Effects of voluntary exercise on heart function in streptozotocin (STZ) - Induced diabetic rat

International Journal of Diabetes and Metabolism

Volumn 15, Issue 2, 2007, Pages 32-37

  Howarth, Frank Christopher ^a   Al Ali, S ^a   Al Sheryani, S ^a   Al Dhaheri, H ^a   Al Junaibi, S S ^a   Almugaddum, F A ^a   Qureshi, M A ^a   Ljubisavijevic, M ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Diabetes mellitus; Heart muscle; Streptozotocin; Ventricular myocytes; Voluntary exercise

Indexed keywords

CALCIUM ION; GLUCOSE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DIABETES MELLITUS; ELECTROSTIMULATION; EXERCISE INTENSITY; EXERCISE TOLERANCE; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART PERFORMANCE; HEART VENTRICLE; KINESIOTHERAPY; MALE; NONHUMAN; RAT; RUNNING; STREPTOZOCIN DIABETES; VOLUNTARY MOVEMENT; WEIGHT CHANGE;

EID: 46149122301     PISSN: 16067754     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Loganathan R, Bilgen M, Al Hafez B, et al. Exercise training improves cardiac performance in diabetes: in vivo demonstration with quantitative cine-MRI analyses. J Appl Physiol 2007; 102: 665-672.
2. Chipkin SR, Klugh SA, Chasan-Taber L. Exercise and diabetes. Cardiol Clin 2001; 19: 489-505.
3. De Angelis KL, Oliveira AR, Dall'Ago P, et al. Effects of exercise training on autonomic and myocardial dysfunction in streptozotocin-diabetic rats. Braz J Med Biol Res 2000; 33: 635-641.
4. Woodiwiss AJ, Kalk WJ, Norton GR. Habitual exercise attenuates myocardial stiffness in diabetes mellitus in rats. Am J Physiol 1996; 271: H2126-H2133.
5. Howarth FC, Qureshi MA. Effects of carbenoxolone on heart rhythm, contractility and intracellular calcium in streptozotocin-induced diabetic rat. Mol Cell Biochem 2006, 289: 21-29.
6. Howarth FC, Qureshi MA, White E. Effects of hyperosmotic shrinking on ventricular myocyte shortening and intracellular Ca (2+) in streptozotocin-induced diabetic rats. Pflügers Arch 2002; 444: 446-451.
7. Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001; 50: 537-546.
8. Vanderweele DA. Insulin and satiety from feeding in pancreatic-normal and diabetic rats. Physiol Behav 1993; 54: 477-485.
9. Chakraphan D, Sridulyakul P, Thipakorn B, et al. Attenuation of endothelial dysfunction by exercise training in STZ-induced diabetic rats. Clin Hemorheol Microcirc 2005; 32: 217-226.
10. Broderick TL, Poirier P, Gillis M. Exercise training restores abnormal myocardial glucose utilization and cardiac function in diabetes. Diabetes Metab Res Rev 2005; 21: 44-50.
11. Choi KM, Zhong Y, Hoit BD, et al. Defective intracellular Ca(2+) signaling contributes to cardiomyopathy in Type 1 diabetic rats. Am J Physiol 2002; 283: H1398-H1408.
12. Bracken N, Howarth FC, Singh J. Effects of Streptozotocin-Induced diabetes on contraction and calcium transport in rat ventricular cardiomyocytes. Ann N Y Acad Sci 2006; 1084: 208-222.