Effect of cyclo-oxygenase inhibitors on Helicobacter pylori susceptibility to metronidazole and clarithromycin

Alimentary Pharmacology and Therapeutics

Volumn 20, Issue 6, 2004, Pages 675-681

  Gu, Q ^a   Xia, H H X ^a   Wang, W H ^a,b   Wang, J D ^a   Wong, W M ^a   Chan, A O O ^a   Yuen, M F ^a   Lam, S K ^a   Cheung, H K L ^a   Liu, X G ^b   Wong, B C Y ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; CLARITHROMYCIN; INDOMETACIN; METRONIDAZOLE; PROSTAGLANDIN SYNTHASE INHIBITOR; UREASE;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; BRUCELLA; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GROWTH INHIBITION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; CELLS, CULTURED; CLARITHROMYCIN; CYCLOOXYGENASE INHIBITORS; DRUG INTERACTIONS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; METRONIDAZOLE; PYRAZOLES; SULFONAMIDES;

EID: 4644309194     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2004.02168.x     Document Type: Article

References (28)

1. Romano M, Ricci V, Memoli A, et al. Helicobacter pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN28 gastric mucosal cells in vitro. J Biol Chem 1998; 273: 28560-3.
2. Kim JM, Kim JS, Jung HC, et al. Upregulated cyclooxygenase-2 inhibits apoptosis of human gastric epithelial cells infected with Helicobacter pylori. Dig Dis Sci 2000; 45: 2436-43.
3. Bhang CS, Lee HS, Kim SS, et al. Effects of selective cyclooxygenase-2 inhibitor and non-selective NSAIDs on Helicobacter pylori-induced gastritis in Mongolian gerbils. Helicobacter 2002; 7: 14-21.
4. Cryer B, Feldman M. Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. Gastroenterology 1999; 117: 17-25.
5. Takahashi S, Fujita T, Yamamoto A. Role of cyclooxygenase-2 in Helicobacter pylori- induced gastritis in Mongolian gerbils. Am J Physiol Gastrointest Liver Physiol 2000; 279: G791-8.
6. Yoshida N, Sugimoto N, Hirayama F, et al. Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils. Gut 2002; 50: 594-8.
7. Lai KC, Lam SK, Chu KM, et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med 2002; 346: 2033-8.
8. Pawlik T, Konturek PC, Konturek JW, et al. Impact of Helicobacter pylori and nonsteroidal anti-inflammatory drugs on gastric ulcerogenesis in experimental animals and in humans. Eur J Pharmacol 2002; 449: 1-15.
9. Konturek PC, Konturek SJ, Czesnikiewicz M, et al. Interaction of Helicobacter pylori (Hp) and nonsteroidal anti-inflammatory drugs (NSAID) on gastric mucosa and risk of ulcerations. Med Sci Monit 2002; 8: RA197-209.
10. Kemppainen H, Raiha I, Kujari H, et al. Characteristics of Helicobacter pylori-negative and -positive peptic ulcer disease. Age Ageing 1998; 27: 427-31.
11. Nensey YM, Schubert TT, Bologna SD, et al. Helicobacter pylori-negative duodenal ulcer. Am J Med 1991; 91: 15-8.
12. Borody TJ, George LL, Brandi S, et al. Helicobacter pylori-negative duodenal ulcer. Am J Gastroenterol 1991; 86: 1154-7.
13. Xia HHX, Wong BCY, Wong KW et al Clinical and endoscopic characteristics of non -Helicobacter pylori, non-NSAID duodenal ulcers: a long-term prospective study. Aliment Pharmacol Ther 2001; 15: 1875-82.
14. Wang WH, Wong WM, Dailidiene D, et al. Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents. Gut 2003; 52: 490-195.
15. Ng FH, Wong SY, Kng C, et al. Effect of simethicone on the accuracy of the rapid urease test. Eur J Gastroenterol Hepatol 1998; 10: 851-4.
16. Xia HX, Keane CT, Beattie S, O'Morain CA. Standardization of disc diffusion test and its clinical significance for susceptibility testing of metronidazole against Helicobacter pylori. Antimicrob Agents Chemother 1994; 38: 2357-61.
17. Cryer B. The role of cyclooxygenase selective inhibitors in the gastrointestinal tract. Curr Gastroenterol Rep 2003; 5: 453-8.
18. Colville-Nash PR, Gilroy DW. Cyclooxygenase enzymes as targets for therapeutic intervention in inflammation. Drug News Perspect 2000; 13: 587-97.
19. Hu PJ, Yu J, Zeng ZR, et al. Chemoprevention of gastric cancer by celecoxib in rats. Gut 2004; 53: 195-200.
20. Wong BC, Jiang X, Fan XM, et al Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer. Oncogene 2003; 22: 1189-97.
21. Wong BC, Lam SK, Wong WM, et al. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA 2004; 291: 187-94.
22. Varro A, Noble PJ, Pritchard DM, et al. Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis. Cancer Res 2004; 64: 1695-702.
23. Akhtar M, Cheng Y, Magno RM, et al. Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. Cancer Res 2001; 61: 2399-403.
24. Wong BCY, Jiang XH, Lin MCM et al. Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase. Gastroenterology 2004; 126: 136-47.
25. Wong BCY, Jiang XH, Fan XM, et al. Suppression of RelA/p65 nuclear translocation independent of IkB-a degradation by cyclooxygenase-2 inhibitor in gastric cancer. Oncogene 2003; 22: 1189-97.
26. 1- dependent pathway. Oncogene 2002; 21: 6113-22.
27. Alekshun MN, Levy SB. Regulation of chromosomally meditated multiple antibiotic resistance: the mar regulon. Antimicrob Agents Chemother 1997; 41: 2067-75.
28. Cohen SP, Levy SB, Foulds J, Rosner JL. Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway. J Bacteriol 1993; 175: 7856-62.