Paroxetine hydrochloride controlled release POLYOX® matrix tablets: Screening of formulation variables using Plackett-Burman screening design

Archives of Pharmacal Research

Volumn 31, Issue 3, 2008, Pages 399-405

  Jin, Shun Ji ^a   Yoo, Yeon Hee ^a   Kim, Min Soo ^a   Kim, Jeong Soo ^a   Park, Jeong Sook ^a   Hwang, Sung Joo ^a  

^a Chungnam National University   (South Korea)

Author keywords

Controlled release; Paroxetine hydrochloride; Plackett Burman screening design; POLYOX

Indexed keywords

ANTIDEPRESSANT AGENT; CELLULOSE; CITRIC ACID; DRUG CARRIER; DRUG DERIVATIVE; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL DERIVATIVE; METHYLCELLULOSE; METHYLMETHACRYLATE METHACRYLIC ACID COPOLYMER; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; PAROXETINE; POLYMETHACRYLIC ACID DERIVATIVE; SEROTONIN UPTAKE INHIBITOR;

ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG FORMULATION; HARDNESS; KINETICS; METHODOLOGY; MOLECULAR WEIGHT; PHARMACEUTICS; SOLUBILITY; STATISTICAL MODEL; TABLET;

ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CITRIC ACID; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; HARDNESS; KINETICS; METHYLCELLULOSE; MODELS, STATISTICAL; MOLECULAR WEIGHT; PAROXETINE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; SEROTONIN UPTAKE INHIBITORS; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 46249132896     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-1170-0     Document Type: Article

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