Effect of edaravone on streptomycin-induced vestibulotoxicity in the guinea pig

Laryngoscope

Volumn 114, Issue 9 I, 2004, Pages 1630-1632

  Horiike, Osamu ^a   Shimogori, Hiroaki ^a   Yamashita, Hiroshi ^a,b  

^a YAMAGUCHI UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Edaravone; Guinea pig; Osmotic pump; Spontaneous nystagmus; Streptomycin; Topical administration

Indexed keywords

GELFOAM; NORPHENAZONE; STREPTOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GUINEA PIG; HEAD TILTING; MALE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; VESTIBULAR DISORDER; VESTIBULAR NYSTAGMUS; VESTIBULAR TOXICITY; YAWS;

ADMINISTRATION, TOPICAL; ANIMALS; ANTIPYRINE; EAR, INNER; ELECTRONYSTAGMOGRAPHY; FREE RADICAL SCAVENGERS; GUINEA PIGS; INJECTIONS, INTRAPERITONEAL; MALE; MUSCULOSKELETAL EQUILIBRIUM; STREPTOMYCIN; VESTIBULE;

EID: 4644307514     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005537-200409000-00023     Document Type: Article

References (18)

1. Horiike O, Shimogori H, Ikeda T, Yamashita H. Protective effect of edaravone against streptomycin-induced vestibulotoxicity in the guinea pig. Eur J Pharmacol 2003;464:75-78.
2. Nakagawa T, Yamane H, Takayama M, Sunami K, Nakai Y. Involvement of nitric oxide in aminoglycoside vestibulotoxicity in the guinea pig. Neurosci Lett 1999;267:57-60.
3. Sha SH, Schacht J. Antioxidants attenuate gentamicin-induced free radical formation in vitro and ototoxicity in vivo: D-methionine is a potential protectant. Hear Res 2000;142:34-40.
4. Sinswat P, Wu WJ, Sha SH, Schacht J. Protection from ototoxicity of intraperitoneal gentamicin in the guinea pig. Kidney Int 2000;58:2525-2532.
5. Song BB, Sha SH, Schacht J. Iron chelators protect from aminoglycoside-induced cochleo- and vestibulo-toxicity. Free Radical Biol Med 1998;20:189-195.
6. Takumida M, Anniko M. Brain-derived neurotrophic factor and nitric oxide synthase inhibitor protect the vestibular organ against gentamicin ototoxicity. Acta Otolaryngol 2002;122:10-15.
7. Watanabe T, Morita I, Nishi H, Murota S. Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial injury in vitro. Prostaglandins Leukot Essent Fatty Acids 1988;33:81-87.
8. Yamamoto T, Yuki S, Watanabe T, Mitsuka M, Saito KI, Kogure K. Delayed neuron death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia. Brain Res 1997;762:240-242.
9. Silverstein H. Use of a new device, the MicroWick, to deliver medication to the inner ear. Ear Nose Throat J 1999;78:595-600.
10. Curthoys IS, Smith PF, Darlington CL. Postural compensation in the guinea pig following unilateral labyrinthectomy. In: Pompeiano O, Allum JHJ, eds. Progress in Brain Research: Vestibulospinal Control of Posture and Locomotion. Amsterdam: Elsevier; 1988:375-384.
11. Sha SH, Schacht J. Stimulation of free radical formation by aminoglycoside antibiotics. Hear Res 1999;128:112-118.
12. Tabuchi K, Tsuji S, Ito Z, Hara A, Kusakari J. Does xanthine oxidase contribute to the hydroxyl radical generation in ischemia and reperfusion of the cochlea? Hear Res 2001;153:1-6.
13. de Groot H. Reactive oxygen species in tissue injury. Hepatogastroenterology 1994;41:328-332.
14. Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990;186:1-85.
15. Shimogori H, Yamashita H. Rapid correction of vestibular imbalance by intracochlear administration of ATP in a guinea pig model of unilateral peripheral vestibular disorder. Neurosci Lett 2001;315:69-72.
16. Shimogori H, Yamashita H. Efficacy of intracochlear administration of betamethasone on peripheral vestibular disorder in the guinea pig. Neurosci Lett 2000;294:21-24.
17. Shimogori H, Yamashita H, Watanabe T, Nakamura S. A role of glucocorticoid receptors in the guinea pig vestibular system. Brain Res 1999;851:258-260.
18. Sugahara K, Shimogori H, Yamashita H. The role of acidic fibroblast growth factor in recovery of acoustic trauma. Neuroreport 2001;12:3299-3302.