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Volumn 33, Issue 8, 2008, Pages 1475-1483

Contribution of NMDA and non-NMDA receptors to in vivo glutamate-induced calpain activation in the rat striatum. Relation to neuronal damage

Author keywords

AMPA; Calpain; Caspase 3; Kainate; Neurotoxicity; NMDA

Indexed keywords

AMPA RECEPTOR; CALCIUM; CALPAIN; CASPASE 3; FODRIN; GLUTAMIC ACID; IONOTROPIC RECEPTOR; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 46249101510     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9612-1     Document Type: Article
Times cited : (19)

References (54)
  • 1
    • 0015175326 scopus 로고
    • Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system
    • Olney JW, Ho OL, Rhee V (1971) Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Exp Brain Res 14:61-76
    • (1971) Exp Brain Res , vol.14 , pp. 61-76
    • Olney, J.W.1    Ho, O.L.2    Rhee, V.3
  • 2
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
    • Choi DW, Koh JY, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci 8:185-196
    • (1988) J Neurosci , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.Y.2    Peters, S.3
  • 3
    • 0025341925 scopus 로고
    • Non-NMDA receptor-mediated neurotoxicity in cortical culture
    • Koh JY, Goldberg MP, Hartley DM, Choi DW (1990) Non-NMDA receptor-mediated neurotoxicity in cortical culture. J Neurosci 10:693-705
    • (1990) J Neurosci , vol.10 , pp. 693-705
    • Koh, J.Y.1    Goldberg, M.P.2    Hartley, D.M.3    Choi, D.W.4
  • 4
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi DW (1987) Ionic dependence of glutamate neurotoxicity. J Neurosci 7:369-379
    • (1987) J Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 5
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall RD, Thayer SA (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J Neurosci 12:1882-1895
    • (1992) J Neurosci , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 6
    • 0025166328 scopus 로고
    • Glutamate neurotoxicity in vitro: Antagonist pharmacology and intracellular calcium concentrations
    • Michaels RL, Rothman SM (1990) Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J Neurosci 10:283-292
    • (1990) J Neurosci , vol.10 , pp. 283-292
    • Michaels, R.L.1    Rothman, S.M.2
  • 7
    • 0027380609 scopus 로고
    • Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells
    • Lafon-Cazal M, Culcasi M, Gaven F et al (1993) Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells. Neuropharmacology 32:1259-1266
    • (1993) Neuropharmacology , vol.32 , pp. 1259-1266
    • Lafon-Cazal, M.1    Culcasi, M.2    Gaven, F.3
  • 8
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and neurodegeneration
    • Mattson MP (2007) Calcium and neurodegeneration. Aging Cell 6:337-350
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 9
    • 0024850744 scopus 로고
    • The protease inhibitor leupeptin interferes with the development of LTP in hippocampal slices
    • Oliver MW, Baudry M, Lynch G (1989) The protease inhibitor leupeptin interferes with the development of LTP in hippocampal slices. Brain Res 505:233-238
    • (1989) Brain Res , vol.505 , pp. 233-238
    • Oliver, M.W.1    Baudry, M.2    Lynch, G.3
  • 10
    • 0025013459 scopus 로고
    • Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors
    • del Cerro S, Larson J, Oliver MW et al (1990) Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors. Brain Res 530:91-95
    • (1990) Brain Res , vol.530 , pp. 91-95
    • Del Cerro, S.1    Larson, J.2    Oliver, M.W.3
  • 11
    • 0025223113 scopus 로고
    • Calpain inhibitors block long-term potentiation
    • Denny JB, Polan-Curtain J, Ghuman A et al (1990) Calpain inhibitors block long-term potentiation. Brain Res 534:317-320
    • (1990) Brain Res , vol.534 , pp. 317-320
    • Denny, J.B.1    Polan-Curtain, J.2    Ghuman, A.3
  • 12
    • 0029962597 scopus 로고    scopus 로고
    • Translational suppression of calpain blocks long-term potentiation
    • Vanderklish P, Bednarski E, Lynch G (1996) Translational suppression of calpain blocks long-term potentiation. Learn Mem 3:209-217
    • (1996) Learn Mem , vol.3 , pp. 209-217
    • Vanderklish, P.1    Bednarski, E.2    Lynch, G.3
  • 13
    • 0033956278 scopus 로고    scopus 로고
    • Calpain and caspase: Can you tell the difference?
    • Wang K (2000) Calpain and caspase: can you tell the difference? Trends Neurosci 23:20-26
    • (2000) Trends Neurosci , vol.23 , pp. 20-26
    • Wang, K.1
  • 15
    • 0024347477 scopus 로고
    • Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus
    • Seubert P, Lee K, Lynch G (1989) Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus. Brain Res 492:366-370
    • (1989) Brain Res , vol.492 , pp. 366-370
    • Seubert, P.1    Lee, K.2    Lynch, G.3
  • 16
    • 0025826867 scopus 로고
    • Inhibition of proteolysis protects hippocampal neurons from ischemia
    • Lee KS, Frank S, Vanderklish P et al (1991) Inhibition of proteolysis protects hippocampal neurons from ischemia. Proc Natl Acad Sci USA 88:7233-7237
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7233-7237
    • Lee, K.S.1    Frank, S.2    Vanderklish, P.3
  • 17
    • 0027215039 scopus 로고
    • Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo
    • Rami A, Krieglstein J (1993) Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo. Brain Res 609:67-70
    • (1993) Brain Res , vol.609 , pp. 67-70
    • Rami, A.1    Krieglstein, J.2
  • 18
    • 0024020782 scopus 로고
    • Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo
    • Siman R, Noszek JC (1988) Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo. Neuron 1:279-287
    • (1988) Neuron , vol.1 , pp. 279-287
    • Siman, R.1    Noszek, J.C.2
  • 19
    • 0029045611 scopus 로고
    • Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices
    • Bahr BA, Tiriveedhi S, Park GY et al (1995) Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices. J Pharmacol Exp Ther 273:902-908
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 902-908
    • Bahr, B.A.1    Tiriveedhi, S.2    Park, G.Y.3
  • 20
    • 10644231739 scopus 로고    scopus 로고
    • Early calpain-mediated proteolysis following AMPA receptor activation compromises neuronal survival in cultured hippocampal neurons
    • Aráujo IM, Verdasca MJ, Leal EC et al (2004) Early calpain-mediated proteolysis following AMPA receptor activation compromises neuronal survival in cultured hippocampal neurons. J Neurochem 91:1322-1331
    • (2004) J Neurochem , vol.91 , pp. 1322-1331
    • Aráujo, I.M.1    Verdasca, M.J.2    Leal, E.C.3
  • 21
    • 0022479032 scopus 로고
    • NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurons
    • MacDermott AB, Mayer ML, Westbrook GL et al (1986) NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurons. Nature 321:519-522
    • (1986) Nature , vol.321 , pp. 519-522
    • MacDermott, A.B.1    Mayer, M.L.2    Westbrook, G.L.3
  • 22
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurons
    • Mayer ML, Westbrook GL (1987) Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurons. J Physiol 394:501-527
    • (1987) J Physiol , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 23
    • 0031984802 scopus 로고    scopus 로고
    • Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats
    • Markgraf CG, Velayo NL, Johnson MP et al (1998) Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats. Stroke 29:152-158
    • (1998) Stroke , vol.29 , pp. 152-158
    • Markgraf, C.G.1    Velayo, N.L.2    Johnson, M.P.3
  • 24
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M, Dypbukt JM, Bonfoco E et al (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3
  • 25
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • Bonfoco E, Krainc D, Ankarcrona M et al (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92:7162-7166
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3
  • 26
    • 0032191207 scopus 로고    scopus 로고
    • Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurons
    • Cheung NS, Pascoe CJ, Giardina SF et al (1998) Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurons. Neuropharmacology 37:1419-1429
    • (1998) Neuropharmacology , vol.37 , pp. 1419-1429
    • Cheung, N.S.1    Pascoe, C.J.2    Giardina, S.F.3
  • 27
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • Siman R, Noszek JC, Kegerise C (1989) Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J Neurosci 9:1579-1590
    • (1989) J Neurosci , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 28
    • 34249098111 scopus 로고    scopus 로고
    • Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: Relation to energy imbalance or ATP depletion?
    • Del Rio P, Montiel T, Chagoya V et al (2007) Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion? Neuroscience 146:1561-1570
    • (2007) Neuroscience , vol.146 , pp. 1561-1570
    • Del Rio, P.1    Montiel, T.2    Chagoya, V.3
  • 30
    • 1342279441 scopus 로고    scopus 로고
    • Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons
    • Massieu L, Moran J, Christen Y (2004) Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons. Brain Res 1002:76-85
    • (2004) Brain Res , vol.1002 , pp. 76-85
    • Massieu, L.1    Moran, J.2    Christen, Y.3
  • 31
    • 0029045611 scopus 로고
    • Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices
    • Bahr BA, Tiriveedhi S, Park GY et al (1995) Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices. J Pharmacol Exp Ther 273:902-908
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 902-908
    • Bahr, B.A.1    Tiriveedhi, S.2    Park, G.Y.3
  • 32
    • 0027300884 scopus 로고
    • Spectrin proteolysis in the hippocampus: A biochemical marker for neuronal injury and neuroprotection
    • Roberts-Lewis JM, Siman R (1993) Spectrin proteolysis in the hippocampus: a biochemical marker for neuronal injury and neuroprotection. Ann N Y Acad Sci 679:78-86
    • (1993) Ann N Y Acad Sci , vol.679 , pp. 78-86
    • Roberts-Lewis, J.M.1    Siman, R.2
  • 33
    • 0028282502 scopus 로고
    • Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
    • Roberts-Lewis JM, Savage MJ, Marcy VR et al (1994) Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain. J Neurosci 14:3934-3944
    • (1994) J Neurosci , vol.14 , pp. 3934-3944
    • Roberts-Lewis, J.M.1    Savage, M.J.2    Marcy, V.R.3
  • 34
    • 0037775906 scopus 로고    scopus 로고
    • Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: Implications for Huntington's disease
    • Bizat N, Hermel JM, Boyer F et al (2003) Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease. J Neurosci 23:5020-5030
    • (2003) J Neurosci , vol.23 , pp. 5020-5030
    • Bizat, N.1    Hermel, J.M.2    Boyer, F.3
  • 35
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 36
    • 0028177224 scopus 로고
    • 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline protects against both AMPA and kainate-induced lesions in the rat striatum in vivo
    • Massieu L, Tapia R (1994) 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo[f] quinoxaline protects against both AMPA and kainate-induced lesions in the rat striatum in vivo. Neuroscience 59:931-938
    • (1994) Neuroscience , vol.59 , pp. 931-938
    • Massieu, L.1    Tapia, R.2
  • 37
    • 0035980445 scopus 로고    scopus 로고
    • Neurotoxicity of glutamate uptake inhibition in vivo: Correlation with succinate dehydrogenase activity and prevention by energy substrates
    • Massieu L, Del Rio P, Montiel T (2001) Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates. Neuroscience 106:669-677
    • (2001) Neuroscience , vol.106 , pp. 669-677
    • Massieu, L.1    Del Rio, P.2    Montiel, T.3
  • 38
    • 20444371553 scopus 로고    scopus 로고
    • Differential effects of the substrate inhibitor L-trans-pyrrolidine-2,4- dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta- benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat brain in vivo
    • Montiel T, Camacho A, Estrada-Sanchez AM et al (2005) Differential effects of the substrate inhibitor L-trans-pyrrolidine-2,4-dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta-benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat brain in vivo. Neuroscience 133:667-678
    • (2005) Neuroscience , vol.133 , pp. 667-678
    • Montiel, T.1    Camacho, A.2    Estrada-Sanchez, A.M.3
  • 39
    • 33750325864 scopus 로고    scopus 로고
    • The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo
    • Camacho A, Montiel T, Massieu L (2006) The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo. Neuroscience 142:1005-1017
    • (2006) Neuroscience , vol.142 , pp. 1005-1017
    • Camacho, A.1    Montiel, T.2    Massieu, L.3
  • 40
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • Siman R, Noszek JC, Kegerise C (1989) Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J Neurosci 9:1579-1590
    • (1989) J Neurosci , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 41
    • 0029045611 scopus 로고
    • Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices
    • Bahr BA, Tiriveedhi S, Park GY et al (1995) Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices. J Pharmacol Exp Ther 273:902-908
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 902-908
    • Bahr, B.A.1    Tiriveedhi, S.2    Park, G.Y.3
  • 42
    • 9644281088 scopus 로고    scopus 로고
    • Effects of positive AMPA receptor modulators on calpain-mediated spectrin degradation in cultured hippocampal slices
    • Jourdi H, Yanagihara T, Martinez U et al (2005) Effects of positive AMPA receptor modulators on calpain-mediated spectrin degradation in cultured hippocampal slices. Neurochem Int 46:31-40
    • (2005) Neurochem Int , vol.46 , pp. 31-40
    • Jourdi, H.1    Yanagihara, T.2    Martinez, U.3
  • 43
    • 33744456765 scopus 로고    scopus 로고
    • The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures
    • Lopez-Picon FR, Kukko-Lukjanov TK, Holopainen IE (2006) The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures. Eur J Neurosci 23:2686-2694
    • (2006) Eur J Neurosci , vol.23 , pp. 2686-2694
    • Lopez-Picon, F.R.1    Kukko-Lukjanov, T.K.2    Holopainen, I.E.3
  • 44
    • 33845462397 scopus 로고    scopus 로고
    • D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo
    • Mejia-Toiber J, Montiel T, Massieu L (2006) D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. Neurochem Res 31:1399-1408
    • (2006) Neurochem Res , vol.31 , pp. 1399-1408
    • Mejia-Toiber, J.1    Montiel, T.2    Massieu, L.3
  • 45
    • 0344450761 scopus 로고    scopus 로고
    • Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired
    • Sanchez-Carbente MR, Massieu L (1999) Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired. J Neurochem 72:129-138
    • (1999) J Neurochem , vol.72 , pp. 129-138
    • Sanchez-Carbente, M.R.1    Massieu, L.2
  • 46
    • 0028940994 scopus 로고
    • Exacerbation of NMDA, AMPA and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate
    • Greene JG, Greenamyre JT (1995) Exacerbation of NMDA, AMPA and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. J Neurochem 64:2332-2338
    • (1995) J Neurochem , vol.64 , pp. 2332-2338
    • Greene, J.G.1    Greenamyre, J.T.2
  • 47
    • 0034524665 scopus 로고    scopus 로고
    • The pathogenic activation of calpain: A marker and mediator of cellular toxicity and disease states
    • Vanderklish PW, Bahr BA (2000) The pathogenic activation of calpain: a marker and mediator of cellular toxicity and disease states. Int J Exp Pathol 81:323-339
    • (2000) Int J Exp Pathol , vol.81 , pp. 323-339
    • Vanderklish, P.W.1    Bahr, B.A.2
  • 48
    • 24344501808 scopus 로고    scopus 로고
    • Spectrin and calpain: A 'target' and a 'sniper' in the pathology of neuronal cells
    • Czogalla A, Sikorski AF (2005) Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells. Cell Mol Life Sci 62:1913-1924
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1913-1924
    • Czogalla, A.1    Sikorski, A.F.2
  • 52
    • 33947533448 scopus 로고    scopus 로고
    • Calpain regulation of AMPA receptor channels in cortical piramidal neurons
    • Yuen EY, Gu Z, Yan Z (2007) Calpain regulation of AMPA receptor channels in cortical piramidal neurons. J Physiol 580:241-254
    • (2007) J Physiol , vol.580 , pp. 241-254
    • Yuen, E.Y.1    Gu, Z.2    Yan, Z.3
  • 53
    • 0032496057 scopus 로고    scopus 로고
    • Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia
    • Li P-A, Howlett W, He QP (1998) Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia. Neurosci Lett 247:17-20
    • (1998) Neurosci Lett , vol.247 , pp. 17-20
    • Li, P.-A.1    Howlett, W.2    He, Q.P.3
  • 54
    • 0031912995 scopus 로고    scopus 로고
    • Glutamate receptors in the mammalian central nervous system
    • Ozawa S, Kamiya H, Tsuzuki K (1998) Glutamate receptors in the mammalian central nervous system. Prog Neurobiol 54:581-618
    • (1998) Prog Neurobiol , vol.54 , pp. 581-618
    • Ozawa, S.1    Kamiya, H.2    Tsuzuki, K.3


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