Synthesis and antitumor activity of bicyclo[3.3.1]nonenol derivatives

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 21, 2004, Pages 5563-5569

  Geirsson, Jon K F ^a   Jonsson, Stefan ^a   Valgeirsson, Jon ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

Author keywords

Antitumor activity; Bicyclo 3.3.1 nonane; Cinnamoyl side chains; Stereoselective synthesis

Indexed keywords

2,4,8,9 TETRAKIS(METHOXYCARBONYL) 6 METHYL 7 PHENYLBICYCLO[3.3.1]NON 3 ENE 1,3 DIOL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 6,7 DIMETHYLBICYCLO[3.3.1]NON 3 ENE 1,3 DIOL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYL 3 (2,3 DIPHENYLPROPENOYLOXY) BICYCLO[3.3.1]NON 3 EN 1 OL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYL 3 (3 PHENYLPROPENOYLOXY) BICYCLO[3.3.1]NON EN 1 OL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYL 3 [2 PHENYL 3 (2,6 DIFLUOROPHENYL)PROPENOYLOXY]BICYCLO[3.3.1]NON 3 ENOL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYL 3 [2 PHENYL 3 (4 CHLOROPHENYL)PROPENOYLOXY]BICYCLO[3.3.1]NON 3 ENOL; 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYL 3 [3 (4 CHLOROPHENYL) PROPENOYLOXY]BICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2 (2,4 DICHLOROPHENYL) 3 PHENYLPROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHOXYBICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2 (4 CHLOROPHENYL) 3 PHENYLPROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYLBICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2 (4 METHOXYPHENYL) 3 PHENYLPROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYLBICYCLO[3.3.1]NON 3 ENOL; 3 [2 (4 NITROPHENYL) 3 PHENYLPROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYLBICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2,3 BIS(2,4 DICHLOROPHENYL) 3 PHENYLPROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYLBICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2,3 BIS(4 CHLOROPHENYL)PROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 PHENYLBICYCLO[3.3.1]NON 3 EN 1 OL; 3 [2,3 BIS(4 CHLOROPHENYL)PROPENOYLOXY]2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 METHYLBICYCLO[3.3.1]NON 3 ENOL; 3 [3 (4 CHLOROPHENYL)PROPENOYLOXY] 2,4,8,9 TETRAKIS(METHOXYCARBONYL) 7 PHENYLBICYCLO[3.3.1]NON 3 ENOL; ALCOHOL DERIVATIVE; ANTINEOPLASTIC AGENT; CINNAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL LINE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BICYCLO COMPOUNDS; BRIDGED COMPOUNDS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS;

EID: 4644304931     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.08.006     Document Type: Article

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