Simulation of turbulent airflow using a CT based upper airway model of a racehorse

Journal of Biomechanical Engineering

Volumn 130, Issue 3, 2008, Pages

  Rakesh, Vineet ^a   Datta, Ashim K ^a   Ducharme, Normand G ^b   Pease, Anthony P ^c  

^a Department of Biological and Environmental Engineering   (United States)

^b C2 528 Vet College ^*  (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Anatomical diseases; Computational fluid dynamics; Computed tomography; Equine upper airway; Standard k model; Transient airflow

Indexed keywords

BIOMECHANICS; BOUNDARY CONDITIONS; BOUNDARY VALUE PROBLEMS; COMPUTATIONAL FLUID DYNAMICS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC RADIOGRAPHY; ELECTRON ENERGY LOSS SPECTROSCOPY; FLOW RATE; FLUID DYNAMICS; FLUID MECHANICS; GEOMETRY; HEALTH; KINETIC ENERGY; MEDICAL IMAGING; MIXED CONVECTION; NAVIER STOKES EQUATIONS; PHYSIOLOGY; PRESSURE; RESPIRATORY MECHANICS; REYNOLDS NUMBER; STANDARDS; TOMOGRAPHY; TURBULENCE; TURBULENT FLOW;

ABRUPT CHANGE; APPLIED PRESSURE; BREATHING CYCLE; COMPUTATIONAL MODELLING; COMPUTED TOMOGRAPHY (CT) SCANS; CRITICAL INFORMATION; DIFFERENT SECTIONS; EXPERIMENTAL STUDIES; FINITE VOLUMES; FLOW EQUATIONS; FLOW MODELLING; HIGH PRESSURE (HP); HIGH REYNOLDS NUMBERS; HUMAN BEINGS.; INTRALUMINAL PRESSURE; ISOTHERMAL FLOWS; MODEL BASED (OPC); MODEL VALIDATIONS; MUSCULAR ACTIVITY; RESPIRATORY CYCLES; REYNOLDS AVERAGED NAVIER STOKES EQUATIONS (RANSE); SOFT PALATES; TRANSIENT PRESSURES; TREATMENT PLANNING; TURBULENT AIR FLOWS; TURBULENT KINETIC ENERGY (TKE); TWO PHASES; UPPER AIRWAY;

TURBULENCE MODELS;

AIRWAY PRESSURE; ARTICLE; BREATHING PATTERN; COMPUTER ASSISTED TOMOGRAPHY; EXHALATION; HORSE; HUMAN; IMAGE RECONSTRUCTION; INHALATION; MATHEMATICAL COMPUTING; MUSCLE CONTRACTION; NASOPHARYNX; NONHUMAN; RESPIRATORY AIRFLOW; SIMULATION; SOFT PALATE; TURBULENT FLOW; UPPER RESPIRATORY TRACT; VALIDATION PROCESS; AIRWAY RESISTANCE; ANIMAL; AUDIOVISUAL EQUIPMENT; BIOLOGICAL MODEL; BREATHING MECHANICS; COMPARATIVE ANATOMY; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; FLOW KINETICS; HISTOLOGY; KINETICS; MUSCLE STRENGTH; NONLINEAR SYSTEM; PHARYNX; PHYSIOLOGY; PRESSURE;

EQUIDAE;

AIRWAY RESISTANCE; ANATOMY, COMPARATIVE; ANIMALS; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; HORSES; HUMANS; KINETICS; MATHEMATICAL COMPUTING; MODELS, ANATOMIC; MODELS, BIOLOGICAL; MUSCLE STRENGTH; NONLINEAR DYNAMICS; PHARYNX; PHYSIOLOGY, COMPARATIVE; PRESSURE; RESPIRATORY MECHANICS; RHEOLOGY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 46749142106     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2913338     Document Type: Article

References (43)

1. Woakes, A. J., Butler, P. J., and Snow, D. H., 1987, "The Measurement of Respiratory Airflow in Exercising Horses," Equine Exercise Physiology 2: Proceedings of the Second International Conference on Equine Exercise Physiology, J. R. Gillespie and N. E. Robinson, eds., ICEEP, Davis, CA, pp. 194-205.
2. Nielan, G. J., Rehder, R. S., Ducharme, N. G., and Hackett, R. P., 1992, "Measurement of Tracheal Static Pressure in Exercising Horses," Vet. Surg., 21, pp. 423-428.
3. Derksen, F. J., Stick, J. A., Scott, E. A., Robinson, N. E., and Slocombe, R. F., 1986, "Effect of Laryngeal Hemiplegia and Laryngoplasty on Airway Flow Mechanics in Exercising Horses," Am. J. Vet. Res., 47, pp. 16-20.
4. Elad, D., Liebenthal, R., Wenig, B. L., and Einav, S., 1993, "Analysis of Air-Flow Patterns in the Human Nose," Med. Biol. Eng. Comput., 31, pp. 585-592.
5. Keyhani, K., Scherer, P. W., and Mozell, M. M., 1995, "Numerical Simulation of Airflow in the Human Nasal Cavity," J. Biomech. Eng., 117, pp. 429-441.
6. Alipour, F., Scherer, R., and Knowles, J., 1996, "Velocity Distributions in Glottal Models," J. Voice, 10, pp. 50-58.
7. Martonen, T. B., Quan, L., Zhang, Z. Q., and Musante, C. J., 2002, "Flow Simulation in the Human Upper Respiratory Tract," Cell Biochem. Biophys., 37, pp. 27-36.
8. Hahn, I., Scherer, P. W., and Mozell, M. M., 1993, "Velocity Profiles Measured for Air-Flow Through a Large-Scale Model of the Human Nasal Cavity," J. Appl. Physiol., 75, pp. 2273-2287.
9. Renotte, C., Bouffioux, V., and Wilquem, F., 2000, "Numerical 3d Analysis of Oscillatory Flow in the Time-Varying Laryngeal Channel," J. Biomech., 33, pp. 1637-1644.
10. Pope, S. B., 2000, Turbulent Flows, Cambridge University Press, Cambridge.
11. Allen, G. M., Shortall, B. P., Gemci, T., Corcoran, T. E., and Chigier, N. A., 2004, "Computational Simulations of Airflow in an In Vitro Model of the Pediatric Upper Airways," J. Biomech. Eng., 126, pp. 604-613.
12. Lindemann, J., Keck, T., Wiesmiller, K., Sander, L., Brambs, H. J., Rettinger, G., and Pless, D., 2004, "A Numerical Simulation of Intranasal Air Temperature During Inspiration," Laryngoscope, 114, pp, 1037-1041.
13. Pless, D., Keck, T., Wiesmiller, K., Rettinger, G., Aschoff, A. J., Fleiter, T. R., and Lindemann, J., 2004, "Numerical Simulation of Air Temperature and Airflow Patterns in the Human Nose During Expiration," Clin. Otolaryngol., 29, pp. 642-647.
14. Kleinstreuer, C., and Zhang, Z., 2003, "Laminar-to-Turbulent Fluid-Particle Flows in a Human Airway Model," Int. J. Multiphase Flow, 29, pp. 271-289.
15. Zhang, Z., and Kleinstreuer, C., 2004, "Airflow Structures and Nano-Particle Deposition in a Human Upper Airway Model," J. Comput. Phys., 198, pp. 178-210.
16. Lindemann, J., Brambs, H. J., Keck, T., Wiesmiller, K. M., Rettinger, G., and Pless, D., 2005, "Numerical Simulation of Intranasal Airflow After Radical Sinus Surgery," Am. J. Otolaryngol., 26, pp. 175-180.
17. Alipour, F., and Scherer, R. C., 2004, "Flow Separation in a Computational Oscillating Vocal Fold Model," J. Acoust. Soc. Am., 116, pp. 1710-1719.
18. Girardin, M., Bilgen, E., and Arbour, P., 1983, "Experimental-Study of Velocity-Fields in a Human Nasal Fossa by Laser Anemometry," Ann. Otol. Rhinol. Laryngol., 92, pp. 231-236.
19. Art, T., and Lekeux, P., 1989, "Work of Breathing in Exercising Ponies," Res. Vet. Sci., 46, pp. 49-53.
20. Guyton, A. C., and Hall, J. F., 1996, Textbook of Medical Physiology, Saunders, Philadelphia, PA.
21. Savard, P., Cole, P., Miljeteig, H., and Haight, J. S. J., 1993, "Laryngeal Resistance to Respiratory Air-Flow in Humans," Laryngoscope, 103, pp. 785-792.
22. Auer, J. A., and Stick, J. A., 2006, Equine Surgery, 3rd ed., Saunders Elsevier, St. Louis, MO.
23. Cole, P., 1992, The Respiratory Role of the Upper Airways, Mosby Year Book, St. Louis, MO.
24. Tetens, J., Derksen, F. J., Stick, J. A., Lloyd, J. W., and Robinson, N. E., 1996, "Efficacy of Prosthetic Laryngoplasty With and Without Bilateral Ventriculocordectomy as Treatments for Laryngeal Hemiplegia in Horses," Am. J. Vet. Res., 57, pp. 1668-1673.
25. Musante, C. J., and Martonen, T. B., 2000, "Computer Simulations of Particle Deposition in the Developing Human Lung," J. Air Waste Manage. Assoc., 50, pp. 1426-1432.
26. Corcoran, T. E., and Chigier, N., 2000, "Characterization of the Laryngeal Jet Using Phase Doppler Interferometry," J. Aerosol Med., 13(2), pp. 125-137.
27. Getty, R., 1975, The Anatomy of the Domestic Animals, 5th ed., Saunders Co., Philadelphia, PA.
28. Radcliffe, C. H., Woodie, J. B., Hackett, R. P., Ainsworth, D. M., Erb, H. N., Mitchell, L. M., Soderholm, L. V., and Ducharme, N. G., 2006, "A Comparison of Laryngoplasty and Modified Partial Arytenoidectomy as Treatments for Laryngeal Hemiplegia in Exercising Horses," Vet. Surg., 35, pp. 643-652.
29. Xu, C., Sin, S. H., McDonough, J. M., Udupa, J. K., Guez, A., Arens, R., and Wootton, D. M., 2006, "Computational Fluid Dynamics Modeling of the Upper Airway of Children With Obstructive Sleep Apnea Syndrome in Steady Flow," J. Biomech., 39, pp. 2043-2054.
30. Haynes, P. F., 1983, "Dorsal Displacement of the Soft Palate and Epiglottic Entrapment - Diagnosis, Management, and Interrelationship," Comp. Cont. Educ. Pract. Vet, 5(7), pp. S379-S388.
31. Davidson, T. M., 2003, "The Great Leap Forward: The Anatomic Basis for the Acquisition of Speech and Obstructive Sleep Apnea," Sleep Med., 4(3), pp. 185-194.
32. Sforza, E., Krieger, J., and Petiau, C., 1998, "Nocturnal Evolution of Respiratory Effort in Obstructive Sleep Apnoea Syndrome: Influence on Arousal Threshold," Eur. Respir. J., 12, pp. 1257-1263.
33. Wang, W., Verin, E., and Series, F., 2006, "Influences of the Breathing Route on Upper Airway Dynamics Properties in Normal Awake Subjects With Constant Mouth Opening," Clin. Sci., 111, pp. 349-355.
34. Younes, M., Sanii, R., Patrick, W., Marantz, S., and Webster, K., 1994, "An Approach to the Study of Upper Airway Function in Humans," J. Appl. Physiol., 77, pp. 1383-1392.
35. Schwartz, A. R., Smith, P. L., Wise, R. A., Gold, A. R., and Permutt, S., 1988, "Induction of Upper Airway Occlusion in Sleeping Individuals With Subatmospheric Nasal Pressure," J. Appl. Physiol., 64, pp. 535-542.
36. Kairaitis, K., Byth, K., Parikh, R., Stavrinou, R., Wheatley, J. R., and Amis, T. C., 2007, "Tracheal Traction Effects on Upper Airway Patency in Rabbits: The Role of Tissue Pressure," Sleep, 30, pp. 179-186.
37. Gehr, P., Hof, V. I., Geiser, M., and Schurch, S., 1991, "The Fate of Particles Deposited in the Intrapulmonary Conducting Airways," J. Aerosol Med., 4(4), pp. 349-361.
38. McKenzie, H. C., 2003, "Characterization of Antimicrobial Aerosols for Administration to Horses," Vet. Ther., 4(2), pp. 110-119.
39. Martonen, T. B., Zhang, Z., Yue, G., and Musante, C. J., 2002, "3-D Particle Transport Within the Human Upper Respiratory Tract," J. Aerosol Sci., 33, pp. 1095-1110.
40. Wheeler, E. F., Diehl, N. K., Zajaczkowski, J. L., and Brown, D., 2006, "Particulate Matter Characterization in Equestrian Riding Arenas," Trans. ASABE, 49, pp. 1529-1538.
41. Davis, M. S., and Foster, W. M., 2001, "Airflow and Device Effects on Aerosol Delivery for Large Animals," J. Vet. Pharmacol. Ther., 24, pp. 57-60.
42. Kidd, J. A., and Slone, D. E., 2002, "Treatment of Laryngeal Hemiplegia in Horses by Prosthetic Laryngoplasty, Ventriculectomy and Vocal Cordectomy," Vet. Rec., 150, pp. 481-484.
43. Huang, Y. Q., Malhotra, A., and White, D. P., 2005, "Computational Simulation of Human Upper Airway Collapse Using a Pressure-/State-Dependent Model of Genioglossal Muscle Contraction Under Laminar Flow Conditions," J. Appl. Physiol., 99, pp. 1138-1148.