Gene-transferring efficiencies of novel diamino cationic lipids with varied hydrocarbon chains

Bioconjugate Chemistry

Volumn 15, Issue 5, 2004, Pages 1095-1101

  Kim, Hong Sung ^a   Moon, Jaeho ^a   Kim, Keun Sik ^a   Choi, Myung Min ^a   Lee, Ji Eun ^a   Heo, Yeon ^a   Cho, Dae Hyan ^a   Jang, Doo Ok ^a   Park, Yong Serk ^a  

^a Yonsei University Wonju   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; BIOCOMPATIBILITY; CHAINS; EFFICIENCY; HYDROCARBONS; LIPIDS; LIPOSOMES;

CATIONIC LIPIDS; EXPERIMENTAL CONDITIONS; GENE TRANSFECTION; HYDROCARBON CHAIN LENGTH; HYDROCARBON CHAINS; KIDNEY CELLS; MELANOMA CELLS; PHOSPHATIDYLETHANOLAMINE; SYNTHESISED; TRANSFECTION EFFICIENCY;

GENES;

CATION; DIAMINO ACID; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; HYDROCARBON; LIPOSOME; LYSINE; VIRUS VECTOR;

AQUEOUS SOLUTION; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CELL TRANSFORMATION; COMPLEX FORMATION; DNA BINDING; DNA VECTOR; GENE TRANSFER; GENETIC TRANSFECTION; HYDROPHOBICITY; INTERNALIZATION; KIDNEY CELL; MELANOMA CELL; NONVIRAL GENE DELIVERY SYSTEM; RECEPTOR AFFINITY;

EID: 4644260479     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc049934t     Document Type: Article

References (21)

1. Huang, L., and Viroonchatanpan, E. (1999) Nonviral vectors for gene therapy (Huang, L., et al., Eds.) pp 3-22, Academic Press, San Diego, CA.
2. Lasic, D. D. (1999) Nonviral vectors for gene therapy (Huang, L., et al., Eds.) pp 69-89, Academic Press, San Diego, CA.
3. Hui, K. M., Ang, P. T., Huang, L., and Tay, S. K. (1997) Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Ther. 8 783-790.
4. Rini, B. I., Selk, L. M., and Vogelzang, N. J. (1999) Phase I study of direct intralesional gene transfer of HLA-B7 into metastatic renal carcinoma lesions, Clin. Cancer Res. 5, 2766-2772.
5. Hyde, S. C., Southern, K. W., Gileadi, U., Fitzjohn, E. M., Mofford, K. A., Waddell, B. E., Gooi, H. C., Goddard, C. A., Hannavy, K., Smyth, S. E., Egan, J. J., Sorgi, F. L., Huang, L., Cuthbert, A. W., Evans, M. J., Colledge, W. H., Higgins, C. F., Webb, A. K., and Gill, D. R. (2000) Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther. 7, 1156-1165.
6. Noone, P. G., Hohneker, K. W., Zhou, Z., Johnson, L. G., Foy, C., Gipson, C., Jones, K., Noah, T. L., Leigh, M. W., Schwartzbach, C., Efthimiou, J., Pearlman, R., Boucher, R. C., and Knowles, M. R. (2000) Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis. Mol. Ther. 1, 105-114.
7. Liu, D., Ren, T., and Gao, X. (2003) Cationic transfection lipids. Curr. Med. Chem. 10, 1005-1013.
8. Hofland, H. E., Masson, C., Iginla, S., Osetinsky, I., Reddy, J. A., Leamon, C. P., Scherman, D., Bessodes, M., and Wils, P. (2002) Folate-targeted gene transfer in vivo. Mol. Ther. 5, 739-744.
9. Stewart, M. J., Plautz, G. E., Del Buono, L., Yang, Z. Y., Xu, L., Gao, X., Huang, L., Nabel, E. G., and Nabel, G. J. (1992) Gene transfer in vivo with DA-liposome complexes: Safety and acuty toxicity in mice. Hum. Gene Ther. 3, 267-275.
10. Song, Y. K., Liu, F., Chu, S., and Liu, D. (1997) Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration. Hum. Gene Ther. 8, 1585-1594.
11. Choi, J. S., Lee, E. J., Jang, H. S., and Park, J. S. (2001) New cationic liposomes for gene transfer into mammalian cells with high efficiency and low toxicity. Bioconjugate Chem. 12, 108-113.
12. Carmichael, J., deGraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchel, J. B. (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radio sensitivity. Cancer Res. 47, 936-942.
13. Hui, S. W., Langner, M., Zhao, Y. L., Ross, P., Hurley, E., and Chan, K. (1996) The role of helper lipids in cationic liposome-mediated gene transfer. Biophys. J. 71, 590-599.
14. Feigner, P. L., Gadek, T. R., Holm, M., Roman, R., Chan, H. W., Wenz, M., Northrop, J. P., Ringold, G. M., and Danielsen, M. (1987) Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. U.S.A. 84, 7413-7417.
15. Feigner, J. H., Kumar, R., Sridhar, C. N., Wheeler, C. J., Tsai, Y. J., Border, R., Ramsey, P., Martin, M., and Feigner, P. L. (1994) Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J. Biol. Chem. 269, 2550-2561.
16. Tilcock, C. P. (1986) Lipid polymorphism. Chem. Phys. Lipids 40, 109-125.
17. Smisterova, J., Wagenaar, A., Stuart, M. C., Polushkin, E., ten Brinke, G., Hulst, R., Engberts, J. B., and Hoekstra, D. (2001) Molecular shape of the cationic lipid controls the structure of cationic lipid/ dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery. J. Biol. Chem. 276, 47615-47622.
18. II phase and the contact-induced destabilization of phosphatidylethanolamine-containing membranes. Proc. Natl. Acad. Sci. U.S.A. 82, 5742-5745.
19. Spector, A. A., and Yorek, M. A. (1985) Membrane lipid composition and cellular function. J. Lipid Res. 26, 1015-1035.
20. Li, S., Tseng, W. C., Stolz, D. B., Wu, S. P., Watkins, S. C., and Huang, L. (1999) Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther. 6, 585-594.
21. Regelin, A. E., Fankhaenel, S., Gurtesch, L., Prinz, C., von Kiedrowski, G., and Massing, U. (2000) Biophysical and lipofection studies of DOTAP analogues. Biochim. Biophys. Acta 1464, 151-164.