Identification of a gene required for the formation of lyso-ornithine lipid, an intermediate in the biosynthesis of ornithine-containing lipids

Molecular Microbiology

Volumn 53, Issue 6, 2004, Pages 1757-1770

  Gao, Jun Lian ^a   Weissenmayer, Barbara ^a,d   Taylor, Adrian M ^b,c   Thomas Oates, Jane ^b,c   López Lara, Isabel M ^a   Geiger, Otto ^a  

^a INSTITUTO DE CIENCIAS FÍSICAS   (Mexico)

^b UNIVERSITY OF YORK   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL ACYL CARRIER PROTEIN; ACYLTRANSFERASE; CARRIER PROTEIN; FATTY ACID; LIPID; LYSOORNITHINE; ORNITHINE DERIVATIVE; PHOSPHATE; PHOSPHORUS; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BIOSYNTHESIS; ENZYME ACTIVITY; ESCHERICHIA COLI; EUBACTERIUM; GENE IDENTIFICATION; GENETIC CODE; IN VIVO STUDY; ISOTOPE LABELING; LIPID MEMBRANE; LIPOGENESIS; NONHUMAN; OLSA GENE; OLSB GENE; OPEN READING FRAME; OPERON; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHIZOBIUM; SINORHIZOBIUM MELILOTI;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; LIPIDS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTATION; OPEN READING FRAMES; ORNITHINE; SEQUENCE ALIGNMENT; SINORHIZOBIUM MELILOTI;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; RHIZOBIUM; SINORHIZOBIUM; SINORHIZOBIUM MELILOTI;

EID: 4644364774     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04240.x     Document Type: Article

References (51)

1. Allison, H.E., and Hillman, J.D. (1997) Cloning and characterization of Prevotella melaninogenica hemolysin. Infect Immun 65: 2765-2771.
2. Altschul, S.F., Madden, T.L., Schäffer, A.A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D.J. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
3. Benning, C., Huang, Z.-H., and Gage, D.A. (1995) Accumulation of a novel glycolipid and a betaine lipid in cells of Rhodobacter sphaeroides grown under phosphate limitation. Arch Biochem Biophys 317: 103-111.
4. Beringer, J.E. (1974) R factor transfer in Rhizobium leguminosarum. J Gen Microbiol 84: 188-198.
5. Bligh, E.G., and Dyer, J.W. (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
6. Boulter, D., Jeremy, J.J., and Wilding, M. (1966) Amino acids liberated into the culture medium by pea seedling roots. Plant Soil 14: 121-127.
7. Charles, T.C., Newcomb, W., and Finan, T.M. (1991) ndvF, a novel locus located on megaplasmid pRmeSU47b (pEXO) of Rhizobium meliloti, is required for normal nodule development. J Bacteriol 173: 3981-3992.
8. Dees, C., and Shively, J.M. (1982) Localization and quantitation of the ornithine lipid of Thiobacillus thiooxidans. J Bacteriol 149: 798-799.
9. Ditta, G., Schmidhauser, T., Yacobson, E., Lu, P., Liang, X.-W., Finlay, D.R., et al. (1985) Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring expression. Plasmid 13: 149-153.
10. Dulley, J.R., and Grieve, P.A. (1975) A simple technique for eliminating interference by detergents in the Lowry method of protein determination. Anal Biochem 64: 136-141.
11. Figurski, D.H., and Helinski, D.R. (1979) Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci USA 76: 1648-1652.
12. Geer, L.Y., Domrachev, M., Lipman, D.J., and Bryant, S.H. (2002) CDART: protein homology by domain architecture. Genome Res 12: 1619-1623.
13. Geiger, O., Röhrs, V., Weissenmayer, B., Finan, T.M., and Thomas-Oates, J.E. (1999) The regulator gene phoB mediates phosphate stress-controlled synthesis of the membrane lipid diacylglycerol-N,N,N- trimethylhomoserine in Rhizobium (Sinorhizobium) meliloti. Mol Microbiol 32: 63-73.
14. Gough, J., Karplus, K., Hughey, R., and Chothia, C. (2001) Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. J Mol Biol 313: 903-919.
15. Hanahan, D. (1983) Studies on transformation of Escherichia coli with plasmids. J Mol Biol 166: 557-580.
16. Heath, R.J., and Rock, C.O. (1998) A conserved histidine is essential for glycerolipid acyltransferase catalysis. J Bacteriol 180: 1425-1430.
17. Heeb, S., and Haas, D. (2001) Regulatory roles of the GacS/GacA two-component system in plant-associated and other Gram-negative bacteria. Mol Plant Microbe Interact 14: 1351-1363.
18. Kato, H., and Goto, N. (1997) Adjuvanticity of an ornithine-containing lipid of Flavobacterium meningosepticum as a candidate vaccine adjuvant. Microbiol Immunol 41: 101-106.
19. Kawai, Y., Kaneda, K., Morisawa, Y., and Akagawa, K. (1991) Protection of mice from lethal endotoxemia by use of an ornithine-containing lipid or a serine-containing lipid. Infect Immun 59: 2560-2566.
20. Kawai, Y., Nakagawa, Y., Matuyama, T., Akagawa, K., Itagawa, K., Fukase, K., et al. (1999) A typical bacterial ornithine-containing lipid N-(D)-3-(hexdecanoyloxy) hexadecanoyl-ornithine is a strong stimulant for macrophages and a useful adjuvant. FEMS Immunol Med Microbiol 23: 67-73.
21. Kawai, Y., Takasuka, N., Inoue, K., Akagawa, K., and Nishijima, M. (2000) Ornithine-containing lipids stimulate CD14-dependent TNF-a production from murine macrophage-like J774.1 and RAW 264.7 cells. FEMS Immunol Med Microbiol 28: 197-203.
22. Kawai, Y., Yano, I., and Kaneda, K. (1988) Various kinds of lipoamino acids including a novel serine-containing lipid in an opportunistic pathogen Flavobacterium. Eur J Biochem 171: 73-80.
23. Knoche, H.W., and Shively, J.M. (1972) The structure of an ornithine-containing lipid from Thiobacillus thiooxydans. J Biol Chem 247: 170-178.
24. Kretzschmar, U., Schobert, M., and Gorisch, H. (2001) The Pseudomonas aeruginosa acsA gene, encoding an acetyl-CoA synthetase, is essential for growth on ethanol. Microbiology 147: 2671-2677.
25. López-Lara, I.M., Sohlenkamp, C., and Geiger, O. (2003) Membrane lipids in plant-associated bacteria: their biosyntheses and possible functions. Mol Plant Microbe Interact 16: 567-579.
26. Meade, H.M., Long, S.R., Ruvkun, G.B., Brown, S.E., and Ausubel, F.M. (1982) Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis. J Bacteriol 149: 114-122.
27. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
28. Minnikin, D.E., and Abdolrahimzadeh, H. (1974) The replacement of phosphatidylethanolamine and acidic phospholipids by an ornithine-amide lipid and a minor phosphorous-free lipid in Pseudomonas fluorescens NCMB 129. FEBS Lett 43: 257-260.
29. Minnikin, D.E., Abdolrahimzadeh, H., and Baddiley, J. (1972) Variation of polar lipid composition of Bacillus subtilis Marburg with different growth conditions. FEBS Lett 27: 16-18.
30. Minnikin, D.E., Abdolrahimzadeh, H., and Baddiley, J. (1974) Replacement of acidic phospholipids by acidic glycolipids in Pseudomonas diminuta. Nature (London) 249: 268-269.
31. Østerås, M., Boncompagni, E., Vincent, N., Poggi, M.C., and Le Rudulier, D. (1998) Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine. Proc Natl Acad Sci USA 95: 11394-11399.
32. Pernestig, A.-K., Melefors, Ö., and Georgellis, D. (2001) Identification of UvrY as the cognate response regulator for the BarA sensor kinase in Escherichia coli. J Biol Chem 276: 225-231.
33. Phung, L.V., Chi, T.T.B., Hotta, H., Yabuchi, E., and Yano, I. (1995) Cellular lipid and fatty acid compositions of Burkholderia pseudomallei strains isolated from human and environment in Viet Nam. Microbiol Immunol 39: 105-116.
34. Raetz, C.R.H., and Whitfield, C. (2002) Lipopolysaccharide endotoxins. Annu Rev Biochem 71: 635-700.
35. de Rudder, K.E.E., Thomas-Oates, J.E., and Geiger, O. (1997) Rhizobium meliloti mutants deficient in phospholipid N-methyltransferase still contain phosphatidylcholine. J Bacterial 179: 6921-6928.
36. Ruvkun, G.B., and Ausubel, F.M. (1981) A general method for site-directed mutagenesis in procaryotes. Nature (London) 289: 85-88.
37. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
38. Sanger, F., Nickler, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
39. Sherwood, M.T. (1970) Improved synthetic medium for the growth of Rhizobium. J Appl Bacteriol 33: 708-713.
40. Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M., and Geiger, O. (2000) Cloning and characterization of the gene for phosphatidylcholine synthase. J Biol Chem 275: 18919-18925.
41. Soto, M.J., van Dillewijn, P., Olivares, J., and Toro, N. (1994) Ornithine cyclodeaminase activity in Rhizobium meliloti. FEMS Microbiol Lett 119: 209-214.
42. Spaink, H.P., Wijfjes, A.H.M., and Lugtenberg, B.J.J. (1995) Rhizobium Nodl and NodJ proteins play a role in the efficiency of secretion of lipochitin oligosaccharides. J Bacteriol 177: 6276-6281.
43. Staskawicz, B., Dahlbeck, D., Keen, N., and Napoli, C. (1987) Molecular characterization of cloned avirulence genes from race 0 and race 1 of Pseudomonas syringae pv. Glycinea. J Bacteriol 169: 5789-5794.
44. Studier, F.W., Rosenberg, A.H., Dunn, J.J., and Dubendorff, J.W. (1990) Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol 185: 60-89.
45. Tatusov, R.L., Natale, D.A., Garkavtsev, I.V., Tatusova, T.A., Shankavaram, U.T., Rao, B.S., et al. (2001) The COG database: new developments in phylogenetic classification of proteins from complete genomes. Nucleic Acids Res 29: 22-28.
46. Thiehle, O.W., and Schwinn, G. (1973) The free lipids of Brucella melitensis and Bordetella pertussis. Eur J Biochem 34: 333-344.
47. Thompson, J.D., Higgins, D.G., and Gibson, T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
48. Trovato, M., Maras, B., Linhares, F., and Costantino, P. (2001) The plant oncogene rolD encodes a functional ornithine cyclodeaminase. Proc Natl Acad Sci USA 98: 13449-13453.
49. Voegele, R.T., Mitsch, M.J., and Finan, T.M. (1999) Characterization of two members of a novel malic enzyme class. Biochim Biophys Acta 1432: 275-285.
50. Weissenmayer, B., Gao, J.-L., López-Lara, I.M., and Geiger, O. (2002) Identification of a gene required for the biosynthesis of ornithine-derived lipids. Mol Microbiol 45: 721-733.
51. Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33: 103-119.