Death receptor 3 (DR3) gene duplication in a chromosome region 1p36.3: Gene duplication is more prevalent in rheumatoid arthritis

Genes and Immunity

Volumn 5, Issue 6, 2004, Pages 439-443

  Osawa, K ^a,b   Takami, N ^a,b   Shiozawa, K ^c   Hashiramoto, A ^a,b,d   Shiozawa, S ^a,b,d,e  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Konan Kakogawa Hospital   (Japan)

^d KOBE UNIVERSITY HOSPITAL   (Japan)

^e Investigator of Center of Excellence   (Japan)

Author keywords

Death receptor 3 (DR3); Fluorescence in situ hybridization (FISH); Gene duplication; Rheumatoid arthritis (RA)

Indexed keywords

DEATH RECEPTOR 3; FAS LIGAND; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ARTIFICIAL CHROMOSOME; CHROMOSOME 1P; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DUPLICATION; GENE MUTATION; GENE SEQUENCE; HUMAN; MALE; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 1; GENE DUPLICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; PREVALENCE; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 25; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 4644359892     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6364097     Document Type: Article

References (19)

1. Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001; 104: 487-501.
2. Kitson J, Raven T, Jiang YP et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996; 384: 372-375.
3. Chinnaiyan AM, O'Rourke K, Yu GL et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274: 990-992.
4. Marsters SA, Sheridan JP, Donahue CJ et al. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB. Curr Biol 1996; 6: 1669-1676.
5. Shiozawa S, Hayashi S, Tsukamoto Y et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998; 10: 1891-1895.
6. Shiozawa S, Hashiramoto A, Kawasaki H et al. Evidence for functional variation of the death receptor 3 (DR3) gene that inhibits apoptosis and predisposes to progressive joint destruction in 'rheumatoid arthritis. submitted for publication.
7. Grenet J, Valentine V, Kitson J, Li H, Farrow SN, Kidd VJ. Duplication of the DR3 gene on human chromosome 1p36 and its deletion in human neuroblastoma. Genomics 1998; 49: 385-393.
8. Gururajan R, Lahti JM, Grenet J et al. Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2. Genome Res 1998; 8: 929-939.
9. Suto Y, Ishikawa Y, Hyodo H, Uchikawa M, Juji T. Gene organization and rearrangements at the human Rhesus blood group locus revealed by fiber-FISH analysis. Hum Genet 2000; 106: 164-171.
10. Kemper O, Derré J, Cherif D, Engelmann H, Wallach D, Berger R. The gene for the type II (p75) tumor necrosis factor receptor (TNF-RII) is localized on band 1p36.2-p36.3. Hum Genet 1991; 87: 623-624.
11. Fonatsch C, Latza U, Dürkop H, Rieder H, Stein H. Assignment of the human CD30 (Ki-1) gene to 1p36. Genomics 1992; 14: 825-826.
12. Latza U, Dürkop H, Schnittger S et al. The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen. Eur J Immunol 1994; 24: 677-683.
13. Schwarz H, Arden K, Lotz M. CD137, a member of the tumor necrosis factor receptor family, is located on chromosome 1p36, in a cluster of related genes, and colocalizes with several malignancies. Biochem Biophys Res Commun 1997; 235: 699-703.
14. Ohno S. Evolution by Gene Duplication. Springer-Verlag: Berlin, 1970.
15. Lynch M, Conery JS. The evolutionary fate and consequences of duplicate genes. Science 2000; 290: 1151-1155.
16. Parra I, Windle B. High resolution visual mapping of stretched DNA by fluorescent hybridization. Nat Genet 1993; 5: 17-21.
17. Fidlerová H, Senger G, Kost M, Sanseau P, Sheer D. Two simple procedures for releasing chromatin from routinely fixed cells for fluorescence in situ hybridization. Cytogenet Cell Genet 1994; 65: 203-205.
18. Germer S, Holland MJ, Higuchi R. High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res 2000; 10: 258-266.
19. Arnett FC, Edworthy SM, Bloch DA et al. The American rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-324.