Inactivation of ID-1 gene induces sensitivity of prostate cancer cells to chemotherapeutic drugs

Advances in Experimental Medicine and Biology

Volumn 617, Issue , 2008, Pages 565-572

  Wong, Yong Chuan ^a   Zhang, Xiao Meng ^a   Ling, Ming Tak ^a   Wang, Xiang Hong ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; INHIBITOR OF DIFFERENTIATION 1; PACLITAXEL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; ANTINEOPLASTIC AGENT;

APOPTOSIS; CANCER CELL CULTURE; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE INACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; ARTICLE; CELL CULTURE; CLONOGENIC ASSAY; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; ENZYME ACTIVATION; GENETICS; MALE; METABOLISM; NEOPLASM; PATHOLOGY; PROSTATE TUMOR;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; COLONY-FORMING UNITS ASSAY; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; NEOPLASMS, HORMONE-DEPENDENT; PACLITAXEL; PROSTATIC NEOPLASMS; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 46749150093     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-69080-3_58     Document Type: Conference Paper

References (8)

1. Penson DF, Albertsen PC (2000) Lessons learnt about early prostate cancer from large scale databases: population-based pearls of wisdom. Surg Oncol 11:3-11.
2. Hsing AW, Tsao L, Devesa SS (2000). International trends and patterns of prostate cancer incidence and mortality. Int J Cancer 85:60-67.
3. Ling MT, Wang X, Lee DT, et al. (2004). Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R). Carcinogenesis 25:517-525.
4. Ouyang XS, Wang X, Ling MT, et al. (2002). Id-1 stimulates serum independent prostate cancer cell proliferation through inactivation of p16(INK4a)/pRB pathway. Carcinogenesis 23:721-725.
5. Ling MT, Wang X, Ouyang XS, et al. (2002). Activation of MAPK signaling pathway is essential for Id-1 induced serum independent prostate cancer cell growth. Oncogene 21:8498-505.
6. Ling MT, Wang X, Ouyang XS, et al. (2003). Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells. Oncogene 22:4498-508.
7. Ling MT, Lau TC, Zhou C, et al. (2005). Overexpression of Id-1 in prostate cancer cells promotes angiogenesis, through the activation of vascular endothelial growth factor (VEGF). Carcinogenesis 26(10):1668-1676.
8. Zhang XM, Wang XH, Ling MT, et al. (2006) Inactivation of Id-1 in prostate cancer cells: A potential therapeutic target in inducing chemosensitization to taxol through activation of JNK pathway. Int J Cancer 118:2072-2081.