Polymethylmethacrylate particles inhibit osteoblastic differentiation of MC3T3-E1 osteoprogenitor cells

Journal of Orthopaedic Research

Volumn 26, Issue 7, 2008, Pages 932-936

  Chiu, Richard ^a   Ma, Ting ^a   Smith, R Lane ^a   Goodman, Stuart B ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Implant loosening; MC3T3 E1 cells; Osteoprogenitor differentiation; Polymethylmethacrylate; Wear debris particles

Indexed keywords

ALKALINE PHOSPHATASE; OSTEOCALCIN; POLY(METHYL METHACRYLATE);

ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; STEM CELL; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CELL STRAIN 3T3; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; JOINT PROSTHESIS; TIME;

3T3 CELLS; ANIMALS; CELL DIFFERENTIATION; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; JOINT PROSTHESIS; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOGENESIS; POLYMETHYL METHACRYLATE; TIME FACTORS;

EID: 46449111528     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20618     Document Type: Article

References (26)

1. Wright T, Goodman SB. 2001. Implant wear in total joint replacement. Illinois: American Academy of Orthopaedic Surgeons.
2. Okafor CC, Haleem-Smith H, Laqueriere P, et al. 2006. Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris. J Orthop Res 24:461-473.
3. Wang ML, Nesti LJ, Tuli R, et al. 2002. Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells. J Orthop Res 20:1175-1184.
4. Wang ML, Tuli R, Manner PA, et al. 2003. Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles. J Orthop Res 21:697-707.
5. Chiu R, Ma T, Smith RL, et al. 2006. Polymethylmethacrylate particles inhibit osteoblastic differentiation of bone marrow osteoprogenitor cells. J Biomed Mater Res A 77:850-856.
6. Chiu R, Ma T, Smith RL, et al. 2007. Kinetics of polymethylmethacrylate particle-induced inhibition of osteoprogenitor differentiation and proliferation. J Orthop Res 25:450-457.
7. Goodman SB, Ma T, Chiu R, et al. 2006. Effects of orthopaedic wear particles on osteoprogenitor cells: a review. Biomaterials 27:6096-6101.
8. Vermes C, Roebuck KA, Chandrasekaran R, et al. 2000. Particulate wear debris activates protein tyrosine kinases and nuclear factor κB, which down-regulates type I collagen synthesis in human osteoblasts. J Bone Miner Res 15:1756-1765.
9. Vermes C, Chandrasekaran R, Jacobs JJ, et al. 2001. The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts. J Bone Joint Surg Am 83-A:201-211.
10. Dean DD, Schwartz Z, Blanchard CR, et al. 1999. Ultrahigh molecular weight polyethylene particles have direct effects on proliferation, differentiation, and local factor production of MG63 osteoblast-like cells. J Orthop Res 17:9-17.
11. Dean DD, Schwartz Z, Liu Y, et al. 1999. The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitro. J Bone Joint Surg Am 81:452-461.
12. Zambonin G, Colucci S, Cantatore F, et al. 1998. Response of human osteoblasts to polymethylmethacrylate in vitro. Calcif Tissue Int 62:362-365.
13. Yao J, CS-Szabo G, Jacobs JJ, et al. 1997. Suppression of osteoblast function by titanium particles. J Bone Joint Surg Am 79-A:107-112.
14. Lohmann CH, Schwartz Z, Koster G, et al. 2000. Phagocytosis of wear debris by osteoblasts affects differentiation and local factor production in a manner dependent on particle composition. Biomaterials 21:551-561.
15. Lohmann CH, Dean DD, Koster G, et al. 2002. Ceramic and PMMA particles differentially affect osteoblast phenotype. Biomaterials 23:1855-1863.
16. Lohmann CH, Dean DD, Bonewald LF, et al. 2002. Nitric oxide and prostaglandin E2 production in response to ultra-high molecular weight polyethylene particles depends on osteoblast maturation state. J Bone Joint Surg Am 84:411-419.
17. Shida J, Trindade MCD, Goodman SB, et al. 2000. Induction of interleukin-6 release in human osteoblast-like cells exposed to titanium particles in vitro. Calcif Tissue Int 67:151-155.
18. Pioletti DP, Kottelat A. 2004. The influence of wear particles in the expression of osteoclastogenesis factors by osteoblasts. Biomaterials 25:5803-5808.
19. Pioletti DP, Takei H, Kwon SY, et al. 1999. The cytotoxic effect of titanium particles phagocytosed by osteoblasts. J Biomed Mater Res 46:399-407.
20. Pioletti DP, Leoni L, Genini D, et al. 2002. Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles. J Biomed Mater Res 61:408-420.
21. O'Conner DT, Choi MG, Kwon SY, et al. 2004. New insight into the mechanism of hip prosthesis loosening: effect of titanium debris size on osteoblast function. J Orthop Res 22:229-236.
22. Phinney DG, Kopen G, Isaacson RL, et al. 1999. Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. J Cell Biochem 72:570-585.
23. Wang D, Christensen K, Chawla K, et al. 1999. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res 14:893-903.
24. Quarles LD, Yohay DA, Lever LW, et al. 1992. Distinctive proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development. J Bone Miner Res 7:683-692.
25. Franceschi RT, Iyer BS, Cui Y. 1994. Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells. J Bone Miner Res 9:843-854.
26. Choi JY, Lee BH, Song KB, et al. 1996. Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells. J Cell Biochem 61:609-618.