Pathophysiological characteristics of dimethylnitrosamine-induced liver fibrosis in acute and chronic injury models: A possible contribution of KLF5 to fibrogenic responses

Digestive Diseases and Sciences

Volumn 53, Issue 8, 2008, Pages 2222-2232

  Ohara, Fumihiro ^a,b   Nii, Aisuke ^b   Sakiyama, Yojiro ^b   Tsuchiya, Megumi ^b   Ogawa, Shinji ^a,b  

^a PFIZER INC   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Dimethylnitrosamine; Hepatic stellate cell; Kruppel like factor 5; Liver fibrosis; Transdifferentiation

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; DIMETHYLNITROSAMINE; KRUEPPEL LIKE FACTOR 5 PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CONTROLLED STUDY; FIBROGENESIS; HISTOPATHOLOGY; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ACTINS; ACUTE DISEASE; ALANINE TRANSAMINASE; ANIMALS; CHRONIC DISEASE; COLLAGEN TYPE I; DIMETHYLNITROSAMINE; DISEASE MODELS, ANIMAL; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIVER; LIVER CIRRHOSIS; MALE; RATS; RATS, WISTAR; RNA, MESSENGER; TIME FACTORS; UP-REGULATION;

EID: 46449099523     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-0112-y     Document Type: Article

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