Id-1 stimulates serum independent prostate cancer cell proliferation through inactivation of p16INK4a/pRB pathway

Carcinogenesis

Volumn 23, Issue 5, 2002, Pages 721-725

  Ouyang, Xue Song ^a   Wang, Xianghong ^a   Ling, Ming Tat ^a   Wong, Hing Lok ^a   Tsao, Sai Wah ^a   Wong, Y C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; PROTEIN P16; PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CARCINOGENESIS; CELL CLONE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL ISOLATION; CELL PROLIFERATION; CLINICAL PATHWAY; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; EXPRESSION VECTOR; GENE INACTIVATION; GENE OVEREXPRESSION; GENETIC STABILITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 0036258713     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.5.721     Document Type: Article

References (24)

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3. Coupling of cell growth control and apoptosis functions of Id proteins
4. Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1
5. Id-1 delays senescence but does not immortalize keratinocytes
6. A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells
7. The helix-loop-helix protein Id2 is overexpressed in human pancreatic cancer
8. Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis
9. Upregulation of TRPM-2, MMP-7 and ID-1 during sex hormone-induced prostate carcinogenesis in the Noble rat
10. Id proteins are dynamically expressed in normal epidermis and dysregulated in squamous cell carcinoma
11. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
12. Overexpression of Id-1 in prostate cancer
13. Id2 specifically alters regulation of the cell cycle by tumour suppressor proteins
14. Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
15. Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a
16. Id proteins control growth induction in mammalian cells
17. Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts
18. Regulation of G1 progression by E2A and Id helix-loop-helix proteins
19. The helix-loop-helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic chondrocytes
20. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
21. The cell cycle and development: Redundant roles of cell cycle regulators
22. Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins
23. Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
24. Loss of the retinoblastoma susceptibility gene (RB1) is a frequent and early event in prostatic tumourigenesis