Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network

Microcirculation

Volumn 15, Issue 3, 2008, Pages 191-202

  Warren, Alessandra ^a   Chaberek, Slawomir ^b   Ostrowski, Kazimierz ^c   Cogger, Victoria C ^a   Hilmer, Sarah N ^d   Mccuskey, Robert S ^e   Fraser, Robin ^f   Le Couteur, David G ^a  

^a ANZAC Research Institute   (Australia)

^b Department of Rehabilitation   (Poland)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Aging; Fourier analysis; Fractal dimensions; Liver; Liver sinusoid; Microcirculation; Multiple indicator dilution; Vascular casts; Vascular dispersion

Indexed keywords

AGING; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CAPILLARY; FISCHER 344 RAT; FOURIER ANALYSIS; FRACTAL ANALYSIS; HISTOLOGY; LIVER; LIVER CIRCULATION; MALE; MICROCIRCULATION; PHYSIOLOGY; RAT; SCANNING ELECTRON MICROSCOPY; ULTRASTRUCTURE; VASCULARIZATION;

AGING; ANIMALS; CAPILLARIES; CORROSION CASTING; FOURIER ANALYSIS; FRACTALS; LIVER; LIVER CIRCULATION; MALE; MICROCIRCULATION; MICROSCOPY, ELECTRON, SCANNING; MODELS, CARDIOVASCULAR; RATS; RATS, INBRED F344;

EID: 46449125423     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1080/10739680701600856     Document Type: Article

References (57)

1. Bassingthwaighte JB, King RB, Roger SA. (1989). Fractal nature of regional myocardial blood flow heterogeneity. Circ Res 65:578-590.
2. Bassingthwaighte JB, King RB, Sambrook JE, van Steenwyk B. (1988). Fractal analysis of bloodtissue exchange kinetics. Adv Exp Med Biol 222:15-23.
3. Bearden SE. (2006). Effect of aging on the structure and function of skeletal muscle microvascular networks. Microcirculation 13:279-288.
4. Bearden SE, Payne GW, Chisty A, Segal SS. (2004). Arteriolar network architecture and vasomotor function with ageing in mouse gluteus maximus muscle. J Physiol 561:535-545.
5. Brouwer A, Barelds RJ, Knook DL. (1985). Agerelated changes in the endocytic capacity of rat liver Kupffer and endothelial cells. Hepatology 5:362-366.
6. Chelminiak P, Dixon JM, Tuszynski JA, Marsh RE. (2006). Application of a random network with a variable geometry of links to the kinetics of drug elimination in healthy and diseased livers. Phys Rev E Stat Nonlin Soft Matter Phys 73:051912.
7. Cogger VC, Hilmer S, Sullivan D, Muller M, Fraser R, Le Couteur DG. (2006). Surfactants and hyperlipidemia: the liver sieve is a link. Atherosclerosis 189:273-281.
8. Cogger VC, Warren A, Fraser R, Ngu M, McLean AJ, Le Couteur DG. (2003). Hepatic sinusoidal pseudocapillarization with aging in the non-human primate. Exp Gerontol 38:1101-1107.
9. Cook JJ, Wailgum TD, Vasthare US, Mayrovitz HN, Tuma RF. (1992). Age-related alterations in the arterial microvasculature of skeletal muscle. J Gerontol 47:B83-B88.
10. Cross SS, Start RD, Silcocks PB, Bull AD, Cotton DW, Underwood JC. (1993). Quantitation of the renal arterial tree by fractal analysis. J Pathol 170:479-484.
11. Evans AM, Hussein Z, Rowland M. (1991). A twocompartment dispersion model describes the hepatic outflow profile of diclofenac in the presence of its binding protein. J Pharm Pharmacol 43:709-714.
12. Farkas E, Luiten PG. (2001). Cerebral microvascular pathology in aging and Alzheimer's disease. Prog Neurobiol 64:575-611.
13. Folkow B, Svanborg A. (1993). Physiology of cardiovascular aging. Physiol Rev 73:725-764.
14. Froomes PR, Sachinidis J, Ghabrial H, Tochon-Danguy H, Scott A, Ching MS, et al. (2003). A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using [15O]O2. Nucl Med Biol 30:93-100.
15. Fuite J, Marsh R, Tuszynski J. (2002). Fractal pharmacokinetics of the drug mibefradil in the liver. Phys Rev E Stat Nonlin Soft Matter Phys 66:021904.
16. Gaudio E, Chaberek S, Montella A, Pannarale L, Morini S, Novelli G, et al. (2005). Fractal and Fourier analysis of the hepatic sinusoidal network in normal and cirrhotic rat liver. J Anat 207:107-115.
17. Ghirardi O, Cozzolino R, Guaraldi D, Giuliani A. (1995). Within-and between-strain variability in longevity of inbred and outbred rats under the same environmental conditions. Exp Gerontol 30:485-494.
18. Goldberger AL, Amaral LA, Hausdorff JM, Ivanov P, Peng CK, Stanley HE. (2002). Fractal dynamics in physiology: alterations with disease and aging. Proc Natl Acad Sci U S A 99(Suppl 1):2466-2472.
19. Goldberger AL, Peng CK, Lipsitz LA. (2002). What is physiologic complexity and how does it change with aging and disease? Neurobiol Aging 23:23-26.
20. Goresky CA, Pang KS, Schwab AJ, Barker Fd, Cherry WF, Bach GG. (1992). Uptake of a protein-bound polar compound, acetaminophen sulfate, by perfused rat liver. Hepatology 16:173-190.
21. Harman D. (1956). Aging: a theory based on free radical and radiation chemistry. J Gerontol 11: 298-300.
22. Hilmer SN, Cogger VC, Fraser R, McLean AJ, Sullivan D, Le Couteur DG. (2005). Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat. Hepatology 42:1349-1354.
23. Huet PM, Villeneuve JP. (2005). Microcirculation of the aging liver: is getting old like having cirrhosis? Hepatology 42:1248-1251.
24. Ito Y, Sorensen KK, Bethea NW, Svistounov D, Mc-Cuskey MK, Smedsrod BH, et al. (2007). Age-related changes in the hepatic microcirculation of mice. Exp Gerontol 48:789-797.
25. Jamieson H, Hilmer SN, Cogger VC, Warren A, Cheluvappa R, Abernethy DR, et al. (2007). Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid. Exp Gerontol 42:374-378.
26. Javanaud C. (1989). The application of a fractal model to the scattering of ultrasound in biological media. J Acoust Soc Am 86:493-496.
27. Krucker T, Lang A, Meyer EP. (2006). New polyurethane-based material for vascular corrosion casting with improved physical and imaging characteristics. Microsc Res Tech 69:138-147.
28. Kyriazis M. (2003). Practical applications of chaos theory to the modulation of human ageing: nature prefers chaos to regularity. Biogerontology 4:75-90.
29. Lakatta EG. (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises:.Part III: cellular and molecular clues to heart and arterial aging. Circulation 107:490-497.
30. Lakatta EG, Levy D. (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation 107:139-146.
31. Landini G, Misson GP, Murray PI. (1993). Fractal analysis of the normal human retinal fluorescein angiogram. Curr Eye Res 12:23-27.
32. Le Couteur DG, Cogger VC, Markus AMA, Harvey PJ, Yin ZL, Ansselin AD, et al. (2001). Pseudocapillarization and associated energy limitation in the aged rat liver. Hepatology 33:537-543.
33. Le Couteur DG, Fraser R, Cogger VC, McLean AJ. (2002). Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet 359:1612-1615.
34. Le Couteur DG, Fraser R, Hilmer S, Rivory LP, McLean AJ. (2005). The hepatic sinusoid in aging and cirrhosis-effects on hepatic substrate disposition and drug clearance. Clin Pharmacokinet 44:187-200.
35. Le Couteur DG, McLean AJ. (1998). The aging liver-drug clearance and an oxygen diffusion barrier hypothesis. Clin Pharmacokinet 34:359-373.
36. Le Couteur DG, Rivory LP, Pond SM. (1993). Hepatic intracellular pH during the prereplicative period following partial hepatectomy. Am J Physiol 264:G767-G773.
37. Le Couteur DG, Warren A, Cogger VC, Smedsrod B, Sorensen K, de Cabo R, et al. (2007). Old age and the hepatic sinusoid. Anatom Rec (in press).
38. Lipsitz LA, Goldberger AL. (1992). Loss of "complexity" and aging. Potential applications of fractals and chaos theory to senescence. JAMA 267:1806-1809.
39. Macheras P. (1996). A fractal approach to heterogeneous drug distribution: calcium pharmacokinetics. Pharm Res 13:663-670.
40. Marin J. (1995). Age-related changes in vascular responses: a review. Mech Ageing Dev 79:71-114.
41. Marxen M, Henkelman RM. (2003). Branching tree model with fractal vascular resistance explains fractal perfusion heterogeneity. Am J Physiol 284:H1848-H1857.
42. Masters BR. (2004). Fractal analysis of the vascular tree in the human retina. Annu Rev Biomed Eng 6:427-452.
43. McLean AJ, Cogger VC, Chong GC, Warren A, Markus AMA, Dahlstrom JE, et al. (2003). Age-related pseudocapillarization of the human liver. J Pathol 200:112-117.
44. McLean AJ, Le Couteur DG. (2004). Aging biology and geriatric clinical pharmacology. Pharmacol Rev 56:163-184.
45. Payne GW, Bearden SE. (2006). The microcirculation of skeletal muscle in aging. Microcirculation 13:275-277.
46. Poole D, Behnke B, Musch T. (2006). Capillary hemodynamics and oxygen pressures in the aging microcirculation. Microcirculation 13:289-299.
47. Riddle DR, Sonntag WE, Lichtenwalner RJ. (2003). Microvascular plasticity in aging. Ageing Res Rev 2:149-168.
48. Roberts MS, Donaldson JD, Rowland M. (1988). Models of hepatic elimination: comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination. J Pharmacokinet Biopharm 16: 31-83.
49. Roberts MS, Rowland M. (1986). A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations. J Pharmacokinet Biopharm 14:227-260.
50. Sahin S, Rowland M. (2000). Evaluation of route of input on the hepatic disposition of diazepam. J Pharmacol Exp Ther 295:836-843.
51. Schmucker DL. (2005). Age-related changes in liver structure and function: implications for disease? Exp Gerontol 40:650-659.
52. Schmucker DL. (1998). Aging and the liver: an update. J Gerontol 53A:B315-B320.
53. Vollmar B, Pradarutti S, Richter S, Menger MD. (2002). In vivo quantification of ageing changes in the rat liver from early juvenile to senescent life. Liver 22:330-341.
54. Warren A, Bertolino P, Cogger VC, McLean AJ, Fraser R, Le Couteur DG. (2005). Hepatic pseudocapillarization in aged mice. Exp Gerontol 40:807-812.
55. Weiss M. (1997). A note on the interpretation of tracer dispersion in the liver. J Theor Biol 184:1-6.
56. Weiss M, Ballinger LN, Roberts MS. (1998). Kinetic analysis of vascular marker distribution in perfused rat livers after regeneration following partial hepatectomy. J Hepatol 29:476-481.
57. Wynne H.A, Cope L.H, Mutch E, Rawlins M.D, Woodhouse K.W, James O.F.W. (1989). The effect of age upon liver volume and apparent liver blood flow in healthy man. Hepatology 9:297-301.