Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives

BMC Pharmacology

Volumn 8, Issue , 2008, Pages

  Volvert, Marie Laure ^a   Seyen, Sandrine ^a   Piette, Marie ^a   Evrard, Brigitte ^a   Gangolf, Marjorie ^a   Plumier, Jean Christophe ^a   Bettendorff, Lucien ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALKALINE PHOSPHATASE; BENFOTIAMINE; CELL PROTEIN; FURSULTIAMINE; LIPID; OIL; ORGANIC SOLVENT; SULBUTIAMINE; THIAMINE; THIAMINE ALLYL DISULFIDE; THIAMINE DERIVATIVE; THIAMINE DISULFIDE; THIAMINE DISULFIDE DERIVATIVE; THIAMINE PHOSPHATE; WATER; BENPHOTHIAMINE; DRUG DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG LIVER LEVEL; DRUG MECHANISM; DRUG PENETRATION; DRUG STRUCTURE; LIPID SOLUBILITY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PROTEIN CONTENT; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; DRUG EFFECT; MALE; METABOLISM; SOLUBILITY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; LIPIDS; MALE; MICE; MICE, INBRED C57BL; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAMINE;

EID: 46349088796     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-8-10     Document Type: Article

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