell Mol Biol 2002;27: 194-203.
11. Thebaud B, Ladha R, Michelakis ED, Sawicka M, Thurston G, Eaton F, Hashimoto K, Harry G, Haromy A, Korbutt G, et al. VEGF gene therapy increases survival, promotes lung angiogenesis and prevents alveolar damage in hyperoxia induced lung injury. Circulation 2005; 112:2477-2486.
12. Kunig A, Balasubramaniam V, Markham N, Montgomery G, Grover T, Abman SH. Recombinant human VEGF treatment enhances alve-larization during recovery after hyperoxic lung injury in neonatal rats. Am J Physiol Lung Cell Mol Physiol 2005;289:L529-L535.
13. Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM. Disrupted pulmonary vasculature and decreased VEGF, Flt-1, and TIE-2 in human infants dying with BPD. Am J Respir Crit Care Med 2001;164:1971-1980.
14. De Paepe ME, Patel C, Tsai A, Gundavarapu S, Mao Q. Endoglin (CD105) up-regulation in pulmonary microvasculature of ventilated preterm infants. Am J Respir Crit Care Med 2008;178:180-187.
15. Bernabau C, Conley BA, Very CPH. Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem 2007;102:1375-1388.
16. De Paepe ME, Mao Q, Powell J, Rubin SE, DeKoninck P, Appel N, Dixon M, Gundogan R. Growth of pulmonary microvasculature in ventilated preterm infants. Am J Respir Crit Care Med 2006;173:204-211.