The effect of nitroaromatics' composition on their toxicity in vivo: Novel, efficient non-additive 1D QSAR analysis

Chemosphere

Volumn 72, Issue 9, 2008, Pages 1373-1380

  Kuz'min, V E ^a,b   Muratov, E N ^a,b   Artemenko, A G ^b   Gorb, L ^a,c   Qasim, M ^c   Leszczynski, J ^a,c  

^a JACKSON STATE UNIVERSITY   (United States)

^b A V BOGATSKY PHYSICO CHEMICAL INSTITUTE   (Ukraine)

^c US ARMY ENGINEER RESEARCH AND DEVELOPMENT CENTER   (United States)

Author keywords

Nitroaromatic compounds; QSAR; SiRMS; Toxicity in vivo

Indexed keywords

AROMATIC COMPOUNDS; COMPOSITION EFFECTS; FOOD ADDITIVES; PHOTOACOUSTIC EFFECT; SILANES; TELLURIUM COMPOUNDS; TOXICITY;

CONCENTRATION (COMPOSITION); IN-VIVO; LETHAL DOSE (LD); MOLECULAR FRAGMENTS; NITRO-AROMATICS; NITROAROMATIC COMPOUNDS; NON-ADDITIVE; QSAR ANALYSIS;

MICROFLUIDICS;

ALANINE; AROMATIC NITRO COMPOUND; BENZENE;

AROMATIC HYDROCARBON; BIOCHEMICAL COMPOSITION; DOSE-RESPONSE RELATIONSHIP; ESTIMATION METHOD; EXPLOSIVE; PERFORMANCE ASSESSMENT; TOXICITY TEST; VIRTUAL REALITY;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL COMPOSITION; DRUG EFFECT; IN VIVO STUDY; LD 50; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; TOXICITY;

HYDROCARBONS, AROMATIC; MODELS, MOLECULAR; NITRO COMPOUNDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

RATTUS;

EID: 46149119619     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.04.045     Document Type: Article

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