메뉴 건너뛰기




Volumn 215, Issue 3, 2008, Pages 263-272

Loss of heterozygosity at 9q32-33 (DBC1 locus) in primary non-invasive papillary urothelial neoplasm of low malignant potential and low-grade urothelial carcinoma of the bladder and their associated normal urothelium

Author keywords

9q32 33; Bladder cancer; Cell cycle; DBC1 locus; FGFR3; LOH; Recurrence; Urothelium

Indexed keywords

CYCLIN D1; CYCLIN D3; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOKERATIN 20; FIBROBLAST GROWTH FACTOR RECEPTOR 3; KI 67 ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; TUMOR MARKER;

EID: 46849099468     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2353     Document Type: Article
Times cited : (24)

References (38)
  • 1
    • 3142572803 scopus 로고    scopus 로고
    • Non-invasive urothelial neoplasms: According to the most recent WHO classification
    • Lopez-Beltran A, Montironi R. Non-invasive urothelial neoplasms: according to the most recent WHO classification. Eur Urol 2004;46:170-176.
    • (2004) Eur Urol , vol.46 , pp. 170-176
    • Lopez-Beltran, A.1    Montironi, R.2
  • 2
    • 0031846244 scopus 로고    scopus 로고
    • Pussycats and baby tigers: Non-invasive (pTa) and minimally invasive (pT1) bladder carcinomas are not the same
    • Sauter G, Mihatsch MJ. Pussycats and baby tigers: non-invasive (pTa) and minimally invasive (pT1) bladder carcinomas are not the same. J Pathol 1998;185:339-341.
    • (1998) J Pathol , vol.185 , pp. 339-341
    • Sauter, G.1    Mihatsch, M.J.2
  • 3
    • 0036166535 scopus 로고    scopus 로고
    • Preneoplastic non-papillary lesions and conditions of the urinary bladder: An update based on the Ancona International Consultation
    • Lopez-Beltran A, Cheng L, Andersson L, Brausi M, de Matteis A, Montironi R, et al. Preneoplastic non-papillary lesions and conditions of the urinary bladder: an update based on the Ancona International Consultation. Virchows Arch 2002;440:3-11.
    • (2002) Virchows Arch , vol.440 , pp. 3-11
    • Lopez-Beltran, A.1    Cheng, L.2    Andersson, L.3    Brausi, M.4    de Matteis, A.5    Montironi, R.6
  • 4
    • 0030430161 scopus 로고    scopus 로고
    • Cytokeratin 20 as an objective marker of urothelial dysplasia
    • Harnden P, Eardley I, Joyce AD, Southgate J. Cytokeratin 20 as an objective marker of urothelial dysplasia. Br J Urol 1996;78:870- 875.
    • (1996) Br J Urol , vol.78 , pp. 870-875
    • Harnden, P.1    Eardley, I.2    Joyce, A.D.3    Southgate, J.4
  • 7
    • 34047216055 scopus 로고    scopus 로고
    • Chromatin phenotype karyometry can predict recurrence in papillary urothelial neoplasms of low malignant potential
    • Montironi R, Scarpelli M, Lopez-Beltran A, Mazzucchelli R, Alberts D, Ranger-Moore J, et al. Chromatin phenotype karyometry can predict recurrence in papillary urothelial neoplasms of low malignant potential. Cell Oncol 2007;29:47-58.
    • (2007) Cell Oncol , vol.29 , pp. 47-58
    • Montironi, R.1    Scarpelli, M.2    Lopez-Beltran, A.3    Mazzucchelli, R.4    Alberts, D.5    Ranger-Moore, J.6
  • 8
    • 33646351532 scopus 로고    scopus 로고
    • Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance
    • Catto JW, Hartmann A, Stoehr R, Bolderson E, Rehman I, Rosario DJ, et al. Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance. J Urol 2006;175:2323-2330.
    • (2006) J Urol , vol.175 , pp. 2323-2330
    • Catto, J.W.1    Hartmann, A.2    Stoehr, R.3    Bolderson, E.4    Rehman, I.5    Rosario, D.J.6
  • 9
    • 0033030354 scopus 로고    scopus 로고
    • Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma
    • Hartmann A, Moser K, Kriegmair M, Hofstetter A, Hofstaedter F, Knuechel R. Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma. Am J Pathol 1999;154:721-727.
    • (1999) Am J Pathol , vol.154 , pp. 721-727
    • Hartmann, A.1    Moser, K.2    Kriegmair, M.3    Hofstetter, A.4    Hofstaedter, F.5    Knuechel, R.6
  • 12
    • 22144448941 scopus 로고    scopus 로고
    • Chromosomal abnormalities in macroscopically normal urothelium in patients with bladder pT1 and pT2a urothelial carcinoma: A fluorescence in situ hybridization study and correlation with histologic features
    • Mazzucchelli R, Barbisan F, Stramazzotti D, Montironi R, Lopez-Beltran A, Scarpelli M. Chromosomal abnormalities in macroscopically normal urothelium in patients with bladder pT1 and pT2a urothelial carcinoma: a fluorescence in situ hybridization study and correlation with histologic features. Anal Quant Cytol Histol 2005;27:143-151.
    • (2005) Anal Quant Cytol Histol , vol.27 , pp. 143-151
    • Mazzucchelli, R.1    Barbisan, F.2    Stramazzotti, D.3    Montironi, R.4    Lopez-Beltran, A.5    Scarpelli, M.6
  • 13
    • 0033896830 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer
    • Muto S, Horie S, Takahashi S, Tomita K, Kitamura T. Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer. Cancer Res 2000;60:4021-4025.
    • (2000) Cancer Res , vol.60 , pp. 4021-4025
    • Muto, S.1    Horie, S.2    Takahashi, S.3    Tomita, K.4    Kitamura, T.5
  • 14
    • 0037222796 scopus 로고    scopus 로고
    • Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH and FISH analyses
    • Obermann EC, Junker K, Stoehr R, Dietmaier W, Zaak D, Schubert J, et al. Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH and FISH analyses. J Pathol 2003;199:50-57.
    • (2003) J Pathol , vol.199 , pp. 50-57
    • Obermann, E.C.1    Junker, K.2    Stoehr, R.3    Dietmaier, W.4    Zaak, D.5    Schubert, J.6
  • 15
    • 0032950750 scopus 로고    scopus 로고
    • Multifocality of transitional cell carcinoma results from genetic instability of entire transitional epithelium
    • Pycha A, Mian C, Hoftrauer J, Brossner C, Haitel A, Wiener H, et al. Multifocality of transitional cell carcinoma results from genetic instability of entire transitional epithelium. Urology 1999;53:92-97.
    • (1999) Urology , vol.53 , pp. 92-97
    • Pycha, A.1    Mian, C.2    Hoftrauer, J.3    Brossner, C.4    Haitel, A.5    Wiener, H.6
  • 16
    • 0036724214 scopus 로고    scopus 로고
    • Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium
    • Steidl C, Simon R, Burger H, Brinkschmidt C, Hertle L, Bocker W, et al. Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium. J Pathol 2002;198:115-120.
    • (2002) J Pathol , vol.198 , pp. 115-120
    • Steidl, C.1    Simon, R.2    Burger, H.3    Brinkschmidt, C.4    Hertle, L.5    Bocker, W.6
  • 17
    • 20844450906 scopus 로고    scopus 로고
    • Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer
    • Stoehr R, Zietz S, Burger M, Filbeck T, Denzinger S, Obermann EC, et al. Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer. Eur Urol 2005;47:58-63.
    • (2005) Eur Urol , vol.47 , pp. 58-63
    • Stoehr, R.1    Zietz, S.2    Burger, M.3    Filbeck, T.4    Denzinger, S.5    Obermann, E.C.6
  • 18
    • 33745726728 scopus 로고    scopus 로고
    • Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma
    • Dhawan D, Hamdy FC, Rehman I, Patterson J, Cross SS, Feeley KM, et al. Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma. J Pathol 2006;209:336-343.
    • (2006) J Pathol , vol.209 , pp. 336-343
    • Dhawan, D.1    Hamdy, F.C.2    Rehman, I.3    Patterson, J.4    Cross, S.S.5    Feeley, K.M.6
  • 20
    • 0035556288 scopus 로고    scopus 로고
    • Destabilization of chromosome 9 in transitional cell carcinoma of the urinary bladder
    • Kimura F, Florl AR, Seifert HH, Louhelainen J, Maas S, Knowles MA, et al. Destabilization of chromosome 9 in transitional cell carcinoma of the urinary bladder. Br J Cancer 2001;85:1887-1893.
    • (2001) Br J Cancer , vol.85 , pp. 1887-1893
    • Kimura, F.1    Florl, A.R.2    Seifert, H.H.3    Louhelainen, J.4    Maas, S.5    Knowles, M.A.6
  • 21
    • 36048960039 scopus 로고    scopus 로고
    • Tumor suppressor loci in bladder cancer
    • Knowles MA. Tumor suppressor loci in bladder cancer. Front Biosci 2007;12:2233-2251.
    • (2007) Front Biosci , vol.12 , pp. 2233-2251
    • Knowles, M.A.1
  • 22
    • 33646359953 scopus 로고    scopus 로고
    • Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q
    • Lindgren D, Liedberg F, Andersson A, Chebil G, Gudjonsson S, Borg A, et al. Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q. Oncogene 2006;25:2685-2696.
    • (2006) Oncogene , vol.25 , pp. 2685-2696
    • Lindgren, D.1    Liedberg, F.2    Andersson, A.3    Chebil, G.4    Gudjonsson, S.5    Borg, A.6
  • 23
    • 2642670285 scopus 로고    scopus 로고
    • Chromosomal aberrations associated with invasion in papillary superficial bladder cancer
    • Simon R, Burger H, Brinkschmidt C, Bocker W, Hertle L, Terpe HJ. Chromosomal aberrations associated with invasion in papillary superficial bladder cancer. J Pathol 1998;185:345-351.
    • (1998) J Pathol , vol.185 , pp. 345-351
    • Simon, R.1    Burger, H.2    Brinkschmidt, C.3    Bocker, W.4    Hertle, L.5    Terpe, H.J.6
  • 24
    • 0034649509 scopus 로고    scopus 로고
    • Chromosome 9 deletions and recurrence of superficial bladder cancer: Identification of four regions of prognostic interest
    • Simoneau M, LaRue H, Aboulkassim TO, Meyer F, Moore L, Fradet Y. Chromosome 9 deletions and recurrence of superficial bladder cancer: identification of four regions of prognostic interest. Oncogene 2000;19:6317-6323.
    • (2000) Oncogene , vol.19 , pp. 6317-6323
    • Simoneau, M.1    LaRue, H.2    Aboulkassim, T.O.3    Meyer, F.4    Moore, L.5    Fradet, Y.6
  • 25
    • 0042122771 scopus 로고    scopus 로고
    • Clinical significance of allelotype profiling for urothelial carcinoma
    • Tzai TS, Chen HH, Chan SH, Ho CL, Tsai YS, Cheng HL, et al. Clinical significance of allelotype profiling for urothelial carcinoma. Urology 2003;62:378-384.
    • (2003) Urology , vol.62 , pp. 378-384
    • Tzai, T.S.1    Chen, H.H.2    Chan, S.H.3    Ho, C.L.4    Tsai, Y.S.5    Cheng, H.L.6
  • 28
    • 20444461984 scopus 로고    scopus 로고
    • Gene expression profiling of progressive papillary noninvasive carcinomas of the urinary bladder
    • Wild PJ, Herr A, Wissmann C, Stoehr R, Rosenthal A, Zaak D, et al. Gene expression profiling of progressive papillary noninvasive carcinomas of the urinary bladder. Clin Cancer Res 2005;11:4415-4429.
    • (2005) Clin Cancer Res , vol.11 , pp. 4415-4429
    • Wild, P.J.1    Herr, A.2    Wissmann, C.3    Stoehr, R.4    Rosenthal, A.5    Zaak, D.6
  • 30
    • 17744394862 scopus 로고    scopus 로고
    • Hypermethylation at 9q32-33 tumour suppressor region in age-related in normal urothelium and an early and frequent alteration in bladder cancer
    • Habuchi T, Takahashi T, Kakinuma H, Wang L, Tsuchiya N, Satoh S, et al. Hypermethylation at 9q32-33 tumour suppressor region in age-related in normal urothelium and an early and frequent alteration in bladder cancer. Oncogene 2001;20:531-537.
    • (2001) Oncogene , vol.20 , pp. 531-537
    • Habuchi, T.1    Takahashi, T.2    Kakinuma, H.3    Wang, L.4    Tsuchiya, N.5    Satoh, S.6
  • 31
    • 0030965342 scopus 로고    scopus 로고
    • A novel candidate tumour suppressor locus at 9q32-33 in bladder cancer: Localization of the candidate region within a single 840 kb YAC
    • Habuchi T, Yoshida O, Knowles MA. A novel candidate tumour suppressor locus at 9q32-33 in bladder cancer: localization of the candidate region within a single 840 kb YAC. Hum Mol Genet 1997;6:913-919.
    • (1997) Hum Mol Genet , vol.6 , pp. 913-919
    • Habuchi, T.1    Yoshida, O.2    Knowles, M.A.3
  • 32
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • Tomlinson D, Baldo O, Harnden P, Knowles M. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J Pathol 2007;213:91-98.
    • (2007) J Pathol , vol.213 , pp. 91-98
    • Tomlinson, D.1    Baldo, O.2    Harnden, P.3    Knowles, M.4
  • 33
    • 34249775289 scopus 로고    scopus 로고
    • FGFR3 mutations and a normal CK20 staining pattern define low-grade noninvasive urothelial bladder tumours
    • van Oers JM, Wild PJ, Burger M, Denzinger S, Stoehr R, Rosskopf E, et al. FGFR3 mutations and a normal CK20 staining pattern define low-grade noninvasive urothelial bladder tumours. Eur Urol 2007;52:760-768.
    • (2007) Eur Urol , vol.52 , pp. 760-768
    • van Oers, J.M.1    Wild, P.J.2    Burger, M.3    Denzinger, S.4    Stoehr, R.5    Rosskopf, E.6
  • 35
    • 0032833459 scopus 로고    scopus 로고
    • Homozygous deletion at the 9q32-33 candidate tumor suppressor locus in primary human bladder cancer
    • Nishiyama H, Takahashi T, Kakehi Y, Habuchi T, Knowles MA. Homozygous deletion at the 9q32-33 candidate tumor suppressor locus in primary human bladder cancer. Genes Chromosomes Cancer 1999;26:171-175.
    • (1999) Genes Chromosomes Cancer , vol.26 , pp. 171-175
    • Nishiyama, H.1    Takahashi, T.2    Kakehi, Y.3    Habuchi, T.4    Knowles, M.A.5
  • 36
    • 0032978373 scopus 로고    scopus 로고
    • Identification of novel bladder tumour suppressor genes
    • Knowles MA. Identification of novel bladder tumour suppressor genes. Electrophoresis 1999;20:269-279.
    • (1999) Electrophoresis , vol.20 , pp. 269-279
    • Knowles, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.