Three-day tetrahydrobiopterin therapy increases in vivo hepatic NOS activity and reduces portal pressure in CCl4 cirrhotic rats

Journal of Hepatology

Volumn 49, Issue 2, 2008, Pages 192-197

  Matei, Vasilica ^a,b   Rodríguez Vilarrupla, Aina ^a,b   Deulofeu, Ramon ^b,c   García Calderó, Héctor ^a,b   Fernández, Mercedes ^a,b   Bosch, Jaime ^a,b   Garcia Pagán, Joan Carles ^a,b  

^a Unitat de Malalties Digestives   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

NO biodisponibility; NOS uncoupling; Portal hypertension

Indexed keywords

2,4 DIAMINO 6 HYDROXY PYRIMIDINE; CARBON TETRACHLORIDE; CYCLIC GMP; NITRIC OXIDE SYNTHASE; PYRIMIDINE; TETRAHYDROBIOPTERIN;

ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; HEMODYNAMICS; IN VIVO STUDY; LIVER CIRRHOSIS; MALE; NONHUMAN; PORTAL HYPERTENSION; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT;

ANIMALS; BIOPTERIN; CARBON TETRACHLORIDE; CYCLIC GMP; ENZYME INHIBITORS; HYPERTENSION, PORTAL; HYPOXANTHINES; LIVER; LIVER CIRRHOSIS; MALE; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; SPLANCHNIC CIRCULATION;

EID: 46349096789     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.04.014     Document Type: Article

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