Phytosterolemia on the island of Kosrae: Founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels

Journal of Lipid Research

Volumn 45, Issue 9, 2004, Pages 1608-1613

  Sehayek, Ephraim ^a   Yu, Hannah J ^a   Von Bergmann, Klaus ^b   Lutjohann, Dieter ^b   Stoffel, Markus ^a   Duncan, Elizabeth M ^a   Garcia Naveda, Laura ^a   Salit, Jacqueline ^a   Blundell, Maude L ^a   Friedman, Jeffrey M ^a   Breslow, Jan L ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

ATP binding cassette subfamily G member 8; Cholesterol absorption; Population genetics

Indexed keywords

ABC TRANSPORTER; ABCG8 PROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CAMPESTEROL; GLUTAMINE; HISTIDINE; LATHOSTEROL; PHYTOSTEROL; SITOSTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ABCG8 GENE; ADULT; AGED; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL SYNTHESIS; CODON; DNA SEQUENCE; EXON; FEMALE; FOUNDER EFFECT; FRAMESHIFT MUTATION; GENE; GENE MUTATION; HETEROZYGOTE; HUMAN; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PLANT; PRIORITY JOURNAL; SCREENING; SITOSTEROLEMIA; STOP CODON;

ADULT; AGED; AGED, 80 AND OVER; ATP-BINDING CASSETTE TRANSPORTERS; DIET; FEMALE; FOUNDER EFFECT; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERLIPIDEMIAS; LIPOPROTEINS; MALE; MICRONESIA; MIDDLE AGED; MUTATION; PHYLOGENY; PHYTOSTEROLS;

EID: 4644309549     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M400006-JLR200     Document Type: Article

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