Overrepresentation of 8q in carcinosarcomas and endometrial adenocarcinomas

American Journal of Clinical Pathology

Volumn 122, Issue 4, 2004, Pages 546-551

  Schulten, Hans Jürgen ^a   Gunawan, Bastian ^a   Enders, Christina ^a   Donhuijsen, Konrad ^b   Emons, Günter ^a   Füzesi, László ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b City Hospital   (Germany)

Author keywords

8q; Carcinosarcoma; Comparative genomic hybridization

Indexed keywords

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CARCINOSARCOMA; CHROMOSOME 8; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; ENDOMETRIUM CARCINOMA; FEMALE; HUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 4644316599     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/MBQ1ECRYU8CRD2WH     Document Type: Article

References (37)

1. McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas? J Clin Pathol. 2002;55:321-325.
2. Shen DH, Khoo US, Xue WC, et al. Primary peritoneal malignant mixed müllerian tumors: a clinicopathologic, immunohistochemical, and genetic study. Cancer. 2001;91:1052-1060.
3. Blom R, Guerrieri C, Stal O, et al. Malignant mixed müllerian tumors of the uterus: a clinicopathologic, DNA flow cytometric, p53, and mdm-2 analysis of 44 cases. Gynecol Oncol. 1998;68:18-24.
4. Iwasa Y, Haga H, Konishi I, et al. Prognostic factors in uterine carcinosarcoma: a clinicopathologic study of 25 patients. Cancer. 1998;82:512-519.
5. Inthasom P, Carter J, Valmadre S, et al. Analysis of clinicopathologic factors in malignant mixed müllerian tumors of the uterine corpus. Int J Gynecol Cancer. 2002;12:348-353.
6. Abeln EC, Smit VT, Wessels JW, et al. Molecular genetic evidence for the conversion hypothesis of the origin of malignant mixed müllerian tumours. J Pathol. 1997;183:424-431.
7. Thompson L, Chang B, Barsky SH. Monoclonal origins of malignant mixed tumors (carcinosarcomas); evidence for a divergent histogenesis. Am J Surg Pathol. 1996;20:277-285.
8. Wada H, Enomoto T, Fujita M, et al. Molecular evidence that most but not all carcinosarcomas of the uterus are combination tumors. Cancer Res. 1997;57:5379-5385.
9. Kounelis S, Jones MW, Papadaki H, et al. Carcinosarcomas (malignant mixed müllerian tumors) of the female genital tract: comparative molecular analysis of epithelial and mesenchymal components. Hum Pathol. 1998;29:82-87.
10. Emoto M, Iwasaki H, Kikuchi M, et al. Two cell lines established from mixed müllerian tumors of the uterus: morphologic, immunocytochemical, and cytogenetic analyses. Cancer. 1992;69:1759-1768.
11. Kitagawa K, Murata A, Matsuura N, et al. Epithelial-mesenchymal transformation of a newly established cell line from ovarian adenosarcoma by transforming growth factor-beta1. Int J Cancer. 1996;66:91-97.
12. Mayall F, Rutty K, Campbell F, et al. p53 immunostaining suggests that uterine carcinosarcomas are monoclonal. Histopathology. 1994;24:211-214.
13. Guarino M, Giordano F, Pallotti F, et al. Malignant mixed müllerian tumor of the uterus: features favoring its origin from a common cell clone and an epithelial-to-mesenchymal transformation mechanism of histogenesis. Tumori. 1998;84:391-397.
14. Scully RE, Bonfiglio TA, Kurman RJ, et al. Histological Typing of Female Genital Tract Tumours. Berlin, Germany: Springer-Verlag; 1994.
15. Nagel H, Schulten HJ, Gunawan B, et al. The potential value of comparative genomic hybridization analysis in effusion- and fine needle aspiration cytology. Mod Pathol. 2002;15:818-825.
16. Wilkens L, Tchinda J, Burkhardt D, et al. Significant hybridization differences in comparative genomic hybridization due to nucleotides used for DNA labelling and to DNA chosen for cohybridization. Pathobiology. 2002-2003;70:204-208.
17. Solinas-Toldo S, Wallrapp C, Muller-Pillasch F, et al. Mapping of chromosomal imbalances in pancreatic carcinoma by comparative genomic hybridization. Cancer Res. 1996;56:3803-3807.
18. Milatovich A, Heerema NA, Palmer CG. Cytogenetic studies of endometrial malignancies. Cancer Genet Cytogenet. 1990;46:41-53.
19. Tibiletti MG, Bernasconi B, Taborelli M, et al. Involvement of chromosome 6 in endometrial cancer. Br J Cancer. 1997;75:1831-1835.
20. Sreekantaiah C, Kwark E, Chuang LT, et al. Cytogenetic and molecular characterization of a malignant mixed müllerian tumor of the uterus with a t(8;22)(q24.1;q12). Cancer Genet Cytogenet. 1999;115:73-76.
21. Gil-Benso R, Lopez-Gines C, Carda-Batalla C, et al. Cytogenetic findings in malignant mixed mesodermal tumors of the uterus. Cancer Genet Cytogenet. 1997;99:121-125.
22. Sreekantaiah C, Rao UN, Sandberg AA. Complex karyotypic aberrations, including i(12p), in malignant mixed müllerian tumor of uterus. Cancer Genet Cytogenet. 1992;60:78-81.
23. Gunawan B, Baumhoer D, Schulten HJ, et al. Polysomy 8 in three cases of homologous malignant mixed müllerian tumors of the uterus. Anticancer Res. 2003;23:1379-1384.
24. Emoto M, Iwasaki H, Oshima K, et al. Characteristics of rhabdomyosarcoma cell lines derived from uterine carcinosarcomas. Virchows Arch. 1997;431:249-256.
25. Nilbert M, Jin YS, Heim S, et al. Chromosome rearrangements in two uterine sarcomas. Cancer Genet Cytogenet. 1990;44:27-35.
26. Laxman R, Currie JL, Kurman RJ, et al. Cytogenetic profile of uterine sarcomas. Cancer. 1993;71:1283-1288.
27. Iliszko M, Mandahl N, Mrozek K, et al. Cytogenetics of uterine sarcomas: presentation of eight new cases and review of the literature. Gynecol Oncol. 1998;71:172-176.
28. Micci F, Walter CU, Teixeira MR, et al. Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17). Cancer Genet Cytogenet. 2003;144:119-124.
29. Huang HY, Ladanyi M, Soslow RA. Molecular detection of JAZF1-JJAZ1 gene fusion in endometrial stromal neoplasms with classic and variant histology: evidence for genetic heterogeneity. Am J Surg Pathol. 2004;28:224-232.
30. Suehiro Y, Umayahara K, Ogata H, et al. Genetic aberrations detected by comparative genomic hybridization predict outcome in patients with endometrioid carcinoma. Genes Chromosomes Cancer. 2000;29:75-82.
31. Nesbit CE, Tersak JM, Prochownik EV. myc oncogenes and human neoplastic disease. Oncogene. 1999;18:3004-3016.
32. Jeffers MD, Richmond JA, Macaulay EM. Overexpression of the c-myc proto-oncogene occurs frequently in uterine sarcomas. Mod Pathol. 1995;8:701-704.
33. McCluggage WG. Uterine carcinosarcomas (malignant mixed müllerian tumors) are metaplastic carcinomas. Int J Gynecol Cancer. 2002;12:687-690.
34. Seidman JD, Chauhan S. Evaluation of the relationship between adenosarcoma and carcinosarcoma and a hypothesis of the histogenesis of uterine sarcomas. Int J Gynecol Pathol. 2003;22:75-82.
35. Kiechle M, Hinrichs M, Jacobsen A, et al. Genetic imbalances in precursor lesions of endometrial cancer detected by comparative genomic hybridization. Am J Pathol. 2000;156:1827-1833.
36. Sonoda G, du Manoir S, Godwin AK, et al. Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization. Genes Chromosomes Cancer. 1997;18:115-125.
37. Suzuki A, Fukushige S, Nagase S, et al. Frequent gains on chromosome arms 1q and/or 8q in human endometrial cancer. Hum Genet. 1997;100:629-636.