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Volumn 30, Issue 4, 2004, Pages 311-318

Aldosterone and anti-aldosterone effects in cardiovascular diseases and diabetic nephropathy

Author keywords

Aldosterone; Cardiac hormones; Diabetic nephropathy; Heart failure; Renin angiotensin system

Indexed keywords

ALDOSTERONE; ALDOSTERONE RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; HORMONE RECEPTOR BLOCKING AGENT; POTASSIUM; SCLEROPROTEIN; SPIRONOLACTONE; UNCLASSIFIED DRUG;

EID: 4644278371     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1262-3636(07)70122-2     Document Type: Review
Times cited : (13)

References (53)
  • 1
    • 0033517358 scopus 로고    scopus 로고
    • Aldosterone and spironolactone in heart failure
    • Weber KT. Aldosterone and spironolactone in heart failure. N Engl J Med, 1999, 341, 753-5.
    • (1999) N Engl J Med , vol.341 , pp. 753-755
    • Weber, K.T.1
  • 3
    • 0030939082 scopus 로고    scopus 로고
    • Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma
    • Rossi GP, Sacchetto A, Pavan E, et al. Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma. Circulation, 1997, 95, 1471-8.
    • (1997) Circulation , vol.95 , pp. 1471-1478
    • Rossi, G.P.1    Sacchetto, A.2    Pavan, E.3
  • 4
    • 0027227646 scopus 로고
    • Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism
    • Brilla C, Matsubara LS, Weber KT. Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism. J Mol Cell Cardiol, 1993, 125, 563-75.
    • (1993) J Mol Cell Cardiol , vol.125 , pp. 563-575
    • Brilla, C.1    Matsubara, L.S.2    Weber, K.T.3
  • 6
    • 0030809598 scopus 로고    scopus 로고
    • Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion
    • Sun Y, Ramires FJ, Weber KT. Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. Cardiovasc Res, 1997, 35, 138-47.
    • (1997) Cardiovasc Res , vol.35 , pp. 138-147
    • Sun, Y.1    Ramires, F.J.2    Weber, K.T.3
  • 7
    • 0037180412 scopus 로고    scopus 로고
    • Increased carotid wall elastic modulus and fibronectin in aldosterone-salt treated rats. Effects of Eplerenone
    • Lacolley P, Labat C, Pujol A, Delcayre C, Benetos A, Safar M. Increased carotid wall elastic modulus and fibronectin in aldosterone-salt treated rats. Effects of Eplerenone. Circulation, 2002, 106, 2848-53.
    • (2002) Circulation , vol.106 , pp. 2848-2853
    • Lacolley, P.1    Labat, C.2    Pujol, A.3    Delcayre, C.4    Benetos, A.5    Safar, M.6
  • 8
    • 0028914059 scopus 로고
    • "Escape" of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: Implications for therapy
    • Pitt B. "Escape" of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: implications for therapy. Cardiovasc Drugs Ther, 1995, 9, 145-9.
    • (1995) Cardiovasc Drugs Ther , vol.9 , pp. 145-149
    • Pitt, B.1
  • 9
    • 0019946282 scopus 로고
    • Increase in plasma aldosterone during prolonged captopril treatment
    • Lijnen PM, Staessen J, Fagard R, Amery A. Increase in plasma aldosterone during prolonged captopril treatment. Am J Cardiol, 1982, 49, 1561-3.
    • (1982) Am J Cardiol , vol.49 , pp. 1561-1563
    • Lijnen, P.M.1    Staessen, J.2    Fagard, R.3    Amery, A.4
  • 10
    • 0037222490 scopus 로고    scopus 로고
    • Effectiveness of aldosterone blockade in patients with diabetic nephropathy
    • Sato A, Hayashi K, Naruse M, Saruta T. Effectiveness of aldosterone blockade in patients with diabetic nephropathy, Hypertension, 2003, 41, 64-8.
    • (2003) Hypertension , vol.41 , pp. 64-68
    • Sato, A.1    Hayashi, K.2    Naruse, M.3    Saruta, T.4
  • 11
    • 0023620145 scopus 로고
    • Efficacy and tolerance of spironolactone in essential hypertension
    • Jeunemaitre X, Chatellier G, Kreft-Jais C, et al. Efficacy and tolerance of spironolactone in essential hypertension. Am J Cardiol, 1988, 60, 820-5.
    • (1988) Am J Cardiol , vol.60 , pp. 820-825
    • Jeunemaitre, X.1    Chatellier, G.2    Kreft-Jais, C.3
  • 12
    • 2342511545 scopus 로고    scopus 로고
    • The 45-year story of the development of an anti-aldosterone more specific than spironolactone
    • in press
    • Menard J. The 45-year story of the development of an anti-aldosterone more specific than spironolactone. Mol Cell Biochem, 2004, in press.
    • (2004) Mol Cell Biochem
    • Menard, J.1
  • 13
    • 0035997359 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension
    • Weinberger MH, Roniker B, Krause SL, Weiss RJ. Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension. Am J Hypertens, 2002, 15, 709-16.
    • (2002) Am J Hypertens , vol.15 , pp. 709-716
    • Weinberger, M.H.1    Roniker, B.2    Krause, S.L.3    Weiss, R.J.4
  • 14
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Pitt B, Zannad F, Remme WJ, et al., for the Randomized ALdactone Evaluation Study Investigators. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. New Engl J Med, 1999, 341, 709-17.
    • (1999) New Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 15
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellulat matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the Randomized Aldactone Evaluation Study (RALES)
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B. Limitation of Excessive Extracellulat Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure: Insights From the Randomized Aldactone Evaluation Study (RALES). Circulation, 2000, 102, 2700-6.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 16
    • 0032031528 scopus 로고    scopus 로고
    • Myocardial fibrosis associated with Aldo or angiotensin II administration: Attenuation by calcium channel blockade
    • Ramires FJA, Sun Y, Weber KT. Myocardial fibrosis associated with Aldo or angiotensin II administration: attenuation by calcium channel blockade. J Mol Cell Cardiol, 1998, 30, 475-83.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 475-483
    • Ramires, F.J.A.1    Sun, Y.2    Weber, K.T.3
  • 17
    • 0035370038 scopus 로고    scopus 로고
    • Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure
    • Yee KM, Pringle SD, Struthers AD. Circadian variation in the effects of aldosterone blockade on heart rate variability and QT dispersion in congestive heart failure. J Am Coll Cardiol, 2001, 37, 1800-7.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1800-1807
    • Yee, K.M.1    Pringle, S.D.2    Struthers, A.D.3
  • 18
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation, 2000, 101, 594-7.
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 19
    • 0142085752 scopus 로고    scopus 로고
    • Effects of eplerenone, enalapril and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy. The 4E-LeFt Ventricular Hypertrophy Study
    • Pitt B, Reichek N, Willenbrock R, et al. Effects of eplerenone, enalapril and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy. The 4E-LeFt Ventricular Hypertrophy Study. Circulation, 2003, 108, 1831-8.
    • (2003) Circulation , vol.108 , pp. 1831-1838
    • Pitt, B.1    Reichek, N.2    Willenbrock, R.3
  • 20
    • 0242543981 scopus 로고    scopus 로고
    • Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction
    • Fraccarollo D, Galuppo P, Hildemann S, Christ M, Ertl G, Bauersachs J. Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction. J Am Coll Cardiol, 2003, 42, 1674-6.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1674-1676
    • Fraccarollo, D.1    Galuppo, P.2    Hildemann, S.3    Christ, M.4    Ertl, G.5    Bauersachs, J.6
  • 21
    • 0027174837 scopus 로고
    • Evidence that primary aldosteronism may not be uncommon: Twelve percent incidence among antihypertensive drug trial volunteers
    • Gordon RD, Ziesak MD, Tunny TJ, Stowasser M, Klemm SA. Evidence that primary aldosteronism may not be uncommon: twelve percent incidence among antihypertensive drug trial volunteers. Clin Exp Pharmacol Physiol, 1993, 20, 296-8.
    • (1993) Clin Exp Pharmacol Physiol , vol.20 , pp. 296-298
    • Gordon, R.D.1    Ziesak, M.D.2    Tunny, T.J.3    Stowasser, M.4    Klemm, S.A.5
  • 22
    • 0029558829 scopus 로고
    • Albuminuria in untreated patients with primari aldosteronism or essential hypertension
    • Halimi JM, Mimram A. Albuminuria in untreated patients with primari aldosteronism or essential hypertension. J Hypertens, 1995, 13, 1801-2.
    • (1995) J Hypertens , vol.13 , pp. 1801-1802
    • Halimi, J.M.1    Mimram, A.2
  • 23
    • 0033044504 scopus 로고    scopus 로고
    • Cardiovascular complications in patients with primary aldosteronism
    • Nishimura M, Uzu T, Fuji T, et al. Cardiovascular complications in patients with primary aldosteronism. Am J Kidney Dis, 1999, 33, 261-6.
    • (1999) Am J Kidney Dis , vol.33 , pp. 261-266
    • Nishimura, M.1    Uzu, T.2    Fuji, T.3
  • 24
    • 0038673178 scopus 로고    scopus 로고
    • Effects of selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension
    • White WB, Duprez D, St Hillaire R, et al. Effects of selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension. Hypertension, 2003, 41, 1021-6.
    • (2003) Hypertension , vol.41 , pp. 1021-1026
    • White, W.B.1    Duprez, D.2    St. Hillaire, R.3
  • 25
    • 0035027569 scopus 로고    scopus 로고
    • High serum level of procollagen type III amino-terminal peptide contributes to the efficacy of spironolactone and angiotensin-converting enzyme inhibitor therapy on left ventricular hypertrophy in essential hypertensive patients
    • Sato A, Takane H, Saruta T. High serum level of procollagen type III amino-terminal peptide contributes to the efficacy of spironolactone and angiotensin-converting enzyme inhibitor therapy on left ventricular hypertrophy in essential hypertensive patients. Hypertens Res, 2001, 24, 99-104.
    • (2001) Hypertens Res , vol.24 , pp. 99-104
    • Sato, A.1    Takane, H.2    Saruta, T.3
  • 26
    • 0036841840 scopus 로고    scopus 로고
    • Aldosterone antagonist improves diastolic function in essential hypertension
    • Grandi AM, Imperiale D, Santillo R, et al. Aldosterone antagonist improves diastolic function in essential hypertension. Hypertension, 2002, 40, 647-52.
    • (2002) Hypertension , vol.40 , pp. 647-652
    • Grandi, A.M.1    Imperiale, D.2    Santillo, R.3
  • 27
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, et al. Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial infarction. N Engl J Med, 2003, 348, 1309-21.
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 28
    • 0042320418 scopus 로고    scopus 로고
    • Aldosterone in chronic kidney and cardiac disease
    • Hostetter TH, Ibrahim HN. Aldosterone in chronic kidney and cardiac disease. J Am Soc Nephrol, 2003, 14, 2395-401.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2395-2401
    • Hostetter, T.H.1    Ibrahim, H.N.2
  • 29
    • 0035124068 scopus 로고    scopus 로고
    • Late escape from the antiproteinuric effect of ACE inhibitors in nondiabetic renal disease
    • Shiigai T, Shichiri M. Late escape from the antiproteinuric effect of ACE inhibitors in nondiabetic renal disease. Am J Kidney Dis, 2001, 37, 477-83.
    • (2001) Am J Kidney Dis , vol.37 , pp. 477-483
    • Shiigai, T.1    Shichiri, M.2
  • 30
    • 0001847493 scopus 로고    scopus 로고
    • Antiproteinuric efficacy of eplerenone, enalapril and eplerenone/enalapril combination in diabetic hypertensives with microalbuminuria
    • abstract
    • Epstein M, Buckalew V, Martinez F, et al. Antiproteinuric efficacy of eplerenone, enalapril and eplerenone/enalapril combination in diabetic hypertensives with microalbuminuria. Am J Hypertens, 2002, 15, 24A (abstract).
    • (2002) Am J Hypertens , vol.15
    • Epstein, M.1    Buckalew, V.2    Martinez, F.3
  • 31
    • 0032588244 scopus 로고    scopus 로고
    • Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: Role in aldosterone-salt-induced fibrosis
    • Robert V, Heymes C, Silvestre J, Sabri A, Swynghedauw B, Delcayre C. Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: role in aldosterone-salt-induced fibrosis. Hypertension, 1999, 33, 981-6.
    • (1999) Hypertension , vol.33 , pp. 981-986
    • Robert, V.1    Heymes, C.2    Silvestre, J.3    Sabri, A.4    Swynghedauw, B.5    Delcayre, C.6
  • 32
    • 0022337756 scopus 로고
    • Effect of aldosterone on vascular angiotensin II receptors in the rat
    • Schiffrin EL, Franks DJ, Gutkowska J. Effect of aldosterone on vascular angiotensin II receptors in the rat. Can J Physiol Pharmacol, 1985, 63, 1522-7.
    • (1985) Can J Physiol Pharmacol , vol.63 , pp. 1522-1527
    • Schiffrin, E.L.1    Franks, D.J.2    Gutkowska, J.3
  • 33
    • 0031600240 scopus 로고    scopus 로고
    • Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats
    • Rocha R, Chander PN, Khanna K, Zuckerman A, Stier Jr CT. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension, 1998, 31, 451-8.
    • (1998) Hypertension , vol.31 , pp. 451-458
    • Rocha, R.1    Chander, P.N.2    Khanna, K.3    Zuckerman, A.4    Stier Jr., C.T.5
  • 34
    • 0029810416 scopus 로고    scopus 로고
    • Role of aldosterone in the remnant kidney model in the rat
    • Greene EL, Kren S, Hostetter TH. Role of aldosterone in the remnant kidney model in the rat. J Clin Invest, 1996, 98, 1063-8.
    • (1996) J Clin Invest , vol.98 , pp. 1063-1068
    • Greene, E.L.1    Kren, S.2    Hostetter, T.H.3
  • 35
    • 0033745021 scopus 로고    scopus 로고
    • Aldosterone: A mediator of myocardial necrosis and renal injury
    • Rocha R, Stier CT Jr, Kifor I, et al. Aldosterone: a mediator of myocardial necrosis and renal injury. Endocrinology, 2000, 141, 3871-8.
    • (2000) Endocrinology , vol.141 , pp. 3871-3878
    • Rocha, R.1    Stier Jr., C.T.2    Kifor, I.3
  • 38
    • 0032996757 scopus 로고    scopus 로고
    • Cardiac fibrosis and inflammation: Interaction with hemodynamic and hormonal factors
    • Nicoletti A, Michel JB. Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors. Cardiovasc Res, 1999, 41, 532-43.
    • (1999) Cardiovasc Res , vol.41 , pp. 532-543
    • Nicoletti, A.1    Michel, J.B.2
  • 39
    • 0036791717 scopus 로고    scopus 로고
    • Spironolactone improves angiotensin-induced vascular changes and oxidative stress
    • Virais A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL. Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension, 2002, 40, 504-10.
    • (2002) Hypertension , vol.40 , pp. 504-510
    • Virais, A.1    Neves, M.F.2    Amiri, F.3    Viel, E.4    Touyz, R.M.5    Schiffrin, E.L.6
  • 40
    • 0038206805 scopus 로고    scopus 로고
    • Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: Effect on endothelial dysfunction
    • Schafer A, Fraccarollo D, Hildemann SK, Tas P, Ertl G, Bauersachs J. Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: effect on endothelial dysfunction. Cardiovasc Res, 2003, 58, 655-62.
    • (2003) Cardiovasc Res , vol.58 , pp. 655-662
    • Schafer, A.1    Fraccarollo, D.2    Hildemann, S.K.3    Tas, P.4    Ertl, G.5    Bauersachs, J.6
  • 41
    • 0037373553 scopus 로고    scopus 로고
    • Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: Effects of 11 beta-hydroxysteroid dehydrogenase inactivation
    • Young MJ, Moussa L, Dilley R, Funder JW. Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. Endocrinology, 2003, 144, 1121-5.
    • (2003) Endocrinology , vol.144 , pp. 1121-1125
    • Young, M.J.1    Moussa, L.2    Dilley, R.3    Funder, J.W.4
  • 42
    • 0038299329 scopus 로고    scopus 로고
    • Aldosteronism: An immunostimulatory state precedes proinflammatory/ fibrogenic cardiac phenotype
    • Gerling IC, Sun Y, Ahokas RA, et al. Aldosteronism: an immunostimulatory state precedes proinflammatory/fibrogenic cardiac phenotype. Am J Physiol Heart Circ Physiol, 2003, 285, H813-21.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Gerling, I.C.1    Sun, Y.2    Ahokas, R.A.3
  • 43
    • 0032570807 scopus 로고    scopus 로고
    • Myocardial production of aldosterone and corticosterone in the rat. Physiological Regulations
    • Silvestre JS, Robert V, Heymes C, et al. Myocardial production of aldosterone and corticosterone in the rat. Physiological Regulations. J Biol Chem, 1998, 273, 4883-91.
    • (1998) J Biol Chem , vol.273 , pp. 4883-4891
    • Silvestre, J.S.1    Robert, V.2    Heymes, C.3
  • 44
    • 0027997406 scopus 로고
    • Vascular Aldo. Biosynthesis and a link to angiotensin II induced hypertrophy of vascular smooth muscle cells
    • Hatakeyama H, Miyamori I, Fujita T, Takeda Y, Takeda R, Yamamoto H. Vascular Aldo. Biosynthesis and a link to angiotensin II induced hypertrophy of vascular smooth muscle cells. J Biol Chem, 1994, 269, 24316-20.
    • (1994) J Biol Chem , vol.269 , pp. 24316-24320
    • Hatakeyama, H.1    Miyamori, I.2    Fujita, T.3    Takeda, Y.4    Takeda, R.5    Yamamoto, H.6
  • 45
    • 0037734060 scopus 로고    scopus 로고
    • Expression and modulation of the Steroidogenic Acute Regulatory (StAR) protein mRNA in rat cardiocytes and after myocardial infarction
    • Casal AJ, Silvestre JS, Delcayre C, Capponi AM. Expression and modulation of the Steroidogenic Acute Regulatory (StAR) protein mRNA in rat cardiocytes and after myocardial infarction. Endocrinology, 2003, 144, 1861-8.
    • (2003) Endocrinology , vol.144 , pp. 1861-1868
    • Casal, A.J.1    Silvestre, J.S.2    Delcayre, C.3    Capponi, A.M.4
  • 46
    • 0033602819 scopus 로고    scopus 로고
    • Activation of cardiac aldosterone production in rat myocardial infarction. Effect of angiotensin II receptor blockade and role in cardiac fibrosis
    • Silvestre J, Heymes C, Oubenaissa A, et al. Activation of cardiac aldosterone production in rat myocardial infarction. Effect of angiotensin II receptor blockade and role in cardiac fibrosis. Circulation, 1999, 99, 2694-701.
    • (1999) Circulation , vol.99 , pp. 2694-2701
    • Silvestre, J.1    Heymes, C.2    Oubenaissa, A.3
  • 47
    • 0036911129 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling. The role of aldosterone
    • Delcayre C, Swynghedauw B. Molecular mechanisms of myocardial remodeling. The role of aldosterone. J Mol Cell Cardiol, 2002, 34, 1577-84.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1577-1584
    • Delcayre, C.1    Swynghedauw, B.2
  • 48
    • 0035830440 scopus 로고    scopus 로고
    • Aldosterone production is activated in failing ventricle in humans
    • Mizuno Y, Yoshimura M, Yasue H, et al. Aldosterone production is activated in failing ventricle in humans. Circulation, 2001, 103, 72-7.
    • (2001) Circulation , vol.103 , pp. 72-77
    • Mizuno, Y.1    Yoshimura, M.2    Yasue, H.3
  • 49
    • 0038343383 scopus 로고    scopus 로고
    • Aldosterone: Direct effects on and production by the heart
    • White PC. Aldosterone: direct effects on and production by the heart. J Clin Endocrinol Metab, 2003, 88, 2376-83.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2376-2383
    • White, P.C.1
  • 50
    • 12144288228 scopus 로고    scopus 로고
    • Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy
    • Tsybouleva N, Zhang L, Chen S, et al. Aldosterone, Through Novel Signaling Proteins, Is a Fundamental Molecular Bridge Between the Genetic Defect and the Cardiac Phenotype of Hypertrophic Cardiomyopathy. Circulation, 2004, 109, 1284-91.
    • (2004) Circulation , vol.109 , pp. 1284-1291
    • Tsybouleva, N.1    Zhang, L.2    Chen, S.3
  • 51
    • 0031054580 scopus 로고    scopus 로고
    • Glucocorticoid and mineralocorticoid receptors: Biology and clinical relevance
    • Funder JW. Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance. Annu Rev Med, 1997, 48, 231-40.
    • (1997) Annu Rev Med , vol.48 , pp. 231-240
    • Funder, J.W.1
  • 52
    • 0037488488 scopus 로고    scopus 로고
    • Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure
    • Qin W, Rudolph AE, Bond BR, et al. Transgenic Model of Aldosterone-Driven Cardiac Hypertrophy and Heart Failure. Circ Res, 2003, 93, 69-76.
    • (2003) Circ Res , vol.93 , pp. 69-76
    • Qin, W.1    Rudolph, A.E.2    Bond, B.R.3
  • 53
    • 0037076296 scopus 로고    scopus 로고
    • Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes
    • Beggah AT, Escoubet B, Puttini S, et al. Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes. Proc Natl Acad Sci USA, 2002, 99, 7160-5.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7160-7165
    • Beggah, A.T.1    Escoubet, B.2    Puttini, S.3


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