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Volumn 52, Issue 7, 2008, Pages 2420-2427

Establishment of a cell-based assay for screening of compounds inhibiting very early events in the cytomegalovirus replication cycle and characterization of a compound identified using the assay

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,5 DICHLORO 4 PYRIDYL)PIPERIDINE 4 CARBOXAMIDE; ANTIVIRUS AGENT; DERMATAN SULFATE; GANCICLOVIR; HEPARAN SULFATE; IMMEDIATE EARLY PROTEIN; LUCIFERASE; MESSENGER RNA; ROSCOVITINE; SURAMIN; VIRUS DNA;

EID: 46249110369     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00134-08     Document Type: Article
Times cited : (22)

References (48)
  • 2
    • 0027502677 scopus 로고
    • Selective inhibition of human cytomegalovirus replication by naphthalenedisulfonic acid derivatives
    • Baba, M., K. Konno, S. Shigeta, A. Wickramasinghe, and P. Mohan. 1993. Selective inhibition of human cytomegalovirus replication by naphthalenedisulfonic acid derivatives. Antiviral Res. 20:223-233.
    • (1993) Antiviral Res , vol.20 , pp. 223-233
    • Baba, M.1    Konno, K.2    Shigeta, S.3    Wickramasinghe, A.4    Mohan, P.5
  • 4
    • 0036149161 scopus 로고    scopus 로고
    • Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression
    • Bechtel, J. T., and T. Shenk. 2002. Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression. J. Virol. 76:1043-1050.
    • (2002) J. Virol , vol.76 , pp. 1043-1050
    • Bechtel, J.T.1    Shenk, T.2
  • 5
    • 0033083487 scopus 로고    scopus 로고
    • A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors
    • Bedard, J., S. May, D. Barbeau, L. Yuen, R. F. Rando, and T. L. Bowlin. 1999. A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors. Antivir. Res. 41:35-43.
    • (1999) Antivir. Res , vol.41 , pp. 35-43
    • Bedard, J.1    May, S.2    Barbeau, D.3    Yuen, L.4    Rando, R.F.5    Bowlin, T.L.6
  • 6
    • 33747141729 scopus 로고    scopus 로고
    • Antiviral drugs for cytomegalovirus diseases
    • Biron, K. K. 2006. Antiviral drugs for cytomegalovirus diseases. Antivir. Res. 71:154-163.
    • (2006) Antivir. Res , vol.71 , pp. 154-163
    • Biron, K.K.1
  • 7
    • 0036956494 scopus 로고    scopus 로고
    • Development of a green fluorescent protein reporter cell line to reduce biohazards associated with detection of infectious Cercopithecine herpesvirus 1 (monkey B virus) in clinical specimens
    • Black, D. H., J. T. Saliki, and R. Eberle. 2002. Development of a green fluorescent protein reporter cell line to reduce biohazards associated with detection of infectious Cercopithecine herpesvirus 1 (monkey B virus) in clinical specimens. Comp. Med. 52:534-542.
    • (2002) Comp. Med , vol.52 , pp. 534-542
    • Black, D.H.1    Saliki, J.T.2    Eberle, R.3
  • 10
    • 0033988505 scopus 로고    scopus 로고
    • A nine-codon deletion mutation in the cytomegalovirus UL97 phosphotransferase gene confers resistance to ganciclovir
    • Chou, S., and C. L. Meichsner. 2000. A nine-codon deletion mutation in the cytomegalovirus UL97 phosphotransferase gene confers resistance to ganciclovir. Antimicrob. Agents Chemother. 44:183-185.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 183-185
    • Chou, S.1    Meichsner, C.L.2
  • 11
    • 0037764114 scopus 로고    scopus 로고
    • New inhibitors of human cytomegalovirus (HCMV) on the horizon
    • De Clercq, E. 2003. New inhibitors of human cytomegalovirus (HCMV) on the horizon. J. Antimicrob. Chemother. 51:1079-1083.
    • (2003) J. Antimicrob. Chemother , vol.51 , pp. 1079-1083
    • De Clercq, E.1
  • 12
    • 33748659012 scopus 로고    scopus 로고
    • Human cytomegalovirus pUS24 is a virion protein that functions very early in the replication cycle
    • Feng, X., J. Schröer, D. Yu, and T. Shenk. 2006. Human cytomegalovirus pUS24 is a virion protein that functions very early in the replication cycle. J. Virol. 80:8371-8378.
    • (2006) J. Virol , vol.80 , pp. 8371-8378
    • Feng, X.1    Schröer, J.2    Yu, D.3    Shenk, T.4
  • 13
    • 28844452427 scopus 로고    scopus 로고
    • New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure
    • Gilbert, C., and G. Boivin. 2005. New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure. Antimicrob. Agents Chemother. 49:4860-4866.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 4860-4866
    • Gilbert, C.1    Boivin, G.2
  • 14
    • 0017884939 scopus 로고
    • Varicella-zoster virus: Isolation and propagation in human melanoma cells at 36 and 32 degrees C
    • Grose, C., and P. A. Brunel. 1978. Varicella-zoster virus: isolation and propagation in human melanoma cells at 36 and 32 degrees C. Infect. Immun. 19:199-203.
    • (1978) Infect. Immun , vol.19 , pp. 199-203
    • Grose, C.1    Brunel, P.A.2
  • 15
    • 0023851532 scopus 로고
    • Further studies on the mechanism of centrifugal enhancement of cytomegalovirus infectivity
    • Hudson, J. B. 1988. Further studies on the mechanism of centrifugal enhancement of cytomegalovirus infectivity. J. Virol. Methods 19:97-108.
    • (1988) J. Virol. Methods , vol.19 , pp. 97-108
    • Hudson, J.B.1
  • 16
    • 0028228746 scopus 로고
    • Alphaherpesvirus origin-binding protein homolog encoded by human herpesvirus 6B, a betaherpesvirus, binds to nucleotide sequences that are similar to ori regions of alphaherpesviruses
    • Inoue, N., T. R. Dambaugh, J. C. Rapp, and P. E. Pellett. 1994. Alphaherpesvirus origin-binding protein homolog encoded by human herpesvirus 6B, a betaherpesvirus, binds to nucleotide sequences that are similar to ori regions of alphaherpesviruses. J. Virol. 68:4126-4136.
    • (1994) J. Virol , vol.68 , pp. 4126-4136
    • Inoue, N.1    Dambaugh, T.R.2    Rapp, J.C.3    Pellett, P.E.4
  • 17
    • 0038758763 scopus 로고    scopus 로고
    • Characterization of entry mechanisms of human herpesvirus 8 by using an Rta-dependent reporter cell line
    • Inoue, N., J. Winter, R. B. Lal, M. K. Offermann, and S. Koyano. 2003. Characterization of entry mechanisms of human herpesvirus 8 by using an Rta-dependent reporter cell line. J. Virol. 77:8147-8152.
    • (2003) J. Virol , vol.77 , pp. 8147-8152
    • Inoue, N.1    Winter, J.2    Lal, R.B.3    Offermann, M.K.4    Koyano, S.5
  • 18
    • 0346294229 scopus 로고    scopus 로고
    • Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule
    • Jones, T. R., S. W. Lee, S. V. Johann, V. Razinkov, R. J. Visalli, B. Feld, J. D. Bloom, and J. O'Connell. 2004. Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule. J. Virol. 78:1289-1300.
    • (2004) J. Virol , vol.78 , pp. 1289-1300
    • Jones, T.R.1    Lee, S.W.2    Johann, S.V.3    Razinkov, V.4    Visalli, R.J.5    Feld, B.6    Bloom, J.D.7    O'Connell, J.8
  • 19
    • 0032849072 scopus 로고    scopus 로고
    • Transactivation of herpes simplex virus type 1 immediate-early gene expression by virion-associated factors is blocked by an inhibitor of cyclin-dependent protein kinases
    • Jordan, R., L. Schang, and P. A. Schaffer. 1999. Transactivation of herpes simplex virus type 1 immediate-early gene expression by virion-associated factors is blocked by an inhibitor of cyclin-dependent protein kinases. J. Virol. 73:8843-8847.
    • (1999) J. Virol , vol.73 , pp. 8843-8847
    • Jordan, R.1    Schang, L.2    Schaffer, P.A.3
  • 22
    • 0026562720 scopus 로고
    • Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
    • Kimpton, J., and M. Emerman. 1992. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66:2232-2239.
    • (1992) J. Virol , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 23
    • 0024459235 scopus 로고
    • Sequences in the human cytomegalovirus 2.7-kilobase RNA promoter which mediate its regulation as an early gene
    • Klucher, K. M., D. K. Rabert, and D. H. Spector. 1989. Sequences in the human cytomegalovirus 2.7-kilobase RNA promoter which mediate its regulation as an early gene. J. Virol. 63:5334-5343.
    • (1989) J. Virol , vol.63 , pp. 5334-5343
    • Klucher, K.M.1    Rabert, D.K.2    Spector, D.H.3
  • 24
    • 0037977766 scopus 로고    scopus 로고
    • Glycoproteins M and N of human herpesvirus 8 form a complex and inhibit cell fusion
    • Koyano, S., E. C. Mar, F. R. Stamey, and N. Inoue. 2003. Glycoproteins M and N of human herpesvirus 8 form a complex and inhibit cell fusion. J. Gen. Virol. 84:1485-1491.
    • (2003) J. Gen. Virol , vol.84 , pp. 1485-1491
    • Koyano, S.1    Mar, E.C.2    Stamey, F.R.3    Inoue, N.4
  • 25
    • 3242713054 scopus 로고    scopus 로고
    • Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid
    • Krug, L. T., V. P. Pozharskaya, Y. Yu, N. Inoue, and M. K. Offermann. 2004. Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid. J. Virol. 78:8359-8371.
    • (2004) J. Virol , vol.78 , pp. 8359-8371
    • Krug, L.T.1    Pozharskaya, V.P.2    Yu, Y.3    Inoue, N.4    Offermann, M.K.5
  • 26
    • 23044503350 scopus 로고    scopus 로고
    • Inhibition of protein kinases C prevents murine cytomegalovirus replication
    • Kucić, N., H. Mahmutefendić, and P. Lucin. 2005. Inhibition of protein kinases C prevents murine cytomegalovirus replication. J. Gen. Virol. 86:2153-2161.
    • (2005) J. Gen. Virol , vol.86 , pp. 2153-2161
    • Kucić, N.1    Mahmutefendić, H.2    Lucin, P.3
  • 27
    • 0034036546 scopus 로고    scopus 로고
    • Recombinant green fluorescent protein-expressing human cytomegalovirus as a tool for screening antiviral agents
    • Marschall, M., M. Freitag, S. Weiler, G. Sorg, and T. Stamminger. 2000. Recombinant green fluorescent protein-expressing human cytomegalovirus as a tool for screening antiviral agents. Antimicrob. Agents Chemother. 44:1588-1597.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 1588-1597
    • Marschall, M.1    Freitag, M.2    Weiler, S.3    Sorg, G.4    Stamminger, T.5
  • 28
    • 0034428359 scopus 로고    scopus 로고
    • Analysis of virus-infected cells by flow cytometry
    • McSharry, J. J. 2000. Analysis of virus-infected cells by flow cytometry. Methods 21:249-257.
    • (2000) Methods , vol.21 , pp. 249-257
    • McSharry, J.J.1
  • 29
    • 0001593941 scopus 로고    scopus 로고
    • Cytomegaloviruses and their replication
    • D. M. Knipe and P. M. Howley ed, Lippincott Williams & Wilkins, Philadelphia, PA
    • Mocarski, E. S., and C. T. Courcelle. 2001. Cytomegaloviruses and their replication, p. 2629-2673. In D. M. Knipe and P. M. Howley (ed.), Fields virology. Lippincott Williams & Wilkins, Philadelphia, PA.
    • (2001) Fields virology , pp. 2629-2673
    • Mocarski, E.S.1    Courcelle, C.T.2
  • 30
    • 33645241644 scopus 로고    scopus 로고
    • UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells
    • Munger, J., D. Yu, and T. Shenk. 2006. UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells. J. Virol. 80:3541-3548.
    • (2006) J. Virol , vol.80 , pp. 3541-3548
    • Munger, J.1    Yu, D.2    Shenk, T.3
  • 31
    • 34247189159 scopus 로고    scopus 로고
    • Real-time PCR assay using specimens on filter disks as a template for detection of cytomegalovirus in urine
    • Nozawa, N., S. Koyano, Y. Yamamoto, Y. Inami, I. Kurane, and N. Inoue. 2007. Real-time PCR assay using specimens on filter disks as a template for detection of cytomegalovirus in urine. J. Clin. Microbiol. 45:1305-1307.
    • (2007) J. Clin. Microbiol , vol.45 , pp. 1305-1307
    • Nozawa, N.1    Koyano, S.2    Yamamoto, Y.3    Inami, Y.4    Kurane, I.5    Inoue, N.6
  • 32
    • 33847662463 scopus 로고    scopus 로고
    • Etiology of severe sensorineural hearing loss in children: Independent impact of congenital cytomegalovirus infection and GJB2 mutations
    • Ogawa, H., T. Suzutani, Y. Baba, S. Koyano, N. Nozawa, K. Ishibashi, K. Fujieda, N. Inoue, and K. Omori. 2007. Etiology of severe sensorineural hearing loss in children: independent impact of congenital cytomegalovirus infection and GJB2 mutations. J. Infect. Dis. 195:782-788.
    • (2007) J. Infect. Dis , vol.195 , pp. 782-788
    • Ogawa, H.1    Suzutani, T.2    Baba, Y.3    Koyano, S.4    Nozawa, N.5    Ishibashi, K.6    Fujieda, K.7    Inoue, N.8    Omori, K.9
  • 34
    • 0030038093 scopus 로고    scopus 로고
    • Transgenic cell lines for detection of animal viruses
    • Olivo, P. D. 1996. Transgenic cell lines for detection of animal viruses. Clin. Microbiol. Rev. 9:321-334.
    • (1996) Clin. Microbiol. Rev , vol.9 , pp. 321-334
    • Olivo, P.D.1
  • 35
    • 0000974298 scopus 로고    scopus 로고
    • Cytomegalovirus
    • D. M. Knipe and P. M. Howley ed, Lippincott Williams & Wilkins, Philadelphia, PA
    • Pass, R. F. 2001. Cytomegalovirus, p. 2675-2705. In D. M. Knipe and P. M. Howley (ed.), Fields virology. Lippincott Williams & Wilkins, Philadelphia, PA.
    • (2001) Fields virology , pp. 2675-2705
    • Pass, R.F.1
  • 36
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8392-8396.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 37
    • 0034037288 scopus 로고    scopus 로고
    • In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections
    • Rybak, R. J., C. B. Hartline, Y. L. Qiu, J. Zemlicka, E. Harden, G. Marshall, J. P. Sommadossi, and E. R. Kern. 2000. In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections. Antimicrob. Agents Chemother. 44:1506-1511.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 1506-1511
    • Rybak, R.J.1    Hartline, C.B.2    Qiu, Y.L.3    Zemlicka, J.4    Harden, E.5    Marshall, G.6    Sommadossi, J.P.7    Kern, E.R.8
  • 38
    • 4644319639 scopus 로고    scopus 로고
    • Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production
    • Sanchez, V., A. K. McElroy, J. Yen, S. Tamrakar, C. L. Clark, R. A. Schwartz, and D. H. Spector. 2004. Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production. J. Virol. 78:11219-11232.
    • (2004) J. Virol , vol.78 , pp. 11219-11232
    • Sanchez, V.1    McElroy, A.K.2    Yen, J.3    Tamrakar, S.4    Clark, C.L.5    Schwartz, R.A.6    Spector, D.H.7
  • 39
    • 0035991784 scopus 로고    scopus 로고
    • Evaluation of antiviral activity of different origin compounds by flow cytometry
    • Siennicka, J., A. Trzcińska, and M. Kańtoch. 2002. Evaluation of antiviral activity of different origin compounds by flow cytometry. Acta Microbiol. Pol. 51:79-83.
    • (2002) Acta Microbiol. Pol , vol.51 , pp. 79-83
    • Siennicka, J.1    Trzcińska, A.2    Kańtoch, M.3
  • 40
    • 0030896925 scopus 로고    scopus 로고
    • Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus
    • Sodeik, B., M. W. Ebersold, and A. Helenius. 1997. Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J. Cell Biol. 136:1007-1021.
    • (1997) J. Cell Biol , vol.136 , pp. 1007-1021
    • Sodeik, B.1    Ebersold, M.W.2    Helenius, A.3
  • 41
    • 0023425999 scopus 로고
    • Insertion and deletion mutagenesis of the human cytomegalovirus genome
    • Spaete, R. R., and E. S. Mocarski. 1987. Insertion and deletion mutagenesis of the human cytomegalovirus genome. Proc. Natl. Acad. Sci. USA 84:7213-7217.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7213-7217
    • Spaete, R.R.1    Mocarski, E.S.2
  • 44
    • 1542377590 scopus 로고    scopus 로고
    • Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus
    • Taylor, S. L., P. R. Kinchington, A. Brooks, and J. F. Moffat. 2004. Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus. J. Virol. 78:2853-2862.
    • (2004) J. Virol , vol.78 , pp. 2853-2862
    • Taylor, S.L.1    Kinchington, P.R.2    Brooks, A.3    Moffat, J.F.4
  • 45
    • 33746881454 scopus 로고    scopus 로고
    • Novel real-time monitoring system for human cytomegalovirus-infected cells in vitro that uses a green fluorescent protein-PML-expressing cell line
    • Ueno, T., Y. Eizuru, H. Katano, T. Kurata, T. Sata, S. Irie, and K. Ogawa-Goto. 2006. Novel real-time monitoring system for human cytomegalovirus-infected cells in vitro that uses a green fluorescent protein-PML-expressing cell line. Antimicrob. Agents Chemother. 50:2806-2813.
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 2806-2813
    • Ueno, T.1    Eizuru, Y.2    Katano, H.3    Kurata, T.4    Sata, T.5    Irie, S.6    Ogawa-Goto, K.7
  • 46
    • 0042706429 scopus 로고    scopus 로고
    • DNA encapsidation as a target for anti-herpesvirus drug therapy
    • Visalli, R. J., and M. van Zeijl. 2003. DNA encapsidation as a target for anti-herpesvirus drug therapy. Antivir. Res. 59:73-87.
    • (2003) Antivir. Res , vol.59 , pp. 73-87
    • Visalli, R.J.1    van Zeijl, M.2
  • 47
    • 33748706611 scopus 로고    scopus 로고
    • Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies
    • Wang, G. Q., T. Suzutani, Y. Yamamoto, Y. Fukui, N. Nozawa, D. S. Schmid, I. Kurane, and N. Inoue. 2006. Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies. Antimicrob. Agents Chemother. 50:3142-3145.
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 3142-3145
    • Wang, G.Q.1    Suzutani, T.2    Yamamoto, Y.3    Fukui, Y.4    Nozawa, N.5    Schmid, D.S.6    Kurane, I.7    Inoue, N.8


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