The 5 × 5 Gy with delayed surgery in non-resectable rectal cancer: A new treatment option

Radiotherapy and Oncology

Volumn 87, Issue 3, 2008, Pages 311-313

  Bujko, Krzysztof ^a   Kolodziejczyk, Milena ^a  

^a INSTITUTE OF ONCOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL CRAMP; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; EDITORIAL; FOLLOW UP; HUMAN; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RECTUM CANCER; THERAPY DELAY; TREATMENT RESPONSE; ADJUVANT THERAPY; NOTE; RADIATION DOSE; RECTUM TUMOR;

DOSE FRACTIONATION; HUMANS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS;

EID: 46549084338     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2007.12.020     Document Type: Editorial

References (24)

1. Basha G., Landuyt W., Fowler J., et al. An experimental evaluation of three preoperative radiation regimens for resectable rectal cancer. Ann Surg Oncol 9 (2002) 292-297
2. Birgisson H., Pahlman L., Gunnarsson U., and Glimelius B. Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol 23 (2005) 8697-8705
3. Bosset J.F., Collette L., Calais G., et al. Chemoradiotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 355 (2006) 1114-1123
4. Braendengen M., Tveit K.M., Berglund A., et al. A randomised phase III study (LARCS) comparing preoperative radiotherapy alone versus chemoradiotherapy in non-resectable rectal cancer. Eur J Cancer Suppl 3/2 (2005) 172 [abstr.]
5. Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D., and Armour E.P. Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue. Int J Radiat Oncol Biol Phys 52 (2002) 6-13
6. Bujko K., Nowacki M.P., Nasierowska-Guttmejer A., et al. Long-term results of randomized trial comparing preoperative short-course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer. Br J Surg 93 (2006) 1215-1223
7. Bujko K., Nowacki M.P., Nasierowska-Guttmejer A., et al. Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomized trial comparing short-term radiotherapy vs conventionally fractionated radiochemotherapy. Radiother Oncol 72 (2004) 15-24
8. Colorectal Cancer Collaborative Group. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials. Lancet 2001;358:1291-304.
9. Dewar J.A., Haviland J.S., Agrawal R.K., et al. Hypofractionation for early breast cancer: first results of the UK standardization of breast radiotherapy (START) trials. J Clin Oncol 25 (2007) [18S (abstr.)]
10. Folkesson J., Birgisson H., Pahlman L., Cedermark B., Glimelius B., and Gunnarsson U. Swedish Rectal Cancer Trial: long lasting benefits from radiotherapy on survival and local recurrence rate. J Clin Oncol 23 (2005) 5644-5650
11. Frykholm G.J., Glimelius B., and Pahlman L. Preoperative or postoperative irradiation in adenocarcinoma of the rectum: final treatment results of a randomized trial and evaluation of late secondary effects. Dis Colon Rectum 36 (1993) 564-572
12. Francois Y., Nemoz C.J., Bauliex J., et al. Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: The Lyon R90-01 randomized trial. J Clin Oncol 17 (1999) 2396-2402
13. Gerard J.P., Conroy T., Bonnetain F., et al. Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: results of FFCD 9203. J Clin Oncol 24 (2006) 4620-4625
14. Hartley A., Giridharan S., Srihari N., McConkey C., and Geh J.I. Impaired postoperative neutrophil leucocytosis and acute complications following short course preoperative radiotherapy for operable rectal cancer. Eur J Surg Oncol 29 (2003) 155-157
15. Lievens Y., Van den Bogaert W., Rijnders A., Kutcher G., and Kesteloot K. Palliative radiotherapy practice within Western European countries: impact of the radiotherapy financing system?. Radiother Oncol 56 (2000) 289-295
16. Marijnen C.A., Nagtegaal I.D., Klein Kranenbarg E., et al. No downstaging after short-term preoperative radiotherapy in rectal cancer patients. J Clin Oncol 19 (2001) 1976-1984
17. Peeters K.C., Marijnen C.A., Nagtegaal I.D., et al. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg 246 (2007) 693-701
18. Pietrzak L., Bujko K., Nowacki M.P., et al. Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomised trial. Radiother Oncol 84 (2007) 217-225
19. Radu C., Berglund A., Pahlman L., and Glimelius B. Short course preoperative radiotherapy with delayed surgery in rectal cancer - a retrospective study. Radiother Oncol 87 (2008) 343-349
20. Sauer R., Becker H., Hohenberger W., et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351 (2004) 1731-1740
21. Sebag-Montfiore D., Steele R., Quike P., et al. Short-course preoperative radiotherapy results improves outcome when compared with highly selective postoperative radiochemotherapy. Preliminary results of the MRC CR07 randomised trial. Radiother Oncol 81 (2006) s19 [abstr.]
22. Suwinski R., Taylor J.M., and Withers H.R. Rapid growth of microscopic rectal cancer as a determinant of response to preoperative radiation therapy. Int J Radiat Oncol Biol Phys 42 (1998) 943-951
23. Suwinski R., Wzietek I., Tarnawski R., et al. Moderately low alpha/beta ratio for rectal cancer may best explain the outcome of three fractionation schedules of preoperative radiotherapy. Int J Radiat Oncol Biol Phys 69 (2007) 793-799
24. Widder J., Herbst F., and Scheithauer W. Preoperative sequential short-term radiotherapy plus chemotherapy can induce complete remission in T3N2 rectal cancer. Acta Oncol 44 (2005) 921-923