Ultrasensitive electrocatalytic DNA detection at two- and three-dimensional nanoelectrodes

Journal of the American Chemical Society

Volumn 126, Issue 39, 2004, Pages 12270-12271

  Gasparac, Rahela ^a   Taft, Bradford J ^a   Lapierre Devlin, Melissa A ^a   Lazareck, Adam D ^b   Xu, Jimmy M ^b   Kelley, Shana O ^a  

^a BOSTON COLLEGE   (United States)

^b Brown University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GOLD; OLIGONUCLEOTIDE; POLYCARBONATE;

ARTICLE; BIOSENSOR; CYCLIC POTENTIOMETRY; DNA DETERMINATION; DNA HYBRIDIZATION; DNA PROBE; ELECTROCHEMISTRY; ELECTRODE; ELECTRONICS; NANOELECTRODE; SCANNING ELECTRON MICROSCOPY;

BIOSENSING TECHNIQUES; CATALYSIS; CATIONS; DNA; ELECTROCHEMISTRY; FERRIC COMPOUNDS; GOLD; HELICOBACTER PYLORI; MICROELECTRODES; MICROSCOPY, ELECTRON, SCANNING; NANOTECHNOLOGY; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDES; RNA, RIBOSOMAL, 23S; RUTHENIUM; SENSITIVITY AND SPECIFICITY;

EID: 4644238631     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0458221     Document Type: Article

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13. 2), on the basis of areas approximated from SEM images. However, depletion of the diffusion layer between adjacent 3D nano-structures has previously been observed to decrease the participation of exposed sidewalls in electrochemical processes.3 This effect may be responsible for the relatively small signal increases that are observed at 3D relative to 2D NEEs in our assay.
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