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Volumn 623, Issue 2, 2008, Pages 221-230
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A study of the analytical behaviour of selected new molecular entities using electrospray ionisation ion trap mass spectrometry, liquid chromatography, gas chromatography and polarography and their determination in serum at therapeutic concentrations
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Author keywords
Differential pulse polarography; Electrospray ionisation ion trap mass spectrometry; Gas liquid chromatography flame ionisation detection; Liquid chromatography electrospray ionisation ion trap mass spectrometry; New molecular entities; Serum analysis
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Indexed keywords
BODY FLUIDS;
CHARGED PARTICLES;
CHEMICALS;
CHEMOTHERAPY;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
DRUG DELIVERY;
DRUG DOSAGE;
ELECTRONS;
ELECTROSPRAY IONIZATION;
GAS CHROMATOGRAPHY;
HEALTH;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
ION CHROMATOGRAPHY;
IONIZATION;
IONIZATION OF LIQUIDS;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
MOLECULES;
SPECTROMETERS;
SPECTROMETRY;
SPECTRUM ANALYSIS;
ANTI CANCER DRUGS;
ANTIRETROVIRAL DRUGS;
CHEMICAL INFORMATION;
ELECTROSPRAY (ES);
EMTRICITABINE;
GEFITINIB;
ION-TRAP MASS SPECTROMETRY;
MOLECULAR ENTITIES;
NEUROLOGICAL DISORDERS;
QUADRUPOLE ION TRAP MASS SPECTROMETRY;
DRUG THERAPY;
ACETONITRILE;
ANTIINFECTIVE AGENT;
ANTINEOPLASTIC AGENT;
ANTIRETROVIRUS AGENT;
APREPITANT;
ATAZANAVIR;
DIAZEPAM;
EMTRICITABINE;
GEFITINIB;
GEMIFLOXACIN;
HYPOCHOLESTEROLEMIC AGENT;
INDINAVIR;
ROSUVASTATIN;
ACCURACY;
ARTICLE;
CONTROLLED STUDY;
DIFFERENTIAL PULSE POLAROGRAPHY;
DRUG BLOOD LEVEL;
DRUG STRUCTURE;
ELECTROSPRAY MASS SPECTROMETRY;
FOOD AND DRUG ADMINISTRATION;
GAS CHROMATOGRAPHY;
HUMAN;
ION TRAP MASS SPECTROMETRY;
LIQUID CHROMATOGRAPHY;
MALE;
MOLECULAR WEIGHT;
NEOPLASM;
PRECIPITATION;
PRIORITY JOURNAL;
REPRODUCIBILITY;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
ACETONITRILES;
CHROMATOGRAPHY, GAS;
CHROMATOGRAPHY, LIQUID;
DRUG THERAPY;
FLAME IONIZATION;
HETEROCYCLIC COMPOUNDS, 1-RING;
HUMANS;
MOLECULAR WEIGHT;
PHARMACEUTICAL PREPARATIONS;
POLAROGRAPHY;
PRECIPITATION;
PROTEINS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
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EID: 46749134220
PISSN: 00032670
EISSN: None
Source Type: Journal
DOI: 10.1016/j.aca.2008.06.025 Document Type: Article |
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Times cited : (32)
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References (29)
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