Engineering of protease variants exhibiting altered substrate specificity

Biochemical and Biophysical Research Communications

Volumn 371, Issue 1, 2008, Pages 122-126

  Sellamuthu, Saravanan ^a   Shin, Bae Hyun ^a   Lee, Eui Seung ^a   Rho, Seong Hwan ^a   Hwang, Wangtaek ^a   Lee, Yong Jae ^a   Han, Hye Eun ^a   Kim, Jae Il ^a   Park, Woo Jin ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Genetic assay for site specific proteolysis (GASP); HAV 3C protease; Protease engineering

Indexed keywords

PROTEINASE;

ARTICLE; ENZYME ENGINEERING; ENZYME SPECIFICITY; GENETIC SCREENING; IN VITRO STUDY; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BINDING SITES; CYSTEINE ENDOPEPTIDASES; DIRECTED MOLECULAR EVOLUTION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY; VIRAL PROTEINS; YEASTS;

HEPATITIS A VIRUS;

EID: 46349100463     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.026     Document Type: Article

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