Early postnatal effects of prenatal exposure to glucocorticoids on testosterone metabolism and biogenic monoamines in discrete neuroendocrine regions of the rat brain

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 138, Issue 2, 2004, Pages 169-175

  Reznikov, A G ^a   Nosenko, N D ^a   Tarasenko, L V ^a  

^a VP Komissarenko Inst E   (Ukraine)

Author keywords

5 Reductase; Aromatase; Catecholamines; Glucocorticoids; Prenatal exposure; Rat; Serotonin; Sexual brain differentiation

Indexed keywords

BRAIN MONOAMINE; DEXAMETHASONE; DOPAMINE; GLUCOCORTICOID; SEROTONIN; TESTOSTERONE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS; MALE; NEUROENDOCRINE SYSTEM; NEUROTOXICITY; NONHUMAN; PERINATAL DRUG EXPOSURE; PREOPTIC AREA; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SEX DIFFERENCE; SEX DIFFERENTIATION; TESTOSTERONE METABOLISM;

EID: 4644371580     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2004.06.005     Document Type: Article

References (31)

1. M.J. Baum, J.A. Woutersen, and A.K. Slob Sex difference in whole-body androgen content in rats on fetal days 18 and 19 without evidence that androgen passes from males to females Biol. Reprod. 44 1991 747 751
2. B. Brodie, E. Costa, A. Dlabac, N. Neff, and H. Smookler Application of steady state kinetics to the estimation of synthesis rate and turnover time of tissue catecholamine J. Pharmacol. Ther. 154 1966 493 498
3. E.C. Davis, J.E. Shryne, and R.A. Gorski A revised critical period for the sexual differentiation of the sexually dimorphic nucleus of the preoptic area in the rat Neuroendocrinology 62 1995 579 585
4. E.R. De Kloet, E. Vreugdenhil, M.S. Oitzl, and M. Joels Brain corticosteroid receptor balance in health and disease Endocr. Rev. 19 1998 269 301
5. G. Dörner Hormones and Brain Differentiation 1976 Elsevier Amsterdam 272 pp.
6. G. Dörner Hormone-dependent brain development and neuroendocrine prophylaxis Exp. Clin. Endocrinol. 94 1989 4 22
7. N.N. Dygalo, Ò.S. Kalinina, and E.V. Naumenko Brain catecholamine system in rat fetuses under disturbed glucocorticoid balance Bull. Exp. Biol. Med. 112 1991 353 355 Rus.
8. F. Götz, and G. Dörner Homosexual behavior in prenatally stressed male rats after castration and oestrogen treatment in adulthood Endokrinologie 76 1980 115 117
9. R.R. Holson, B. Gough, P. Sullivan, T. Badger, and D.M. Sheehan Prenatal dexamethasone or stress but not ACTH or corticosterone alter sexual behavior in male rats Neurotoxicol. Teratol. 17 1995 393 401
10. D. Jacobowitz, and J. Richardson Method for the rapid determination of norepinephrine, dopamine and serotonin in the same brain region Pharmacol. Biochem. Behav. 8 1978 515 519
11. A.M. Krstulovic, and C. Matzura Rapid analysis of tryptophan metabolites using reversed-phase high-performance liquid chromatography with fluorometric detection J. Chromatogr. 163 1972 72 76
12. N.S. Levitt, R.S. Lindsay, M.C. Holmes, and J.R. Seckl Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat Neuroendocrinology 64 1996 412 418
13. L. Liu, A. Li, and S.G. Matthews Maternal glucocorticoid treatment programs HPA regulation in adult offspring: sex-specific effects Am. J. Physiol. 280 2001 E729 E739
14. N.J. MacLusky, and F. Naftolin Sexual differentiation of the central nervous system Science 211 1981 1294 1303
15. N.D. MacLusky, A. Philip, C. Hulburt, and F. Naftolin Estrogen formation in the developing rat brain: sex differences in aromatase activity during early postnatal life Psychoneuroendocrinology 77 1985 355 361
16. S.G. Matthews Antenatal glucocorticoids and programming of the developing CNS Pediatr. Res. 47 2000 291 300
17. S.G. Matthews Antenatal glucocorticoids and programming of the developing brain: mechanism of action Semin. Neonatol. 6 2001 309 317
18. K. Muneoka, M. Mikuni, T. Ogawa, K. Kitera, K. Kamei, M. Takigawa, and K. Takahashi Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring Am. J. Physiol. 273 1997 R1669 R1675
19. E.V. Naumenko, and N.N. Dygalo Role of maternal corticosteroid and epinephrine changes during pregnancy in alteration of pituitary†"adrenal reactivity of adult offspring E. Usdin R. Kavet-nansky J. Axelrod Stress: The Role of Catecholamines and Other Neurotransmitters 1984 Gordon and Breach Sci. Publ. New York 839 847
20. NIH Consensus Development Conference Effect of corticosteroids for fetal maturation and perinatal outcomes Am. J. Obstet. Gynecol. 173 1995 253 344
21. A.G. Reznikov Hormone-Transmitter Imprinting in the Neuroendocrine Control of Reproduction vol. 7, part 4 1994 Harwood Academic Publishers New York 50 pp.
22. A.G. Reznikov, and N.D. Nosenko It is possible that noradrenaline is the biogenic monoamine responsible for androgen-dependent sexual brain differentiation Exp. Clin. Endocrinol. 81 1983 91 93
23. A.G. Reznikov, and N.D. Nosenko Prevention of anovulatory syndrome and testosterone-induced rise in catecholamine level in the hypothalamus of newborn rats with steroid aromatase inhibitors Exp. Clin. Endocrinol. 90 1987 185 189
24. A.G. Reznikov, and N.D. Nosenko Some considerations on interrelation between catecholestrogens and catecholamines in androgen-dependent differentiation of the hypothalamus Neuroendocrinology: Quid novi? Brain Res. 1990 97 103 Promot., Tubingen
25. A.G. Reznikov, and N.D. Nosenko Catecholamines in steroid-dependent brain development J. Steroid Biochem. Mol. Biol. 53 1995 349 353
26. A.G. Reznikov, and N.D. Nosenko Early postnatal changes in sexual dimorphism of catecholamine and indoleamine content in the brain of prenatally stressed rats Neuroscience 70 1996 543 551
27. A.G. Reznikov, N.D. Nosenko, and L.V. Tarasenko Prenatal stress and glucocorticoid effects on the developing gender-related brain J. Steroid Biochem. Mol. Biol. 69 1999 109 115
28. A.G. Reznikov, N.D. Nosenko, and L.V. Tarasenko Hormonal participants of neurochemical feminization of developing brain preoptic area in prenatally stressed male rats Pediatr. Res. 53 2003 38
29. T.A. Slotkin, S.E. Lappi, E.C. McCook, M.I. Tayyeb, J.P. Eylers, and F.J. Seidler Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity Biol. Neonate 61 1992 326 336
30. I. Ward Prenatal stress feminizes and demasculinizes the behavior of males Science 175 1972 82 84
31. J. Weisz, and I.L. Ward Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses, and neonatal offspring Endocrinology 106 1980 306 316