Nonuniform sampling for global optimization of kinetic rate constants in biological pathways

Proceedings - Winter Simulation Conference

Volumn , Issue , 2006, Pages 1611-1616

  Kleinstein, Steven H ^a   Bottino, Dean ^b   Georgieva, Anna ^b   Sarangapani, Ramesh ^b   Lett, G Scott ^c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c BioAnalytics Group LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONVERGENCE OF NUMERICAL METHODS; ESTIMATION; EVOLUTIONARY ALGORITHMS; MATHEMATICAL PROGRAMMING; MINE FLOODING; MODEL STRUCTURES; OPTIMIZATION; PARAMETER ESTIMATION; RATE CONSTANTS; STEEL ANALYSIS;

(001) PARAMETER; BIOLOGICAL APPLICATIONS; BIOLOGICAL PATHWAYS; CASE STUDIES; COMMON PROBLEMS; CONVERGENCE (MATHEMATICS); DIFFERENTIAL EVOLUTION (DE); ESTIMATION PROBLEMS; EVOLUTIONARY STRATEGIES (ESS); KINETIC RATE CONSTANTS; LOCAL MINIMUMS; NON-UNIFORM SAMPLING; OPTIMIZATION ALGORITHMS; POW ERFUL TOOL;

GLOBAL OPTIMIZATION;

EID: 46149123898     PISSN: 08917736     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/WSC.2006.322934     Document Type: Conference Paper

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