Three-dimensional solution structure of EM703 with potent promoting activity of monocyte-to-macrophage differentiation

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 9, 2006, Pages 2496-2499

  Gouda, Hiroaki ^a   Sunazuka, Toshiaki ^a,b   Yoshida, Kiminari ^a   Sugawara, Akihiro ^a   Sakoh, Yusuke ^a   Omura, Satoshi ^a,b   Hirono, Shuichi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b KITASATO INSTITUTE   (Japan)

Author keywords

Alignment; Erythromycin A; Erythromycin derivative; Immunomodulatory activity; Molecular dynamics; NMR; QSAR; Three dimensional solution structure

Indexed keywords

EM 703; EM703; ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; CELL DIFFERENTIATION; DRUG POTENCY; IN VITRO STUDY; MACROPHAGE; MONOCYTE; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

CELL DIFFERENTIATION; DRUG EVALUATION, PRECLINICAL; ERYTHROMYCIN; HUMANS; HYDROGEN BONDING; IMAGING, THREE-DIMENSIONAL; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MONOCYTES; SOLUTIONS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644974199     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.079     Document Type: Article

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