메뉴 건너뛰기




Volumn 59, Issue 9, 2004, Pages 668-672

Synthesis of potential metabolites of (S)-(-)-bromofosfamide

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 BROMOETHYL) N (2 CHLOROETHYL)TETRAHYDRO 2H 1,3,2 OXAZAPHOSPHORIN 2 AMINE 2,4 DIOXIDE; 3 (2 BROMOETHYL)TETRAHYDRO 2H 1,3,2 OXAZAPHOSPHORIN 2 AMINE 2 OXIDE; ANTINEOPLASTIC AGENT; BROMINE DERIVATIVE; BROMOFOSFAMIDE; DRUG METABOLITE; IFOSFAMIDE; N (2 CHLOROETHYL)TETRAHYDRO 2H 1,3,2 OXAZAPHOSPHORRIN 2 AMINE 2 OXIDE; O (3 CARBOXYPROPYL) N (2 BROMOETHYL) N' (2 CHLOROETHYL)PHOSPHORODIAMIDATE; UNCLASSIFIED DRUG;

EID: 4644281439     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (21)
  • 1
    • 0031878067 scopus 로고    scopus 로고
    • The role of ifosfamide in paediatric cancer
    • Advani SH (1998) The role of ifosfamide in paediatric cancer. Aust New Zealand J Med 28: 410-413.
    • (1998) Aust New Zealand J Med , vol.28 , pp. 410-413
    • Advani, S.H.1
  • 2
    • 0032849314 scopus 로고    scopus 로고
    • HPLC separation of enantiomers of bromofosfamide and its metabolites using a chiral stationary phase
    • Bielejewska A, Sinibaldi M, Grynkiewicz G, Kutner A (1999) HPLC separation of enantiomers of bromofosfamide and its metabolites using a chiral stationary phase. Pharm Pharmacol Commun 5: 537-539.
    • (1999) Pharm Pharmacol Commun , vol.5 , pp. 537-539
    • Bielejewska, A.1    Sinibaldi, M.2    Grynkiewicz, G.3    Kutner, A.4
  • 3
    • 0034053590 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of oxazaphosphorines
    • Boddy AV, Yule SM (2000) Metabolism and pharmacokinetics of oxazaphosphorines. Clin Pharmacokinet 38: 291-304.
    • (2000) Clin Pharmacokinet , vol.38 , pp. 291-304
    • Boddy, A.V.1    Yule, S.M.2
  • 4
    • 1842299275 scopus 로고    scopus 로고
    • Enantioselective cytotoxic activity of bromine-substituted analogues of ifosfamide. A microsomal implication
    • Hladon B, Sloderbach A, Laskowska H (1997) Enantioselective cytotoxic activity of bromine-substituted analogues of ifosfamide. A microsomal implication. Pol J Pharmacol 49: 127-136.
    • (1997) Pol J Pharmacol , vol.49 , pp. 127-136
    • Hladon, B.1    Sloderbach, A.2    Laskowska, H.3
  • 7
    • 0034913438 scopus 로고    scopus 로고
    • Pharmacokinetics of (-)-(S)-bromofosfamide after intravenous and oral administration in mice
    • Kobylinska K, Kobylinska M, Sobik B (2001a) Pharmacokinetics of (-)-(S)-bromofosfamide after intravenous and oral administration in mice. Arzneim-Forsch/Drug Res 51: 596-599.
    • (2001) Arzneim-Forsch/Drug Res , vol.51 , pp. 596-599
    • Kobylinska, K.1    Kobylinska, M.2    Sobik, B.3
  • 9
    • 0019395154 scopus 로고
    • The synthesis of enantiomers of 4-ketocyclophosphamide
    • Misiura K, Pankiewicz K, Stec WJ, Jarman M (1981) The synthesis of enantiomers of 4-ketocyclophosphamide. Experientia 37: 216-217.
    • (1981) Experientia , vol.37 , pp. 216-217
    • Misiura, K.1    Pankiewicz, K.2    Stec, W.J.3    Jarman, M.4
  • 10
    • 0020580045 scopus 로고
    • Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine
    • Misiura K, Okruszek A, Pankiewicz K, Stec WJ, Czownicki Z, Utracka B (1983) Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine. J Med Chem 26: 674-679.
    • (1983) J Med Chem , vol.26 , pp. 674-679
    • Misiura, K.1    Okruszek, A.2    Pankiewicz, K.3    Stec, W.J.4    Czownicki, Z.5    Utracka, B.6
  • 11
    • 0023852330 scopus 로고
    • Synthesis and antitumor activity of analogues of ifosfamide modified in the N-(2-chloroethyl) Group
    • Misiura K, Kinas RW, Stec WJ, Kusnierczyk H, Radzikowski C, Sonoda A (1988) Synthesis and antitumor activity of analogues of ifosfamide modified in the N-(2-chloroethyl) Group. J Med Chem 31: 226-230.
    • (1988) J Med Chem , vol.31 , pp. 226-230
    • Misiura, K.1    Kinas, R.W.2    Stec, W.J.3    Kusnierczyk, H.4    Radzikowski, C.5    Sonoda, A.6
  • 12
    • 0034945173 scopus 로고    scopus 로고
    • (S)-(-)-bromofosfamide (CBM-11): Synthesis and antitumour activity and toxicity in mice
    • Misiura K, Kinas RW, Kusnierczyk H, Radzikowski C, Stec WJ (2001) (S)-(-)-bromofosfamide (CBM-11): synthesis and antitumour activity and toxicity in mice. Anti-Cancer Drugs 12: 453-458.
    • (2001) Anti-Cancer Drugs , vol.12 , pp. 453-458
    • Misiura, K.1    Kinas, R.W.2    Kusnierczyk, H.3    Radzikowski, C.4    Stec, W.J.5
  • 13
    • 0036534017 scopus 로고    scopus 로고
    • Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue
    • Misiura K, Szymanowicz D, Kusnierczyk H, Wietrzyk J, Opolski A (2002) Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue. Farmaco 57: 315-319.
    • (2002) Farmaco , vol.57 , pp. 315-319
    • Misiura, K.1    Szymanowicz, D.2    Kusnierczyk, H.3    Wietrzyk, J.4    Opolski, A.5
  • 16
    • 0032956788 scopus 로고    scopus 로고
    • The role of chemotherapy in the treatment of adult soft tissue sarcomas
    • O'Byrne K, Steward WP (1999) The role of chemotherapy in the treatment of adult soft tissue sarcomas. Oncology 56: 13-23.
    • (1999) Oncology , vol.56 , pp. 13-23
    • O'Byrne, K.1    Steward, W.P.2
  • 17
    • 0018578632 scopus 로고
    • Synthesis and absolute configuration assignments of enantiomeric forms of ifosphamide, sulfosphamide, and trofosphamide
    • Pankiewicz K, Kinas R, Stec WJ, Foster AB, Jarman M, van Maanen JMS (1979) Synthesis and absolute configuration assignments of enantiomeric forms of ifosphamide, sulfosphamide, and trofosphamide. J Am Chem Soc 101: 7712-7718.
    • (1979) J Am Chem Soc , vol.101 , pp. 7712-7718
    • Pankiewicz, K.1    Kinas, R.2    Stec, W.J.3    Foster, A.B.4    Jarman, M.5    Van Maanen, J.M.S.6
  • 18
    • 0037021096 scopus 로고    scopus 로고
    • A new method for distinguishing between enantiomers and racemates and assignment of enantiomeric purity by means of solid-state NMR. Examples from oxazaphos-phorinanes
    • Potrzebowski MJ, Tadeusiak E, Misiura K, Ciesielski W, Bujacz G, Tekely P (2002) A new method for distinguishing between enantiomers and racemates and assignment of enantiomeric purity by means of solid-state NMR. Examples from oxazaphos-phorinanes. Chem Eur J 8: 5007-5011.
    • (2002) Chem Eur J , vol.8 , pp. 5007-5011
    • Potrzebowski, M.J.1    Tadeusiak, E.2    Misiura, K.3    Ciesielski, W.4    Bujacz, G.5    Tekely, P.6
  • 21
    • 0017758224 scopus 로고
    • Studies on the urinary metabolites of isophosphamide and its activated species in rabbits
    • Takamizawa A, Iwata T, Matsumoto S (1977) Studies on the urinary metabolites of isophosphamide and its activated species in rabbits. Chem Pharm Bull 25: 2900-2909.
    • (1977) Chem Pharm Bull , vol.25 , pp. 2900-2909
    • Takamizawa, A.1    Iwata, T.2    Matsumoto, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.