Purification of recombinant adeno-associated virus type 8 vectors by ion exchange chromatography generates clinical grade vector stock

Journal of Virological Methods

Volumn 121, Issue 2, 2004, Pages 209-215

  Davidoff, Andrew M ^a   Ng, Catherine Y C ^a   Sleep, Susan ^a   Gray, John ^a   Azam, Selina ^b   Zhao, Yuan ^b   McIntosh, Jenny H ^c   Karimipoor, Morteza ^c   Nathwani, Amit C ^c,d  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

Ion exchange chromatography; rAAV 8 purification

Indexed keywords

ADENOVIRUS VECTOR; BLOOD CLOTTING FACTOR 9;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYO; GENETIC CODE; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; ION EXCHANGE CHROMATOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; VIRAL GENE DELIVERY SYSTEM; VIRION; VIRUS PARTICLE; VIRUS PURIFICATION; VIRUS RECOMBINANT;

ANIMALS; CHROMATOGRAPHY, ION EXCHANGE; DEPENDOVIRUS; FACTOR IX; GENETIC VECTORS; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED C57BL; RECOMBINATION, GENETIC;

ADENO-ASSOCIATED VIRUS;

EID: 4644321610     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2004.07.001     Document Type: Article

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