Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome

Human Molecular Genetics

Volumn 17, Issue 14, 2008, Pages 2244-2254

  Napierala, Dobrawa ^a   Sam, Kathy ^a   Morello, Roy ^a   Zheng, Qiping ^a   Munivez, Elda ^a   Shivdasani, Ramesh A ^c   Lee, Brendan ^a,b  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR TRPS1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DYSPLASIA; BONE MINERALIZATION; CARTILAGE CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INTERACTION; GENE REPRESSION; GENETIC ANALYSIS; GROWTH PLATE; HETEROZYGOSITY; MOUSE; MOUSE MUTANT; NONHUMAN; PERICHONDRIUM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRICHORHINOPHALANGEAL SYNDROME;

ANIMALS; CELL DIFFERENTIATION; CHONDROCYTES; CHONDROGENESIS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FEMALE; GATA TRANSCRIPTION FACTORS; GROWTH PLATE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOCHONDRODYSPLASIAS; TRANS-ACTIVATION (GENETICS);

ERINACEIDAE; MUS;

EID: 46249102414     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn125     Document Type: Article

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