Refining the intestinal motility test in mice to reduce animal stress

Revista de Ciencias Farmaceuticas

Volumn 24, Issue 1, 2003, Pages 79-82

  Marona, H R N ^a   Lucchesi, M B B ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Animal welfare; In vivo test; Intestinal motility; Loperamide; Mice

Indexed keywords

LOPERAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL STRESS; ANIMAL TESTING REDUCTION; ANIMAL TESTING REFINEMENT; ANIMAL TESTING REPLACEMENT; ANIMAL TISSUE; ANIMAL WELFARE; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; DIAGNOSTIC TEST; DIET RESTRICTION; FUNCTION TEST; IN VIVO STUDY; INTESTINE MOTILITY; INTESTINE MOTILITY TEST; MOUSE; MOUSE STRAIN; NONHUMAN; PRACTICE GUIDELINE; STRESS;

EID: 4644251922     PISSN: 01013793     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. AKAH, P.A. at. al. Evaluation of Nigerian traditional medicines: II. Effects of some Nigerian folk remedies on peptic ulcer. J. Ethnopharmacol, v.62, p. 123-127, 1998.
2. AWIC. Food deprivation or water deprivation. Guidelines for diet control in behavioral studies. 2002. Disponível em: www.nal.usa/gov/awic/pubs/ IACUC/ food.htm. Acesso em: 19.03.2003.
3. BALCOMBE, J. The use of animals in higher education. Washington, Human Society Press, 2000.
4. nd ed. Washington:USDA, 1994. Disponível em: www.nal.usa/gov/awic/pubs/noawicpubs/ essentia.htm Acesso em 19.03.2003.
5. DAS, A.K. at al. Studies on antidiarrhoeal activity of Punica granatum seed extract in rats. J. Ethnopharmacol., v.68, p.205-208, 1999.
6. DOBSON, H. at al. Is stress really all that important? Theriogenology, v.55, p.65-73, 2001.
7. th ed. New York: McGraw-Hill, 1996.
8. ILAR. Guide for the care and use of laboratory animals. Washington, National Academic Press, 1996.
9. KUMAR, S.at al. Anti-diarrhoeal activity of the latex of Calotropis procera. J. Ethnopharmacol., v.76 p.115-118, 2001.
10. LIN, J.; PUCKREE, T.; MVELASE, T.P. Anti-diarrhoeal evaluation of some medicinal plants used by Zulu traditional healers. J.Ethnopharmacol., v.79, p.53-56, 2002.
11. MÄLKKI, Y.; VIRTANEN, E. Gastrointestinal effects of oat bran and oat gum. A review. Lebensm. Wiss. Technol., v.34, p.33-347, 2001.
12. OFFIAH, V.N.; CHIKWENDU, U.A. Antidiarrhoeal effects of Ocimum gratissimum leaf extract in experimental animals. J. Ethnopharmacol., v.68, p.327-330, 1999.
13. OLAJIDE, O.A. et al. Pharmacological studies on the leaf of Psidium guajava. Fitoterapia, v.70, p.25-31, 1999.
14. PAUL, R.K.; JABBAR, A., RASHID, M.A. Antiulcer activity of Mikania cordata. Fitoterapia, v.71, p.701-703, 2000.
15. PETTO, A.J.; RUSSEL, K.D. Human education: The role of animal-based learning. In: DOLLINS, F.L. (Ed.). Attitudes to animals: views in animal welfare. Cambridge, Cambridge University, 1999.
16. RANI, S.at al.Anti-diarrhoeal of Clerodendrum phlomidis Linn, leaf extract in rats. J. Ethnopharmacol., v.68, p.315-319, 1999.
17. RIVERA, E.A.B. Estresse em Animais de Laboratório. In: ANDRADE, A.; PINTO, S.C.; OLIVEIRA, R.S. (Org.) Animais de laboratório: criação e experimentação. Rio de Janeiro: Fiocruz, 2002. p.263-273.
18. SAIRAM, K. et al. Evaluation of anti-diarrhoeal activity in seed extracts of Mangifera indica. J. Ethnopharmacol., v.84, p.11-15, 2003.
19. SALAH, A.M.; GATHUMBI, J.; VIERLING, W. Inhibition of intestinal motility by methanol extracts of Hibiscus sabdariffa L. (Malvaceae) in rats. Phytochem. Res., v. 16, n.3, p.283-285, 2002.
20. SANTOS, F.A.; RAO, V.S.N. Some observations on the gastrointestinal effects of eucalyptol (1.8-cineole). In: VIPHARMATECH, Recife, 2001.p.143.
21. VAN LOO, P.L.P.at al. Modulation of aggression in male mice: influence of group size and cage size. Physiology & Behavior, v.72, p.675-683, 2001.
22. VAN ZUTPHEN, L. F. M.; VAN DER VALK, J. B. F. Developments on the implementation of the Three Rs in research and education. Toxicol. Vitro, v. 15, p.591-595, 2001.
23. VERMEULEN, J.K.at al. Food deprivation: common sense or nonsense? Animal Technol,. v.48, n.2, p.45-54, 1997.
24. WILSON, K.F.; GOOSSENS, D.J. A computational model of gastro-intestinal motility. Comp. Phys. Commun., v. 142, p. 105-108, 2001.
25. YU, L.-L.; LIAO, J.-F.; CHEN, C.-F. Anti-diarrhoeal effect of water extract of Evodiae fructus in mice. J. Ethnopharmacol., v.73, p.39-45, 2000.