Molecular MRI of hematopoietic stem-progenitor cells: In vivo monitoring of gene therapy and atherosclerosis

Nature Clinical Practice Cardiovascular Medicine

Volumn 5, Issue 7, 2008, Pages 396-404

  Qiu, Bensheng ^a   Yang, Xiaoming ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM TEXAPHYRIN; GREEN FLUORESCENT PROTEIN; SCATTER FACTOR; SUPERPARAMAGNETIC IRON OXIDE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; VASCULOTROPIN;

ARTERY INJURY; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL HOMING; CELL LABELING; CELL MIGRATION; CELLULAR DISTRIBUTION; EARLY DIAGNOSIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEMATOPOIETIC STEM CELL; HUMAN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVIEW; STEM CELL GENE THERAPY; TREATMENT PLANNING;

ATHEROSCLEROSIS; GENE THERAPY; HEMATOPOIETIC STEM CELLS; HUMANS; MAGNETIC RESONANCE IMAGING;

EID: 46649121666     PISSN: 17434297     EISSN: 17434300     Source Type: Journal    
DOI: 10.1038/ncpcardio1217     Document Type: Review

References (50)

1. Heart Disease and Stroke Statistics Update [http://www.americanheart.org/ presenter.jhtml?identifier=1928]
2. Raines EW (2000) The extracellular matrix can regulate vascular cell migration, proliferation, and survival: Relationships to vascular disease. Int J Exp Pathol 81: 173-182
3. Ross R (1996) Genetically modified mice as models of transplant atherosclerosis. Nat Med 2: 527-528
4. Ross R (1999) Atherosclerosis - an inflammatory disease. N Engl J Med 340: 115-126
5. Kearney M et al. (1997) Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation 95: 1998-2002
6. Billingham ME (1987) Cardiac transplant atherosclerosis. Transplant Proc 19: 19-25
7. Libby P (2002) Inflammation in atherosclerosis. Nature 420: 868-874
8. Tricot O et al. (2000) Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 101: 2450-2453
9. Sata M et al. (2002) Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 8: 403-409
10. Saiura A et al. (2001) Circulating smooth muscle progenitor cells contribute to atherosclerosis. Nat Med 7: 382-383
11. Shi Q et al. (1998) Evidence for circulating bone marrow-derived endothelial cells. Blood 92: 362-367
12. Modo M et al. (2005) Cellular MR imaging. Mol Imaging 4 143-164
13. Bulte JW et al. (1994) Magnetoferritin: Characterization of a novel superparamagnetic MR contrast agent. J Magn Reson Imaging 4: 497-505
14. Bulte JW and Kraitchman DL (2004) Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed 17: 484-499
15. Vymazal J et al. (1993) Frequency dependence of MR relaxation times. I. Paramagnetic ions. J Magn Reson Imaging 3: 637-640
16. Bulte JW et al. (2001) Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells. Nat Biotechnol 19 1141-1147
17. Daldrup-Link H et al. (2003) Targeting of hematopoietic progenitor Galls with MR contrast agents. Radiology 228: 760-767
18. Daldrup-Link HE et al. (2004) Cell tracking with gadophrin-2: A bifunctional contrast agent for MR imaging, optical imaging, and fluorescence microscopy. EurJ Nucl Med Mol Imaging 31: 1312-1321
19. Young SW et al. (1994) Preclinical evaluation of gadolinium (III) texaphyrin complex: A new paramagnetic contrast agent for magnetic resonance imaging. Invest Radiol 29: 330-338
20. Woodburn K (2001) Intracellular localization of the radiation enhancer motexafin gadolinium using interferometric Fourier fluorescence microscopy. J Pharmacol Exp Ther 297: 888-894
21. Hoehn M et al. (2002) Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA 99: 16267-16272
22. Frank JA et al. (2003) Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents. Radiology 228: 480-487
23. Arbab AS et al. (2004) Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 104: 1217-1223
24. Bulte JW et al. (2004) Preparation of magnetically labeled cells for cell tracking by magnetic resonance imaging. Methods Enzymol 386: 275-299
25. Gan WB et al. (2000) Multicolor "DIOlistic" labeling of the nervous system using lipophilic dye combinations. Neuron 27: 219-225
26. Zhang ZG et al. (2003) Magnetic resonance imaging and neurosphere therapy of stroke in rat. Ann Neurol 53: 259-263
27. Walczak P et al. (2005) Instant MR labeling of stem cells using magnetoelectroporation. Magn Reson Med 54: 769-774
28. Liu J et al. (1998) Non-invasive assessment and control of ultrasound-mediated membrane permeabilization. Pharm Res 15: 918-924
29. Han YW et al. (2007) Sonoporation is an efficient tool for intracellular fluorescent dextran delivery and one-step double-crossover mutant construction in Fusobacterium nucleatum. Appl Environ Microbiol 73: 3677-3683
30. Schlicher RK et al. (2006) Mechanism of intracellular delivery by acoustic cavitation. Ultrasound Med Biol 32: 915-924
31. Zarnitsyn VG and Prausnitz MR (2004) Physical parameters influencing optimization of ultrasound-mediated DNA transfection. Ultrasound Med Biol 30. 527-538
32. Dinno MA et al. (11989) The effect of therapeutic ultrasound on electrophysiological parameters of frog skin. Ultrasound Med Biol 15: 461-470
33. Kim HJ et al. (1996) Ultrasound-mediated transfection of mammalian cells. Hum Gene Ther 7: 1339-1346
34. Miller DL et al. (2002) Sonoporation: Mechanical DNA delivery by ultrasonic cavitation. Somat Cell Mol Genet 27: 115-134
35. Newman C et al. (2001) Ultrasound gene therapy: On the road from concept to reality. Echocardiography 18: 339-347
36. Krause DS et al. (2001) Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105: 369-377
37. Wagner J et al (2002) A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies. Hum Gene Ther 13: 1349-1359
38. Gao F et al. (2007) MRI of intravenously injected bone marrow cells homing to the site of injured arteries. NMR Biomed 20: 673-681
39. Sata M (2003) Circulating vascular progenitor cells contribute to vascular repair, remodeling, and lesion formation. Trends Cardiovasc Med 13: 249-253
40. Qiu B et al. (2007) in vivo MR imaging of bone marrow cells trafficking to atherosclerotic plaques. J Magn Reson Imaging 26 339-343
41. Nabel E and Leiden J (11999) Gene transfer approaches for cardiovascular disease. In Molecular Basis of cardiovascular disease, 86-112 (Ed. Chien K) Philadelphia: WB Saunders
42. Yla-Herttuala S and Martin J (2000) Cardiovascular gene therapy. Lancet 355: 213-222
43. Losordo D et al. (2003) Endothelial recovery: The next target in restenosis prevention. Circulation 107: 2635-2637
44. Yang X (2003) Imaging of vascular gene therapy. Radiology 228 36-49
45. Yang X and Atalar E (2006) MRI-guided gene therapy. FEBS Lett 580: 2958-2961
46. Deux JF et al. (2007) Aortic aneurysms in a rat model: in vivo MR imaging of endovascular cell therapy. Radiology 246: 185-192
47. Oude Engberink RD et al. (2007) Comparison of SPIO and USPIO for in vitro labeling of human monocytes: MR detection and cell function. Radiology 243: 467-474
48. Walczak P et al. (2006) Magnetoelectroporation: Improved labeling of neural stem cells and leukocytes for cellular magnetic resonance imaging using a single FDA-approved agent. Nanomedicine 2: 89-94
49. de-Vries I et al. (2005) Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 23: 1407-1413
50. Zhu J et al. (2006) Tracking neural stem cells in patients with brain trauma. N Engl J Med 355: 2376-2378