Evaluation of a multiplex flow cytometric immunoassay to detect PR3- and MPO-ANCA in active and treated vasculitis, and in inflammatory bowel disease (IBD)

Journal of Immunological Methods

Volumn 336, Issue 2, 2008, Pages 104-112

  Trevisin, Michelle ^a,b   Pollock, Wendy ^b,c   Dimech, Wayne ^d   Savige, Judy ^b  

^a AUSTIN HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c GRIBBLES PATHOLOGY   (Australia)

^d National Serology Reference Laboratory   (Australia)

Author keywords

Antineutrophil cytoplasmic antibodies; Flow cytometric immunoassay; Myeloperoxidase; Proteinase 3

Indexed keywords

MYELOBLASTIN; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ACCURACY; ARTICLE; CONTROLLED STUDY; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; IMMUNOASSAY; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SMALL VESSEL VASCULITIS; VASCULITIS; WEGENER GRANULOMATOSIS;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOASSAY; INFLAMMATORY BOWEL DISEASES; MYELOBLASTIN; PEROXIDASE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; VASCULITIS;

EID: 46149123662     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2008.03.012     Document Type: Article

References (18)

1. Altman D. Diagnostic tests. In: Altman D., Machin D., Bryant T., and Martin M. (Eds). Statistics with Confidence. 2nd edition (2005), BMJ Books, London 116-118
2. Csernok E., Ahlquist D., Ullrich S., and Gross W. A critical evaluation of commercial immunoassays for antineutrophil cytoplasmic antibodies directed against proteinase 3 and myeloperoxidase in Wegener's granulomatosis and microscopic polyangiitis. Rheumatology 41 (2002) 1313
3. Csernok E., Holle J., Hellmich B., Cohen Tervaert J., Kallenberg C., Limburg P., Niles J., Pan G., Specks U., Westman K., Wieslander J., De Groot K., and Gross W. Evaluation of capture ELISA for detection of antineutrophil cytoplasmic antibodies directed against proteinase 3 in Wegener's granulomatosis: first results from a multicentre study. Rheumatology 43 (2004) 174
4. Damoiseaux J., Vaessen M., Knapen P., Van Paassen P., and Cohen Tervaert J. Evaluation of the FIDIS multiplex immunoassay for diagnosis and follow-up of ANCA-associated vasculitis (2005) (abstract)
5. Damoiseaux J., Slot M., Vaessen M., Stegeman C., Van Paassen P., and Cohen Tervaert J. Evaluation of a new fluorescent-enzyme immunoassay for diagnosis and follow-up of ANCA-associated vasculitis. J. Clin. Immunol. 25 (2005) 202
6. Falk R., and Jennette J. Antineutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N. Engl. J. Med. 318 (1988) 1651
7. Goldschmeding R., van der Schoot C., ten Bokkel Huinink D., Hack C., van den Ende M., Kallenberg C., and von dem Borne A. Wegener's granulomatosis autoantibodies identify a novel diisopropyl fluorophosphate-binding protein in the lysosomes of normal human neutrophils. J. Clin. Invest. 84 (1989) 1577
8. Kitching A., Hutchison P., Atkins R., and Holdsworth S. The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis. Nephrol. Dial. Transplant. 19 (2004) 365
9. Savige J., Paspaliaris B., Silvestrini R., Davies D., Nikoloutsopoulos T., Sturgess A., Neil J., Pollock W., Dunster K., and Hendle M. A review of immunofluorescent patterns associated with antineutrophil cytoplasmic antibodies (ANCA) and their differentiation from other antibodies. J. Clin. Pathol. 51 (1998) 568
10. Savige J., Gillis D., Benson E., Davies D., Esnault V., Falk R., Hagen E., Jayne D., Jennette J., Paspaliaris B., Pollock W., Pusey C., Savage C., Silvestrini R., van der Woude F., Wieslander J., and Wiik A. The international consensus statement on testing and reporting antineutrophil cytoplasmic antibodies (ANCA). Am. J. Clin. Pathol. 111 (1999) 507
11. Saxon A., Shanahan F., Landers C., Ganz T., and Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J. Allergy Clin. Immunol. 86 (1990) 202
12. Tan E., Cohen A., Fries J., Masl A., McShanes D., Rothfield N., Schaller J., Talal N., and Winchester R. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25 (1982) 1271
13. Tozzoli R., Villalta D., Kodermaz G., Bagnasco M., Tonutti E., and Bizzaro N. Autoantibody profiling of patients with autoimmune thyroid disease using a new multiplexed immunoassay method. Clin. Chem. Lab. Med. 44 (2006) 837
14. Trevisin M., Pollock W., Dimech W., Melny J., Paspaliari B., Gillis D., Wong R., and Savige J. Antigen-specific ELISAs have different sensitivities for active and treated vasculitis, and for non-vasculitic disease. Am. J. Clin. Pathol. 129 (2008) 42
15. Vercammen M., Meirlaen P., Sennesael J., Velkeniers B., T'Kint S., Verbruggen L., Haemtjens P., Broodtaerts L., Demanet C., and De Waele M. Diagnostic accuracy of the FIDIS multiplex fluorescent microsphere immunodetection system for antiextractable nuclear antigen (ENA) antibodies in connective tissue diseases. Clin. Chem. Lab. Med. 45 (2007) 505
16. Xiao H., Heeringa P., Hu P., Liu Z., Zhao M., Aratani Y., Maeda N., Falk R., and Jennette J. Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J. Clin. Invest. 110 (2002) 955
17. Yang Y., Hutchison M., Littlejohn G., and Boyce N. Flow cytometric detection of antineutrophil cytoplasmic autoantibodies. J. Immunol. Methods 172 (1994) 77
18. Yiannaki E., Zintzaras E., Analatos A., Theodoridou C., Dalekos G., and Germenis A. Evaluation of a microsphere-based flow cytometric assay for diagnosis of celiac disease. J. Immunoass. Immunochem. 25 (2004) 345