메뉴 건너뛰기




Volumn 53, Issue 6, 2004, Pages 1709-1719

Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE TOXIN; CALCIUM; CD11B ANTIGEN; CYCLIC AMP; GLYCOPROTEIN E; HEMAGGLUTININ; MONOCLONAL ANTIBODY; TRYPSIN;

EID: 4644227794     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04227.x     Document Type: Article
Times cited : (52)

References (51)
  • 1
    • 0025965870 scopus 로고
    • Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation
    • Barry, E.M., Weiss, A.A., Ehrmann, I.E., Gray, M.C., Hewlett, E.L., and Goodwin, M.S. (1991) Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation. J Bacteriol 173: 720-726.
    • (1991) J Bacteriol , vol.173 , pp. 720-726
    • Barry, E.M.1    Weiss, A.A.2    Ehrmann, I.E.3    Gray, M.C.4    Hewlett, E.L.5    Goodwin, M.S.6
  • 3
    • 0019973678 scopus 로고
    • Phagocyte impotence caused by an invasive bacterial adenylate cyclase
    • Confer, D.L., and Eaton, J.W. (1982) Phagocyte impotence caused by an invasive bacterial adenylate cyclase. Science 217: 948-950.
    • (1982) Science , vol.217 , pp. 948-950
    • Confer, D.L.1    Eaton, J.W.2
  • 4
    • 0021297432 scopus 로고
    • Bordetella adenylate cyclase toxin: Entry of bacterial adenylate cyclase into mammalian cells
    • Confer, D.L., Slungaard, A.S., Graf, E., Panter, S.S., and Eaton, J.W. (1984) Bordetella adenylate cyclase toxin: entry of bacterial adenylate cyclase into mammalian cells. Adv Cyclic Nucl Prot 17: 183-187.
    • (1984) Adv Cyclic Nucl Prot , vol.17 , pp. 183-187
    • Confer, D.L.1    Slungaard, A.S.2    Graf, E.3    Panter, S.S.4    Eaton, J.W.5
  • 5
    • 0026816008 scopus 로고
    • Structural and functional relationships among the RTX toxin determinants of gram-negative bacteria
    • Coote, J.G. (1992) Structural and functional relationships among the RTX toxin determinants of gram-negative bacteria. FEMS Microbiol Rev 88: 137-162.
    • (1992) FEMS Microbiol Rev , vol.88 , pp. 137-162
    • Coote, J.G.1
  • 6
    • 0026649632 scopus 로고
    • Enzymatic activity of adenylate cyclase toxin from Bordetella pertussis is not required for hemolysis
    • Ehrmann, I.E., Weiss, A.A., Goodwin, M.S., Gray, M.C., Barry, E., and Hewlett, E.L. (1992) Enzymatic activity of adenylate cyclase toxin from Bordetella pertussis is not required for hemolysis. FEBS 304: 51-56.
    • (1992) FEBS , vol.304 , pp. 51-56
    • Ehrmann, I.E.1    Weiss, A.A.2    Goodwin, M.S.3    Gray, M.C.4    Barry, E.5    Hewlett, E.L.6
  • 7
    • 1842843188 scopus 로고    scopus 로고
    • High level expression of His-tagged colicin pore-forming domains and reflections on the sites for pore formation in the inner membrane
    • Fridd, S.L., Gokce, I., and Lakey, J.H. (2002) High level expression of His-tagged colicin pore-forming domains and reflections on the sites for pore formation in the inner membrane. Biochimie 84: 477-483.
    • (2002) Biochimie , vol.84 , pp. 477-483
    • Fridd, S.L.1    Gokce, I.2    Lakey, J.H.3
  • 8
    • 0023074159 scopus 로고
    • Bordetella pertussis adenylate cyclase: Isolation and purification by calmodulin-sepharose 4B chromatography
    • Friedman, R.L. (1987) Bordetella pertussis adenylate cyclase: isolation and purification by calmodulin-sepharose 4B chromatography. Infect Immun 55: 129-134.
    • (1987) Infect Immun , vol.55 , pp. 129-134
    • Friedman, R.L.1
  • 9
    • 0023088297 scopus 로고
    • Bordetella pertussis adenylate cyclase: Effects of affinity-purified adenylate cyclase on human polymorphonuclear leukocyte functions
    • Friedman, R.L., Fiederlein, R.L., Glasser, L., and Galgiani, J.N. (1987) Bordetella pertussis adenylate cyclase: effects of affinity-purified adenylate cyclase on human polymorphonuclear leukocyte functions. Infect Immun 55: 135-140.
    • (1987) Infect Immun , vol.55 , pp. 135-140
    • Friedman, R.L.1    Fiederlein, R.L.2    Glasser, L.3    Galgiani, J.N.4
  • 11
    • 0024195829 scopus 로고
    • Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis
    • Glaser, P., Sakamoto, H., Bellalou, J., Ullmann, A., and Danchin, A. (1988b) Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis. EMBO J 7: 3997-4004.
    • (1988) EMBO J , vol.7 , pp. 3997-4004
    • Glaser, P.1    Sakamoto, H.2    Bellalou, J.3    Ullmann, A.4    Danchin, A.5
  • 12
    • 0025162502 scopus 로고
    • Adenylate cyclase toxin is critical for colonization and pertussis toxin is critical for lethal infection by Bordetella pertussis in infant mice
    • Goodwin, M.S., and Weiss, A.A. (1990) Adenylate cyclase toxin is critical for colonization and pertussis toxin is critical for lethal infection by Bordetella pertussis in infant mice. Infect Immun 58: 3445-3447.
    • (1990) Infect Immun , vol.58 , pp. 3445-3447
    • Goodwin, M.S.1    Weiss, A.A.2
  • 13
    • 0034805613 scopus 로고    scopus 로고
    • Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis
    • Gray, M.C., Lee, S.J., Gray, L.S., Zaretzky, F.R., Otero, A.S., Szabo, G., and Hewlett, E.L. (2001) Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis. J Bacteriol 183: 5904-5910.
    • (2001) J Bacteriol , vol.183 , pp. 5904-5910
    • Gray, M.C.1    Lee, S.J.2    Gray, L.S.3    Zaretzky, F.R.4    Otero, A.S.5    Szabo, G.6    Hewlett, E.L.7
  • 14
    • 0032813035 scopus 로고    scopus 로고
    • Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry
    • Gray, M.C., Ross, W., Kim, K.J., and Hewlett, E.L. (1999) Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry. Infect Immun 67: 4393-4399.
    • (1999) Infect Immun , vol.67 , pp. 4393-4399
    • Gray, M.C.1    Ross, W.2    Kim, K.J.3    Hewlett, E.L.4
  • 15
    • 0032541030 scopus 로고    scopus 로고
    • Distinct mechanisms for K+ efflux, intoxication, and hemolysis by Bordetella pertussis AC toxin
    • Gray, M., Szabo, G., Otero, A.S., Gray, L., and Hewlett, E. (1998) Distinct mechanisms for K+ efflux, intoxication, and hemolysis by Bordetella pertussis AC toxin. J Biol Chem 273: 18260-18267.
    • (1998) J Biol Chem , vol.273 , pp. 18260-18267
    • Gray, M.1    Szabo, G.2    Otero, A.S.3    Gray, L.4    Hewlett, E.5
  • 16
    • 0026750543 scopus 로고
    • Targeted mutations that ablate either the adenylate cyclase or hemolysin function of the bifunctional cyaA toxin of Bordetella pertussis abolish virulence
    • Gross, M.K., Au, D.C., Smith, A.L., and Storm, D.R. (1992) Targeted mutations that ablate either the adenylate cyclase or hemolysin function of the bifunctional cyaA toxin of Bordetella pertussis abolish virulence. Proc Natl Acad Sci USA 89: 4898-4902.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4898-4902
    • Gross, M.K.1    Au, D.C.2    Smith, A.L.3    Storm, D.R.4
  • 18
    • 0024423412 scopus 로고
    • Invasive adenylate cyclase toxin of Bordetella pertussis
    • Hanski, E. (1989) Invasive adenylate cyclase toxin of Bordetella pertussis. Trends Biochem Sci 14: 459-463.
    • (1989) Trends Biochem Sci , vol.14 , pp. 459-463
    • Hanski, E.1
  • 19
    • 0022262657 scopus 로고
    • Bordetella pertussis invasive adenylate cyclase. Partial resolution and properties of its cellular penetration
    • Hanski, E., and Farfel, Z. (1985) Bordetella pertussis invasive adenylate cyclase. Partial resolution and properties of its cellular penetration. J Biol Chem 280: 5526-5532.
    • (1985) J Biol Chem , vol.280 , pp. 5526-5532
    • Hanski, E.1    Farfel, Z.2
  • 20
    • 0032976371 scopus 로고    scopus 로고
    • Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity
    • Harvill, E.T., Cotter, P.A., Yuk, M.H., and Miller, J.F. (1999) Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. Infect Immun 67: 1493-1500.
    • (1999) Infect Immun , vol.67 , pp. 1493-1500
    • Harvill, E.T.1    Cotter, P.A.2    Yuk, M.H.3    Miller, J.F.4
  • 21
    • 0024807514 scopus 로고
    • Adenylate cyclase toxin from Bordetella pertussis. Identification and purification of the holotoxin molecule
    • Hewlett, E.L., Gordon, V.M., McCaffery, J.D., Sutherland, W.M., and Gray, M.C. (1989) Adenylate cyclase toxin from Bordetella pertussis. Identification and purification of the holotoxin molecule. J Biol Chem 264: 19379-19384.
    • (1989) J Biol Chem , vol.264 , pp. 19379-19384
    • Hewlett, E.L.1    Gordon, V.M.2    McCaffery, J.D.3    Sutherland, W.M.4    Gray, M.C.5
  • 22
    • 0026014158 scopus 로고
    • Adenylate cyclase toxin from Bordetella pertussis. Conformational change associated with toxin activity
    • Hewlett, E.L., Gray, L., Allietta, M., Ehrmann, I., Gordon, V.M., and Gray, M.C. (1991) Adenylate cyclase toxin from Bordetella pertussis. Conformational change associated with toxin activity. J Biol Chem 266: 17503-17508.
    • (1991) J Biol Chem , vol.266 , pp. 17503-17508
    • Hewlett, E.L.1    Gray, L.2    Allietta, M.3    Ehrmann, I.4    Gordon, V.M.5    Gray, M.C.6
  • 23
    • 0027536526 scopus 로고
    • Characterization of adenylate cyclase toxin from a mutant of Bordetella pertussis defective in the activator gene cyaC
    • Hewlett, E.L., Gray, M.C., Ehrmann, I.E., Maloney, N.J., Otero, A.S., Gray, L., et al. (1993) Characterization of adenylate cyclase toxin from a mutant of Bordetella pertussis defective in the activator gene cyaC. J Biol Chem 268: 7842-7848.
    • (1993) J Biol Chem , vol.268 , pp. 7842-7848
    • Hewlett, E.L.1    Gray, M.C.2    Ehrmann, I.E.3    Maloney, N.J.4    Otero, A.S.5    Gray, L.6
  • 25
    • 0017162911 scopus 로고
    • Soluble adenylate cyclase from the culture medium of Bordetella pertussis: Purification and characterization
    • Hewlett, E., and Wolff, J. (1976) Soluble adenylate cyclase from the culture medium of Bordetella pertussis: purification and characterization. J Bacteriol 127: 890-898.
    • (1976) J Bacteriol , vol.127 , pp. 890-898
    • Hewlett, E.1    Wolff, J.2
  • 26
    • 0028801091 scopus 로고
    • Identification by in vitro complementation of regions required for cell-invasive activity of Bordetella pertussis adenylate cyclase toxin
    • Iwaki, M., Ullmann, A., and Sebo, P. (1995) Identification by in vitro complementation of regions required for cell-invasive activity of Bordetella pertussis adenylate cyclase toxin. Mol Microbiol 17: 1015-1024.
    • (1995) Mol Microbiol , vol.17 , pp. 1015-1024
    • Iwaki, M.1    Ullmann, A.2    Sebo, P.3
  • 27
    • 0022534451 scopus 로고
    • Secreted adenylate cyclase of Bordetella pertussis: Calmodulin requirements and partial purification of two forms
    • Kessin, R.H., and Franke, J. (1986) Secreted adenylate cyclase of Bordetella pertussis: calmodulin requirements and partial purification of two forms. J Bacteriol 166: 290-296.
    • (1986) J Bacteriol , vol.166 , pp. 290-296
    • Kessin, R.H.1    Franke, J.2
  • 28
    • 0035163398 scopus 로고    scopus 로고
    • Internalization of Bordetella pertussis adenylate cyclase-haemolysin into endocytic vesicles contributes to macrophage cytotoxicity
    • Khelef, N., Gounon, P., and Guiso, N. (2001) Internalization of Bordetella pertussis adenylate cyclase-haemolysin into endocytic vesicles contributes to macrophage cytotoxicity. Cell Microbiol 3: 721-730.
    • (2001) Cell Microbiol , vol.3 , pp. 721-730
    • Khelef, N.1    Gounon, P.2    Guiso, N.3
  • 29
    • 0026831206 scopus 로고
    • Both adenylate cyclase and hemolytic activities are required by Bordetella pertussis to initiate infection
    • Khelef, N., Sakamoto, H., and Guiso, N. (1992) Both adenylate cyclase and hemolytic activities are required by Bordetella pertussis to initiate infection. Microb Pathog 12: 227-235.
    • (1992) Microb Pathog , vol.12 , pp. 227-235
    • Khelef, N.1    Sakamoto, H.2    Guiso, N.3
  • 30
    • 0027374664 scopus 로고
    • Bordetella pertussis induces apoptosis in macrophages: Role of adenylate cyclase-hemolysin
    • Khelef, N., Zychlinsky, A., and Guiso, N. (1993) Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase-hemolysin Infect Immun 61: 4064-4071.
    • (1993) Infect Immun , vol.61 , pp. 4064-4071
    • Khelef, N.1    Zychlinsky, A.2    Guiso, N.3
  • 31
    • 0024386073 scopus 로고
    • Isolation and characterisation of the C-terminal signal directing export of E. Coli hemolysin across both bacterial membranes
    • Koronakis, V., Koronakis, E., and Hughes, C. (1989) Isolation and characterisation of the C-terminal signal directing export of E. Coli hemolysin across both bacterial membranes. EMBO J 8: 595-605.
    • (1989) EMBO J , vol.8 , pp. 595-605
    • Koronakis, V.1    Koronakis, E.2    Hughes, C.3
  • 32
    • 0032586774 scopus 로고    scopus 로고
    • Bordetella pertussis adenylate cyclase: A toxin with multiple talents
    • Ladant, D., and Ullmann, A. (1999) Bordetella pertussis adenylate cyclase: a toxin with multiple talents. Trends Microbiol 7: 172-176.
    • (1999) Trends Microbiol , vol.7 , pp. 172-176
    • Ladant, D.1    Ullmann, A.2
  • 33
    • 0002846942 scopus 로고    scopus 로고
    • The family of the multigenic encoded RTX toxins
    • Alouf, J.E., Freer, J.H. (eds). London: Academic Press
    • Ludwig, A., and Goebel, W. (1999) The family of the multigenic encoded RTX toxins. In The Comprehensive Sourcebook of Bacterial Protein Toxins. Alouf, J.E., Freer, J.H. (eds). London: Academic Press, pp. 330-348.
    • (1999) The Comprehensive Sourcebook of Bacterial Protein Toxins , pp. 330-348
    • Ludwig, A.1    Goebel, W.2
  • 34
    • 0010505665 scopus 로고    scopus 로고
    • Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica
    • Martinez, D.T.G., Miller, J.F., and Cotter, P.A. (1996) Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica. Mol Microbiol 22: 895-908.
    • (1996) Mol Microbiol , vol.22 , pp. 895-908
    • Martinez, D.T.G.1    Miller, J.F.2    Cotter, P.A.3
  • 35
    • 0025047753 scopus 로고
    • Bordetella pertussis adenylate cyclase toxin: Intoxication of host cells by bacterial invasion
    • Mouallem, M., Farfel, Z., and Hanski, E. (1990) Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion. Infect Immun 58: 3759-3764.
    • (1990) Infect Immun , vol.58 , pp. 3759-3764
    • Mouallem, M.1    Farfel, Z.2    Hanski, E.3
  • 36
    • 0023637472 scopus 로고
    • Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin
    • Pearson, R.D., Symes, P., Conboy, M., Weiss, A.A., and Hewlett, E.L. (1987) Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin. J Immunol 139: 2749-2754.
    • (1987) J Immunol , vol.139 , pp. 2749-2754
    • Pearson, R.D.1    Symes, P.2    Conboy, M.3    Weiss, A.A.4    Hewlett, E.L.5
  • 37
    • 0025891562 scopus 로고
    • Adenylate cyclase toxin from Bordetella pertussis. The relationship between induction of cAMP and hemolysis
    • Rogel, A., Meller, R., and Hanski, E. (1991) Adenylate cyclase toxin from Bordetella pertussis. The relationship between induction of cAMP and hemolysis. J Biol Chem 266: 3154-3161.
    • (1991) J Biol Chem , vol.266 , pp. 3154-3161
    • Rogel, A.1    Meller, R.2    Hanski, E.3
  • 38
    • 0024449602 scopus 로고
    • Bordetella pertussis adenylate cyclase: Purification and characterization of the toxic form of the enzyme
    • Rogel, A., Schultz, J.E., Brownlie, R.M., Coote, J.G., Parton, R., and Hanski, E. (1989) Bordetella pertussis adenylate cyclase: purification and characterization of the toxic form of the enzyme. EMBO J 8: 2755-2760.
    • (1989) EMBO J , vol.8 , pp. 2755-2760
    • Rogel, A.1    Schultz, J.E.2    Brownlie, R.M.3    Coote, J.G.4    Parton, R.5    Hanski, E.6
  • 39
    • 0028877021 scopus 로고
    • Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. Characterization of multiple calcium-binding sites and calcium-induced conformational changes
    • Rose, T., Sebo, P., Bellalou, J., and Ladant, D. (1995) Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. Characterization of multiple calcium-binding sites and calcium-induced conformational changes. J Biol Chem 270: 26370-26376.
    • (1995) J Biol Chem , vol.270 , pp. 26370-26376
    • Rose, T.1    Sebo, P.2    Bellalou, J.3    Ladant, D.4
  • 40
    • 0026645587 scopus 로고
    • Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities
    • Sakamoto, H., Bellalou, J., Sebo, P., and Ladant, D. (1992) Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities. J Biol Chem 267: 13598-13602.
    • (1992) J Biol Chem , vol.267 , pp. 13598-13602
    • Sakamoto, H.1    Bellalou, J.2    Sebo, P.3    Ladant, D.4
  • 41
    • 0016374975 scopus 로고
    • A highly sensitive adenylate cyclase assay
    • Salomon, Y., Londos, C., and Rodbell, M. (1974) A highly sensitive adenylate cyclase assay. Anal Biochem 58:541-548.
    • (1974) Anal Biochem , vol.58 , pp. 541-548
    • Salomon, Y.1    Londos, C.2    Rodbell, M.3
  • 42
    • 0034443266 scopus 로고    scopus 로고
    • Phagosome acidification has opposite effects on intracellular survival of Bordetella pertussis and B. bronchiseptica
    • Schneider, B., Gross, R., and Haas, A. (2000) Phagosome acidification has opposite effects on intracellular survival of Bordetella pertussis and B. bronchiseptica. Infect Immun 68: 7039-7048.
    • (2000) Infect Immun , vol.68 , pp. 7039-7048
    • Schneider, B.1    Gross, R.2    Haas, A.3
  • 43
    • 0025879152 scopus 로고
    • High-level synthesis of active adenylate cyclase toxin of Bordetella pertussis in a reconstructed Escherichia coli system
    • Sebo, P., Glaser, P., Sakamoto, H., and Ullmann, A. (1991) High-level synthesis of active adenylate cyclase toxin of Bordetella pertussis in a reconstructed Escherichia coli system. Gene 104: 19-24.
    • (1991) Gene , vol.104 , pp. 19-24
    • Sebo, P.1    Glaser, P.2    Sakamoto, H.3    Ullmann, A.4
  • 44
    • 0027219645 scopus 로고
    • Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy-proximal secretion signals by the Escherichia coli alpha-haemolysin translocator
    • Sebo, P., and Ladant, D. (1993) Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy-proximal secretion signals by the Escherichia coli alpha-haemolysin translocator. Mol Microbiol 9: 999-1009.
    • (1993) Mol Microbiol , vol.9 , pp. 999-1009
    • Sebo, P.1    Ladant, D.2
  • 45
    • 0018216671 scopus 로고
    • Polymorphonuclear leukocyte-inhibitory factor of Bordetella pertussis. I. Extraction and partial purification of phagocytosis- and chemotaxis-inhibitory activities
    • Utsumi, S., Sonoda, S., Imagawa, T., and Kanoh, M. (1978) Polymorphonuclear leukocyte-inhibitory factor of Bordetella pertussis. I. Extraction and partial purification of phagocytosis- and chemotaxis-inhibitory activities. Biken J 21: 121-135.
    • (1978) Biken J , vol.21 , pp. 121-135
    • Utsumi, S.1    Sonoda, S.2    Imagawa, T.3    Kanoh, M.4
  • 46
    • 0034444555 scopus 로고    scopus 로고
    • Neutralizing antibodies to adenylate cyclase toxin promote phagocytosis of Bordetella pertussis by human neutrophils
    • Weingart, C.L., Mobberley-Schuman, P.S., Hewlett, E.L., Gray, M.C., and Weiss, A.A. (2000) Neutralizing antibodies to adenylate cyclase toxin promote phagocytosis of Bordetella pertussis by human neutrophils. Infect Immun 68: 7152-7155.
    • (2000) Infect Immun , vol.68 , pp. 7152-7155
    • Weingart, C.L.1    Mobberley-Schuman, P.S.2    Hewlett, E.L.3    Gray, M.C.4    Weiss, A.A.5
  • 47
    • 0020524316 scopus 로고
    • Tn5-induced mutations affecting virulence factors of Bordetella pertussis
    • Weiss, A.A., Hewlett, E.L., Myers, G.A., and Falkow, S. (1983) Tn5-induced mutations affecting virulence factors of Bordetella pertussis. Infect Immun 42: 33-41.
    • (1983) Infect Immun , vol.42 , pp. 33-41
    • Weiss, A.A.1    Hewlett, E.L.2    Myers, G.A.3    Falkow, S.4
  • 48
    • 0026080402 scopus 로고
    • Pore-forming cytolysins of Gram-negative bacteria
    • Welch, R.A. (1991) Pore-forming cytolysins of Gram-negative bacteria. Mol Microbiol 5: 521-528.
    • (1991) Mol Microbiol , vol.5 , pp. 521-528
    • Welch, R.A.1
  • 49
    • 0034467679 scopus 로고    scopus 로고
    • RTX toxin structure and function: A story of numerous anomalies and few analogies in toxin biology
    • Welch, R.A. (2001) RTX toxin structure and function: a story of numerous anomalies and few analogies in toxin biology. Curr Topics Microbiol Immunol 257: 85-111.
    • (2001) Curr Topics Microbiol Immunol , vol.257 , pp. 85-111
    • Welch, R.A.1
  • 50
    • 0024321787 scopus 로고
    • Detection of Bordetella pertussis by determination of adenylate cyclase activity
    • Wirsing, V.K.H., Tacken, A., and Hewlett, E.L. (1989) Detection of Bordetella pertussis by determination of adenylate cyclase activity. Eur J Clin Microbiol Infect Dis 8: 633-636.
    • (1989) Eur J Clin Microbiol Infect Dis , vol.8 , pp. 633-636
    • Wirsing, V.K.H.1    Tacken, A.2    Hewlett, E.L.3
  • 51
    • 0036035077 scopus 로고    scopus 로고
    • Mechanism of association of adenylate cyclase toxin with the surface of Bordetella pertussis: A role for toxin-filamentous haemagglutinin interaction
    • Zaretzky, F.R., Gray, M.C., and Hewlett, E.L. (2002) Mechanism of association of adenylate cyclase toxin with the surface of Bordetella pertussis: a role for toxin-filamentous haemagglutinin interaction. Mol Microbiol 45: 1589-1598.
    • (2002) Mol Microbiol , vol.45 , pp. 1589-1598
    • Zaretzky, F.R.1    Gray, M.C.2    Hewlett, E.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.