Mechanistic insights into ventricular arrhythmias from mapping studies in humans

Heart Rhythm

Volumn 5, Issue 6 SUPPL., 2008, Pages

  Attin, Mina ^a   Ideker, Raymond E ^a   Pogwizd, Steven M ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Cardiac mapping; Nonreentrant mechanism; Ventricular fibrillation; Ventricular tachycardia

Indexed keywords

ACTION POTENTIAL; ARTICLE; CONGESTIVE CARDIOMYOPATHY; DEFIBRILLATOR; DISEASE MODEL; ELECTROCARDIOGRAPHY; ELECTRODE; ENDOCARDIUM; EPICARDIUM; HEART CONDUCTION; HEART INFARCTION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; INTRAOPERATIVE PERIOD; ISCHEMIC HEART DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SUDDEN DEATH;

CARDIOMYOPATHY, DILATED; CHRONIC DISEASE; ELECTROPHYSIOLOGICAL PHENOMENA; HEART; HUMANS; MYOCARDIAL ISCHEMIA; TACHYCARDIA, VENTRICULAR;

EID: 46349095755     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2008.03.028     Document Type: Article

References (29)

1. J. Kjekshus Arrhythmias and mortality in congestive heart failure Am J Cardiol 65 1990 42I 48I
2. R. Lazzara B.J. Scherlag Mechanisms of monomorphic ventricular tachycardia in coronary artery disease J Interv Card Electrophysiol 8 2003 87 92
3. M.E. Josephson Electrophysiology of ventricular tachycardia: an historical perspective J Cardiovasc Electrophysiol 14 2003 1134 1148
4. L. Harris E. Downar L. Mickleborough Activation sequence of ventricular tachycardia: endocardial and epicardial mapping studies in the human ventricle J Am Coll Cardiol 10 1987 1040 1047
5. E. Downar S. Kimber L. Harris Endocardial mapping of ventricular tachycardia in the intact human heart II. Evidence for multiuse reentry in a functional sheet of surviving myocardium J Am Coll Cardiol 20 1992 869 878
6. J.M. de Bakker F.J. van Capelle M.J. Janse Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation Circulation 77 1988 589 606
7. S.M. Pogwizd R.H. Hoyt J.E. Saffitz Reentrant and focal mechanisms underlying ventricular tachycardia in the human heart Circulation 86 1992 1872 1887
8. S.M. Pogwizd M.K. Chung M.E. Cain Termination of ventricular tachycardia in the human heart Insights from three-dimensional mapping of nonsustained and sustained ventricular tachycardias Circulation 95 1997 2528 2540
9. M.K. Chung S.M. Pogwizd D.P. Miller Three-dimensional mapping of the initiation of nonsustained ventricular tachycardia in the human heart Circulation 95 1997 2517 2527
10. H.H. Hsia F.E. Marchlinski Electrophysiology studies in patients with dilated cardiomyopathies Card Electrophysiol Rev 6 2002 472 481
11. K.P. Anderson R. Walker P. Urie Myocardial electrical propagation in patients with idiopathic dilated cardiomyopathy J Clin Invest 92 1993 122 140
12. S.M. Pogwizd J.P. McKenzie M.E. Cain Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy Circulation 98 1998 2404 2414
13. S.M. Pogwizd K. Schlotthauer L. Li Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness Circ Res 88 2001 1159 1167
14. A.L. Wit M.R. Rosen Afterdepolarizations and triggered activity: distinction from automaticity as an arrhythmogenic mechanism H.A. Fozzard E. Habert R.B., et al. Jennings The Heart and Cardiovascular System: Scientific Foundations 2d ed. 1992 Raven Press New York 2113 2163
15. S.M. Pogwizd D.M. Bers Cellular basis of triggered arrhythmias in heart failure Trends Cardiovasc Med 14 2004 61 66
16. M.W. Veldkamp A.O. Verkerk A.C. van Ginneken Norepinephrine induces action potential prolongation and early afterdepolarizations in ventricular myocytes isolated from human end-stage failing hearts Eur Heart J 22 2001 955 963
17. J.T. Vermeulen M.A. McGuire T. Opthof Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts Cardiovasc Res 28 1994 1547 1554
18. G.F. Tomaselli D.J. Beuckelmann H.G. Calkins Sudden cardiac death in heart failure The role of abnormal repolarization Circulation 90 1994 2534 2539
19. X. Ai S.M. Pogwizd Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A Circ Res 96 2005 54 63
20. F.G. Akar D.D. Spragg R.S. Tunin Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy Circ Res 95 2004 717 725
21. J.N. Weiss Factors determining the transition from ventricular tachycardia to ventricular fibrillation Heart Rhythm 2 2005 1008 1010
22. J. Jalife O. Berenfeld Molecular mechanisms and global dynamics of fibrillation: an integrative approach to the underlying basis of vortex-like reentry J Theor Biol 230 2004 475 487
23. T.J. Wu J.J. Ong C. Hwang Characteristics of wave fronts during ventricular fibrillation in human hearts with dilated cardiomyopathy: role of increased fibrosis in the generation of reentry J Am Coll Cardiol 32 1998 187 196
24. K. Nanthakumar G.P. Walcott S. Melnick Epicardial organization of human ventricular fibrillation Heart Rhythm 1 2004 14 23
25. S. Masse E. Downar V. Chauhan Ventricular fibrillation in myopathic human hearts: mechanistic insights from in vivo global endocardial and epicardial mapping Am J Physiol Heart Circ Physiol 292 2007 H2589 H2597
26. M.P. Nash A. Mourad R.H. Clayton Evidence for multiple mechanisms in human ventricular fibrillation Circulation 114 2006 536 542
27. K. Nanthakumar J. Jalife S. Masse Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans Am J Physiol Heart Circ Physiol 293 2007 H875 H880
28. D.A. Cesario M. Vaseghi N.G. Boyle Value of high-density endocardial and epicardial mapping for catheter ablation of hemodynamically unstable ventricular tachycardia Heart Rhythm 3 2006 1 10
29. M. Haissaguerre M. Shoda P. Jais Mapping and ablation of idiopathic ventricular fibrillation Circulation 106 2002 962 967