Impacts of the quinazoline-based alpha1-antagonist, terazosin, and of the sulfonamide derivative, tamsulosin, on serum prostate-specific antigen and prostate volume

Journal of Korean Medical Science

Volumn 23, Issue 3, 2008, Pages 509-513

  Paick, Jae Seung ^a   Min, Chul Cho ^a   Sang, Hoon Song ^a   Soo, Woong Kim ^a   Ja, Hyeon Ku ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Benign prostatic hyperplasia; Prostate volume; Prostate specific antigen; Tamsulosin; Terazosine

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; DRUG DERIVATIVE; PRAZOSIN; PROSTATE SPECIFIC ANTIGEN; SULFONAMIDE; TAMSULOSIN; TERAZOSINE;

AGED; ARTICLE; BLOOD; COMPARATIVE STUDY; HUMAN; MALE; MIDDLE AGED; PATHOLOGY; PROSTATE; PROSTATE HYPERTROPHY; RETROSPECTIVE STUDY; STATISTICAL MODEL; TREATMENT OUTCOME;

ADRENERGIC ALPHA-ANTAGONISTS; AGED; AGED, 80 AND OVER; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; PRAZOSIN; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC HYPERPLASIA; RETROSPECTIVE STUDIES; SULFONAMIDES; TREATMENT OUTCOME;

EID: 46849084336     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2008.23.3.509     Document Type: Article

References (19)

1. Caine M, Pfau A, Perlberg S. The use of alpha-adrenergic blockers in benign prostatic obstruction. Br J Urol 1976; 48: 255-63.
2. Kyprianou N, Litvak JP, Borkowski A, Alexander R, Jacobs SC. Induction of prostate apoptosis by doxazosin in benign prostatic hyperplasia. J Urol 1998; 159: 1810-5.
3. Chon JK, Borkowski A, Partin AW, Isaacs JT, Jacobs SC, Kyprianou N. Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia. J Urol 1999; 161: 2002-8.
4. Yang G, Timme TL, Park SH, Wu X, Wyllie MG, Thompson TC. Transforming growth factor beta 1 transduced mouse prostate reconstitutions: II. Induction of apoptosis by doxazosin. Prostate 1997; 33: 157-63.
5. Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance. J Urol 2003; 169: 1520-5.
6. Rittmaster RS, Norman RW, Thomas LN, Rowden G. Evidence for atrophy and apoptosis in the prostates of men given finasteride. J Clin Endocrinol Metab 1996; 81: 814-9.
7. Brawer MK, Lin DW, Williford WO, Jones K, Lepor H. Effect of finasteride and/or terazosin on serum PSA: results of VA Cooperative Study #359. Prostate 1999; 39: 234-9.
8. Roehrborn CG, Oesterling JE, Olson PJ, Padley RJ. Serial prostate-specific antigen measurements in men with clinically benign prostatic hyperplasia during a 12-month placebo-controlled study with terazosin. HYCAT Investigator Group. Hytrin Community Assessment Trial. Urology 1997; 50: 556-61.
9. Shortliffe LM, Sellers RG, Schachter J. The characterization of nonbacterial prostatitis: search for an etiology. J Urol 1992; 148: 1461-6.
10. Lynne CM, Aballa TC, Wang TJ, Rittenhouse HG, Ferrell SM, Brackett NL. Serum and semen prostate specific antigen concentrations are different in young spinal cord injured men compared to normal controls. J Urol 1999; 162: 89-91.
11. Alexandrino AP, Rogrigues MA, Matsuo T. Evaluation of serum and seminal levels of prostate specific antigen in men with spinal cord injury. J Urol 2004; 171: 2230-2.
12. Terris MK, Stamey TA. Determination of prostate volume by transrectal ultrasound. J Urol 1991; 145: 984-7.
13. Abrams P. Bladder outlet obstruction index, bladder contractility index and bladder voiding efficiency: three simple indices to define bladder voiding function. BJU Int 1999; 84: 14-5.
14. Lepor H, Shapiro E. Prostatic alpha adrenoceptors. Prog Clin Biol Res 1994; 386: 271-7.
15. Kyprianou N, Benning CM. Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis. Cancer Res 2000; 60: 4550-5.
16. Shapiro E, Hartanto V, Lepor H. Quantifying the smooth muscle content of the prostate using double-immunoenzymatic staining and color assisted image analysis. J Urol 1992; 147: 1167-70.
17. Sutkowski DM, Fong CJ, Sensibar JA, Rademaker AW, Sherwood ER, Kozlowski JM, Lee C. Interaction of epidermal growth factor and transforming growth factor beta in human prostatic epithelial cells in culture. Prostate 1992; 21: 133-43.
18. Shapiro E, Hartanto V, Lepor H. The response to alpha blockade in benign prostatic hyperplasia is related to the percent area density of prostate smooth muscle. Prostate 1992; 21: 297-307.
19. Roehrborn CG. Three months' treatment with the alpha1-blocker alfuzosin does not affect total or transition zone volume of the prostate. Prostate Cancer Prostatic Dis 2006; 9: 121-5.